فهرست مطالب منوچهر سلطانی

This study aimed to assess the efficacy and safety of the oral use of ibuprofen suspension in various doses in the treatment of PDA (Patent ductus arteriosus) in mature babies. Mature babies (37-42 weeks) aged more than 3 days who had been diagnosed with PDA were involved in this study. For the measurement of the ratio of left atrial to aortic root diameters (La/Ao) Color, pressure gradient and the internal ductal diameter, Doppler echocardiography (ECHO) was performed. This clinical trial was performed on 60 infants born born between August 2013 to August 2015.

This clinical trial study was performed on 60 infants were randomly born between August 2013 to August 2015 which Randomly divided into two groups: The first group, received oral ibuprofen in three doses (5, 5, 10 mg/kg at 24-hour intervals) and the second group received an early dose of OIS, in two doses of 10 mg/kg after 24 and 48 hours (totally 20 mg/kg). A follow-up ECHO was performed 48 hours and 2 weeks after treatment by the same pediatric cardiologist who was not aware of the study groups. Evaluation of changes in platelet count, blood urea nitrogen, creatinine and complications of thrombocytopenia, evaluation of elevated serum creatinine, and complications of gastrointestinal bleeding were compared between the two groups using statistical analysis.

Seventy-three percent (73%) patients in the first group and seventy-six (76%) patients in the second group had successful PDA closure in the first 48 hrs. No statistically significant difference between the two groups (P=0.0001) was obtained and the highest response time was observed in the first 48 hours of treatment. After 2 weeks, the PDA closure in both groups was completely successful (100%). No specific side effects were observed between the two groups.

We conclude that higher doses of ibuprofen (20 and 2×510 mg/kg) do not show better results for PDA closure without renal or gastrointestinal complications.

Metabolic syndrome encompasses a series of metabolic disorders associated with increased cardiovascular risk. Currently, some studies are performed on the effects of physical activity as an alternative treatment for metabolic syndrome. To this end, the present study was set to assess the probable effects of continuous and interval aerobic trainings on metabolic syndrome among the elderly men.
60 eligible elderly men were selected and assigned to three groups of: continuous training, interval training and the control. The initial blood samples were taken to record cardiovascular risk factors. After 48 hours, the subjects in the experimental group performed pre-designed training for 6 weeks and 3 sessions per week and the control group continued their daily activities. At the end of the training, further blood samples were taken again. The data were analyzed using one-way ANOVA, Scheffe post hoc and dependent t-test.
Findings of this study revealed that after six weeks of continuous aerobic exercise training, systolic blood pressure, blood sugar and triglycerides significantly decreased. However, waist circumference and HDL did not show any significant change. The findings of this study showed significant changes in blood sugar, triglycerides and HDL in the interval training group. However, blood pressure and waist circumference did not indicate any significant changes.
According to the findings of this research, it can be asserted that both methods of aerobic training positively affect blood glucose and triglyceride signifying that interval aerobic exercise plays a major role in increasing HDL, while continuous aerobic exercise reduces systolic blood pressure.

For the effective performance of engineering jobs general aptitude has the principal role. However, in selecting engineers in Iran, only scientific tests and personality–based interviews have been used. In the current study, the relation between engineers general aptitude and their job performance in saipa car company (N=106) has been investigated. Engineer's general aptitude is measured by General Aptitude Tests Battery (GATB) which was the main official selection instrument in the five last decades. Psychometric characteristics of these tests (reliability and validity) were established on industrial companies engineers in Isfahan, then engineers job analysis was performed via Position Analysis Questionnaires (formerly performed in Iran Gas Company by Oreizy 1383, Nouri & oreizy, 1385), and the relation between job dimension and aptitudes was determined. At last, Suggestions were made for GATB in Iran industry.