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Due to the resistance of microorganisms against antibiotics, the use of medicinal herbs as alternative medicines has become commonplace. The purpose of this study was to explore the antimicrobial effects of aqueous, ethanolic and acetonic extracts of Rosa damascenon on E. coli as one of the most common pathogenic bacteria.

Extraction was carried out using soaking method. To determine the antimicrobial effect of different extracts of Rosa damascenon, Agar diffusion and minimum inhibitory concentration (MIC) methods were employed.

The results showed that ethanolic extract has better antimicrobial effect than other extracts. The halo size and the minimum inhibitory concentration for the ethanolic extract of Rosa damascenon were 21mm and M=25μg / ml respectively. The aqueous extract of Rosa damascenon was free of any antimicrobial effect against E.coli.

Because of the antimicrobial activity of ethanolic extract of Rosa damascenon, clinical studies can be conducted to illuminate the effectiveness of ethanolic extract of Rosa damascenon in treating infections.

Herbal essences and extracts have vast applications in medical field and food industry. They also have antimicrobial effect on broad spectrum of microorganisms. In this research the effect of ethanol extracts of damask rose and Aloevera on E.coli bacteria has been studied. Distillation was done with soaking method; after providing mentioned extracts, Agar diffusion was used to determine antimicrobial effect of Ethanol extracts of damask rose and Aloevera on E.coli bacteria. Minimum restraining concentration (MIC) was measured by subtilty pipe method. Results showed ethanol extracts of damask rose has more antibacterial effect on E.coli bacteria in comparison with ethanol extracts of Aloevera.Corona diameter and minimum restraining concentration for ethanol extract of damask rose are 14 mm and MIC=25 Mg/ml respectively. Corona diameter and minimum restraining concentration for ethanol extract of Aloevera are 7mm and MIC = 50Mg/ml respectively. Extract of damask rose has more antibacterial effects in comparison with extracts of Aloevera. Also, admixtion of ethanol extracts of damask rose and Aloevera leads to decrease of antibacterial effect of this extract.