فهرست مطالب هاجر خضرایی

obesity has become a serious concern for public health, which will lead to many risk factors; The main purpose of this research was to determine the effectiveness of life skills on tolerance of failure, marital heartbreak and irritability in obese people.Research

The design of this semi-experimental research was of pre-test-post-test type. The statistical population of this research included all obese people referred to obesity clinic of Ghadir Mother and Child Hospital, simple random sampling method was selected and these people were randomly assigned to two control groups (30 people) and experiment (30 people) was assigned. For the experimental group, 10 sessions (60 minutes each session) of the life skills training course were conducted to collect information from Harrington's frustration tolerance questionnaires and Bass and Plomin's irritability questionnaires. The data were analyzed by multivariate covariance analysis and spss version 26 software.

The results indicated that the significance level of the statistical test of multivariate covariance analysis is smaller than the significance level (0.05); Therefore, there is a significant difference between failure tolerance and irritability of the two groups in the post-test phase, in other words, life skills training has a significant effect on improving failure tolerance and irritability in obese people.

Therefore, teaching life skills by improving and increasing failure tolerance of obese people can make them feel less frustrated and lonely. These people can have more control over their anger and stress and are able to share their needs, desires and interests with others.

Cardiac Na+ channels are responsible for the excitation of the cardiac cells. Hyperglycemia is the chief symptom of diabetes and several other complications. Although many studies have been conducted on diabetic cardiomyopathy, the role of high glucose on sodium current has not been completely clarified. In the present study, the authors investigated the role of high glucose concentration on human cardiac sodium channels current in transfected HEK293 cells.

The authors evaluatedglucose effects on sodium current using the whole-cell patch-clamp technique.

The data indicated that Na+ current was significantly modified with an overnight exposure to high glucose. For steady-state activation, high glucose-induced insignificant hyperpolarizing shifted the V1/2. Steady-state inactivation shifted to more negative potentials with glucose exposure (p < 0.001).

Data suggested that the glucose effect on two forms of sodium channel gates (activation and inactivation) raises the possibility of metabolic modulations of sodium channel activity. A hyperpolarized shift of activation and inactivation is supposed to enhance cardiac cell excitability.

Colorectal cancer is a chronic disease that reduces the patients’ quality of life. Hence, it is essential to have self-care ability. This study aimed to investigate the effect of the family-centered empowerment model on the self-care ability of patients with colorectal cancer.

The present study is a randomized controlled study. The statistical population consisted of all patients referring to the surgery ward of the colorectal clinic affiliated with Shahid Faghihi Hospital in Shiraz in 2018. A total of 72 patients were selected by convenience sampling method and randomly allocated into control and experimental groups. A researcher-made questionnaire was used to collect data. The duration of this study was 9 months.

The results show that the mean score of total self-care ability and its components in the experimental group after the intervention had a significant increase compared to baseline (p<0.001) and the mean score of total self-care ability and its components in patients in the control group after the intervention was significantly higher than before the intervention (p<0.05). Moreover, the score of total self-care ability and its components in patients in the experimental group increased significantly more than the control (p<0.001) .Lastly, the mean score of total self-care ability and its components (except for the visit component) after intervention in the experimental group was significantly higher than the control (p<0.05).

The family-centered empowerment model can affect the self-care ability of patients with colorectal cancer. It is suggested that non-pharmacological interventions be combined with medical interventions in treatment plans.

Sacrococcygeal Pilonidal disease is a relatively common disease with high morbidity. This medical condition has been more detected in young adult men. Different types of management have been applied depending on the extension and severity of the disease, including resection without repair, primary closure, and using different methods of flap reconstruction.

In this cross-sectional study, 405 patients with the pilonidal disease were evaluated. Patients treated with different surgical techniques between 2006 to 2011 in Shahid Faghihi Hospital and Namazee Hospital of Shiraz University of Medical Sciences. Demographic data were registered and the surgical methods and complications were identified.

Most of the patients were young men (265 cases, 65.4%) and their main complaints were discharge and pain (353 cases, 87.2%) in the Sacrococcygeal area. Comparison of the surgical methods including resection with an open wound, primary closure, and Rhomboid flap indicates that recurrence was seen low in all three techniques (33 cases, 8.2%), especially in the surgery using Rhomboid flap. High-protein and high-caffeine meal (291 cases, 71.8%) and living in the warm and humid climates (348 cases, 85.9%) have been evaluated as predisposing factors for disease development.

Due to primary results, the rhomboid/Limberg flap procedure should be considered as the preferable surgery method for the treatment of Sacrococcygeal Pilonidal disease. Further investigations are inevitable to find the role of factors like high-protein and high-caffeine meals on the incidence of pilonidal disease.