مقالات رزومه عظیمه قادری
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Trend of Congenital Hypothyroidism Incidence and Its Affecting Factors in Shahr-e-Kord, Western IranBackground
Congenital hypothyroidism is one of the most common endocrine disrupters and metabolism, and is one of the most important preventable causes of physical and mental disabilities.
ResultsOverall, 111 cases were diagnosed with hypothyroidism, which made the prevalence value equal to 2 cases per 1000 births. The prevalence in females and males was 1.9 and 2.2 per 1,000 birth, respectively. The odds ratio for this disorder was 4.47(2.42-9.28) for the neonates with a family history of hypothyroidism and 1.72(1.05-2.82) for those born through cesarean.
ConclusionThe incidence of this disorder is similar in males and females, and the incidence of this disease in people with a family history is far more than others.
Keywords: Congenital hypothyroidism, Incidence, Trend, Risk factors, Predictors} -
BackgroundRoad traffic accident is one of the most important causes of disability and death in the young population. A significant number of people injured in road traffic accidents die after they arrive at the hospital.ObjectivesThis study aimed to assess the trend of mortality in road traffic accidents and forecast it for the coming years using time series modeling.MethodsThis study investigated the trend of road traffic accidents and their victims in Najafabad, Iran, between 2011 and 2017. The ARIMA time series model was fitted on the obtained data and the best model was selected based on the least mean square error. Moreover, the model’s goodness of fit was investigated by residuals ACF and PACF plots as well as Ljung-Box chi-square statistics.ResultsThe trend analysis and ARIMA models were investigated, and the results showed a descending trend of fatalities due to traffic accident during 2011-2017. Afterwards, some models were fitted and ARIMA was selected (0, 1, 1), because it had the lowest mean square error value. By fitting the best model, the trend of traffic accident mortality was forecasted for five years (2018 to 2022). Finally, the forecasted values showed that future traffic accident mortalities had a decreasing trend.ConclusionThe trend of mortality due to road traffic injuries declined, indicating a decreasing trend in deaths for the upcoming years. Therefore, the interventions that have been applied in recent years may be considered as useful.Keywords: Road accident, time series, Trend, seasonality}
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سابقه و هدفبیماری مادرزادی هیپوتیروئیدی تنها در صورت تشخیص و درمان به موقع قابل پیشگیری است. مطالعه حاضر جهت بررسی نتایج غربالگری این بیماری از شروع برنامه (1385) تا سال 1393 انجام شده است.مواد و روش هااین مطالعه به صورت مقطعی انجام شد. تعداد 54468 نوزاد طی سال های 1385 تا 1393 تحت آزمون غربالگری قرار گرفتند و از این تعداد 111 نوزاد به عنوان بیمار شناسایی شدند. تحلیل داده ها با استفاده از شاخص های مرکزی و پراکندگی و آزمون دقیق فیشر انجام شد.نتایجبیشترین علت تکرار نمونه گیری مربوط به نامناسب بودن نمونه (59/2 درصد) بود. به طور کلی شیوع برابر 2 مورد در هزار مورد تولد بود و در دختر و پسر به ترتیب 1/9 و 2/2 مورد در هزار مورد تولد بود که این اختلاف از لحاظ آماری معنی دار نبود (0/346=P). میزان فراخوان به طور کلی 46/65 در هزار تولد بود. 27 درصد از بیماران سابقه ابتلا به بیماری کم کاری تیروئید در فامیل داشتند. هم چنین، 27/9 درصد والدین بیماران ازدواج فامیلی داشتند. بیشترین سهم در بروز بیماری (33/4 درصد) در تابستان اتفاق افتاده بود.نتیجه گیرینتایج نشان داد که کیفیت نمونه گیری های اولیه از پاشنه پا چندان مناسب نبوده و لازم است با آموزش افرادی که مسئولیت نمونه گیری های اولیه را بر عهده دارند باعث کاهش نمونه گیری های مجدد و در نهایت مانع از دست دادن زمان درمان شد. شیوع کلی این بیماری طی این سال ها مشابه شیوع کلی در کشور و بالاتر از استاندارد جهانی می باشد.کلید واژگان: هیپوتیروئیدی مادرزادی, غربالگری, شیوع, میزان فراخوان}Screening for congenital hypothyroidism in Shahr-e-Kord: prevalence and recall rate during 2006-2014Feyz, Volume:20 Issue: 6, 2017, PP 574 -580BackgroundAs the congenital hypothyroidism is preventable only by the timely diagnosis of the disease, the aim of present study is to evaluate the results of the screening program carried out during 2006-2014.Materials And MethodsOne hundred and eleven out of the 54,468 newborn screened for this cross sectional study during 2006 to 2014 were identified as the cases. Fisher's exact test at a significance level of 5% was used for the analysis.ResultConsidering the prevalence rate of 2 per 1000 births, the rate for girls and boys were 1.9 and 2.2 per 1000 births, respectively. The difference between the rates was not statistically significant. The recall rate was 46.65 per 1000 births. Twenty seven percent of the patients had a positive history of disease and 27.9% the familial relationship. The highest prevalence of the disease (33.4%) was in the summer.ConclusionThe findings disclosed that the inaccuracy of the initial sampling from the heel of the cases. So for the reduction of sampling errors and not wasting the golden time of treatment, it is mandatory to employ the trained personnel for initial sampling. Although above the international standard level, the overall prevalence of the disease during these years was the same rate in the country.Keywords: Congenital hypothyroidism, Screening, Prevalence, Recall rate}
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