مقالات رزومه فاطمه راسخ

The aim of this study was to The role of Anvillea garcinii extract and exercise on liver and kidney factors in hypercholesterolemia rats.

35 of male winstar rats randomly divided into five groups of seven, including healthy control group (Con), control hypercholesterolemia (Hc), Anvillea garcinii extract at a dose of 100 mg / kg, (Ext), training group (E ), Extract-exercise (E-Ext). Endurance exercise for 8 weeks, for 30 minutes and three sessions per week, it was performed at a speed equivalent to 14-17 m / min. Then by biochemical auto-analyzer and by Kit test the amount of biochemical factors of renal and hepatic functions (level of Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), BUN, Creatine, Albumin, Bilirubin and total protein were assayed. Statistical analysis used ANOVA test and Tukey test.

The results of statistical tests show that all factors (AST, ALT, BUN, Keratin, albumin, bilirubin and total protein) except ALP were significant in comparison between groups. The results of Tukey post hoc test showed that the amount of AST in the exercise-extract group was slightly higher than the control group, while ALT was significant. The results also showed that renal function (BUN, Creatine, albumin, bilirubin and total protein) in the exercise-extract group was significantly increased compared to the control of hypercholesterolemia.

Although the consumption of Anvillea garcinii extract along with exercise is effective on some factors, but its use should be controlled.

Due to the similarity of many medicinal plants and the perfumers ignorance about the science of botany, many unintended frauds are occurring in the supply of medicinal plants, like the presentation of different types of medicinal plants called lemon balm. This study was aimed at identifying the species offered under the name of lemon balm as well as comparing the antioxidant activity and phenolics content of these species. In this study, the species that are offered as lemon balm in the perfumeries of Yazd and Shiraz cities were collected and then scientifically identified using the valid botanical keys. In this study, the anti-radical activity was evaluated by the DPPH test. In addition, the total phenols content was measured by the Folin Ciocalteu method. Based on the results of species identification, it was proved that three species of Asperugo procumbens L., Hymenocrater elegans Bunge, and Melissa officinalis L. are sold in Yazd city under the name of lemon balm and H. elegans had the highest percentage of supply. Two species, M. officinalis and Stachys inflata Benth., also are sold under the name of lemon balm in Shiraz city, where the largest supply belonged to S. inflata. Also, M. officinalis and A. procumbens had respectively the highest and lowest amounts for the traits including total phenols and antioxidant activity.

The aim of this study was to evaluate the effect of exercise and Anvillea garcinii extract on sex hormones in male rats with hyperlipidemia.

35 male wistar rats randomly divided into five groups (n=7 for each group), including: 1) control group (Con), 2) hypercholesterolemia (Hc), 3) Anvillea garcinii extract (Ext; 100 mg / kg), 4) training group (E), 5) Extract-exercise (E-Ext). Exercise was performed for eight weeks, 30 minutes and three sessions per week equivalent to a speed of 14-17 m / min.  Levels of testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and prolactin were measured by radioimmunoassay and hormone kits. ANOVA test was used to determine the differences between groups.

The results showed a significant difference between the levels of FSH, LH, Prolactin and Testosterone between the groups. The results of Tukey post hoc test showed that FSH, LH and Testosterone levels between E-Ext and Hc groups (p = 0.000) (p = 0.001) (p = 0.001), Ext (p = 0.000) (P = 0.000) (p = 0.008) and E (p = 0.000) (p = 0.011) (p = 0.015) and Prolactin level between E-Ext groups with Hc (0.015). There was a significant difference between Ext (p = 0.046) and E (p = 0.012). The results showed all sexual hormones except Prolactin increased in the E-Ext group compared to the Hc group.

Consumption of plant extracts along with exercise can have positive effects on sex hormones.

The present study aimed to compare the effects of three therapeutic methods (including herbal, atorvastatin, and exercise) on liver enzymes and lipid profiles in hypercholesterolemic rats.

A number of 32 male Wistar rats were randomly assigned to four groups (n=8), including hypercholesterolemia (Hc) control group, anvil extract at a dose of 100 mg/kg, (Ext), exercise (E), and atorvastatin (AT) at a dose 10 mg/kg. Endurance training, anvil extract, and atorvastatin were performed three sessions per week for 8 weeks. Thereafter, liver biochemical tests, including alkaline phosphatase (ALT), aspartate aminotransferase (AST), and lipid profiles were performed using a biochemical autoanalyzer (Ra-2000 made in USA) and the kits provided by Pars Azmun company. The data were analyzed in SPSS software using analysis of variance (ANOVA) and Tukeychr('39')s test were used for data analysis.

The results of statistical analysis indicated that all variables (e.g., Alanine transaminase, Triglyceride, High-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL), except for ALT, AST, and cholesterol, were significant in all groups. The results of the statistical analysis demonstrated that triglycerides and VLDL significantly reduced in the atorvastatin and exercise groups, compared to the hypercholesterolemic control group. Furthermore, HDL had a significant increase in the exercise group, compared to the atorvastatin, extract, and control groups. In addition, LDL significantly decreased in the exercise group, compared to the atorvastatin group.

The results of the current study pointed to the similar effects of medication and exercise on the improvement of some lipid profiles. Nonetheless, exercise is advantageous over the use of medicine and herbal extracts due to the positive effects of exercise on the reduction of blood lipids and the absence of any side effects.

 Inhalation of dust particles is prone to chronic diseases, and regular exercise reduces the risk of cardiovascular disease and improves blood variables. The purpose of this study was to investigate the role of physical activity on blood factors, lipid profile, and liver enzymes in tile factory workers.

This is a cross-sectional study. 70 workers who were eligible to participate in the study were selected based on the sampling method available at the workplace. According to the Beck questionnaire, 15 people were included in each active and inactive groups. After 12 hours of workerchr('39')s last meal, 10 ml of venous blood was used to evaluate biochemical variables of Blood factors (RBC, Hematocrit, Hemoglobin, WBC), lipid profile (Cholesterol, Triglyceride). Liver enzyme (ALT, AST, ALP) tests of both groups were performed in the occupational medicine laboratory of Meybod city, and SPSS Ver.23 software was used for analysis.

 The results showed that red blood cells (p = 0.003) and hemoglobin (p = 0.034) in the active group were significantly higher than the inactive group. Also triglyceride (p = 0.025) and cholesterol (p = 0.042) of liver enzymes, (p = 0.011) ALT and AST (p = 0.047) were significantly lower.

 It seems that physical activity can have a positive effect; it can improve blood factors, liver enzymes, and fat profile in workers. According to the results, tile factory workers can achieve the desired blood factors with minimal physical activity.

The Matricaria chamomile are medicinal and aromatic plants belonging to the Asteraceae family, which have many pharmaceutical properties. Salicylic acid naturally occurs in plants at a very low concentration. It is a common plant-produced signal molecule that is responsible for inducing tolerance to a number of mutation. The present study was performed to evaluate the effect of various concentrations of salicylic acid on biochemical and physiological characteristics of M. chammomile. The seeds of M. chammomile were grown in the greenhouse with the mean day/night temperature and relative humidity of 29 ± 4˚C, 38 ± 5% RH/17 ± 2˚C, 59 ± 5% RH respectively. To investigate the effects of salicylic acid on morphological characteristics of M. chammomile .Fourteen weeks old plants were subjected to different levels of salicylic acid [control, 150, 300, and 450 mg l-1]. Our results showed that salicylic acid caused a significant change in proline content, photosynthetic pigments and antioxidant activity in M. chammomile but phenolic compounds has shown different profiles. The essential oil components of M. chammomilewere identified and analyzed by GC/MS and GC technique. Polyphenol components were identified and analyzed by HPLC method. The main components of essential oil were α-Bisabolol oxide A, Chamazulene and En-in-dicycloether. The main components of polyphenols wereChloregeni acid, Caffeic acid, Catechin, Sinapic acid, Hesperidin, Ellagic acid, Quercetin, Eugenol. The proportions of these main compounds and synthesis of some important essential oil components were induced by salicylic acid.