مقالات رزومه محمد ماذنی

Ficus carica (fig) and Olea europaea (olive) are valuable nutritional plants that are widely used in diet and traditional medicine. Different parts of the plants such as fruit and leaves contain beneficial compounds with diverse pharmacological properties, among which anti-inflammatory activities are remarkable. The purpose of this review is to discuss the anti-inflammatory effects of F. carica and O. europaea with emphasis on their impact on pivotal pro-inflammatory cytokines including IL-1, IL-6, and TNF-α. 

To prepare the present review, the sites utilized included Scopus, PubMed, Science Direct, and Google Scholar and studied relevant articles from 2000 until 2021. 

As a result, we observed that most of the compounds in fig and olive including polyphenols, flavonoids, etc., exert their anti-inflammatory effects through inhibiting or decreasing pro-inflammatory cytokines. Moreover, some natural antioxidants are common between these two plants. 

We suggest that consuming figs and olives simultaneously or alone can be useful in the prevention or treatment of inflammatory diseases.

Liver is the most important organ of drugs and xenobiotics metabolism and any damage to the liver is associated with dysfunction of this organ. This study was carried out to find the possible additive effect of the co-administration of Cinnamomum zeylanicum (cinnamon) and Zingiber officinale (ginger) extracts on carbon tetrachloride (CCl4)-induced liver damage in rats.
Forty-two male Wistar rats were randomly divided into 7 groups (n=6). Group I: Normal control, Group II: Control of the extract (25 mg/kg of cinnamon extract and 125 mg/kg of ginger extract), Group III: CCl4 control, Group IV: 50 mg/kg of cinnamon extract; Group 5: 250 mg/kg of ginger extract; Group VI: As in group II, a combination of 25 mg/kg cinnamon extract and 125 mg/kg ginger extract, and group VII: 100 mg/kg of silymarin (as the standard drug). These treatments were performed daily for 14 days. On the fourteenth day, all groups received 1ml of CCl4 along with olive oil (1:1 v/v), except for the groups I and II. The last two groups received only olive oil.
Intraperitoneal injection of CCl4 into rats significantly increased the levels of liver enzymes, bilirubin, and malondialdehyde (MDA), and decreased total antioxidant and total protein levels compared to the control group (P<0.001). Pre-treatment with a combination of cinnamon and ginger extracts significantly improved these factors.
The results of this study showed that co-administration of cinnamon and ginger extracts is more efficient in protecting liver from the damaging effects caused by CCl4.