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فهرست مطالب abdolhassan kazemi

  • سمیه رزم آرای*، پویا حسین زاده، عبدالحسن کاظمی، شیوا حیدری، فاطمه حسن زاده، ثنا کاظمی
    زمینه و هدف
    هوش هیجانی یکی از مهم ترین عواملی است که بر آموزش، عملکرد و کیفیت تعاملات بین افراد مختلف در یک جامعه تاثیر می گذارد. امروزه توجه به ابعاد مختلف هوش هیجانی و مدیریت صحیح آنها موضوع مهمی در مقوله مدیریت آموزشی می باشد. هدف از انجام این مطالعه، تعیین ارتباط هوش هیجانی و رفتارهای پرخطر در دانشجویان رشته های علوم پزشکی دانشگاه آزاد اسلامی واحد ارومیه بود.
    مواد و روش ها
    این پژوهش یک مطالعه توصیفی- مقطعی می باشد و ارتباط بین هوش هیجانی و رفتارهای پرخطر را در میان دانشجویان رشته های علوم پزشکی دانشگاه آزاد اسلامی واحد ارومیه در سال 99- 98 بررسی کرده است. جامعه آماری این مطالعه شامل 260 نفر از دانشجویان رشته های علوم پزشکی دانشگاه آزاد ارومیه است که با استفاده از پرسش نامه هوش هیجانی گلمن مورد ارزیابی قرار گرفتند.
    یافته ها
    این مطالعه نشان داد که دانشجویان برای کنترل و ارتقای هوش هیجانی، نیاز به مداخله دارند تا تاثیر هوش هیجانی افراد موردمطالعه در بروز رفتار پرخطر کاهش یابد (0/001=p). همچنین بروز رفتار پرخطر در دانشجویان دختر به طور معناداری بیشتر از دانشجویان پسر بود (0/001=p).
    نتیجه گیری
    نتایج پژوهش حاضر نشان داد که ارتباط نزدیکی بین هوش هیجانی و بروز رفتار پرخطر در دانشجویان وجود دارد و به منظور کنترل هوش هیجانی و ارتقای ابعاد مختلف آن نیازمند مداخلات مثبت در قالب کارگاه های آموزشی و کلاس های فوق برنامه ای برای دانشجویان، استادان و والدین دانشجویان می باشد.
    کلید واژگان: هوش هیجانی, رفتارهای پرخطر, دانشجویان علوم پزشکی}
    Somayeh Razmaraei *, Pouya Hosseinzadeh, Abdolhassan Kazemi, Shiva Heidari, Fatemeh Hassanzadeh, Sana Kazemi
    Introduction
    Emotional intelligence (EI) is one of the most important factors that affect the education, performance and quality of interactions between different people in a society. Today, paying attention to different dimensions of EI and their proper management is an important issue in the rationale of educational management. The aim of this study was to determine the relationship between EI and HRB in medical students of Islamic Azad University, Urmia Branch.
    Materials and Methods
    This is a cross-sectional descriptive study that investigated the relationship between EI and HRB among medical students of Islamic Azad University, Urmia Branch in 1998-99. The statistical population of this study included 260 medical students of Urmia Azad University who were evaluated using the Gelman EI Questionnaire.
    Results
    This study showed that students need intervention to control and promote EI to reduce the impact of EI on HRB (P=0.001). Also, the incidence of high-risk behavior in female students was significantly higher than male student (P=0.001).
    Conclusion
    The results of the present study showed that there is a close relationship between EI and the occurrence of risky behavior in students and in order to control EI and improve its various dimensions need positive interventions in the form of workshops and extracurricular classes for students, Professors and parents of students.
    Keywords: Emotional intelligence:High, Risk Behaviors:Medical students}
  • Mohammad Abbasi, Narges Eskandari, Akram, Heidari, Morteza Heidari, Sadegh Yoosefee, Seyed-Hasan Adeli, Abdolhassan Kazemi
    Background

    An overview of spiritual care studies can help reveal the dimensions of spiritual care and summarize the findings of available studies. Thus, we designed the present study based on existing studies to explain the dimensions of spiritual care.

    Materials and Methods

    In this thematic analysis, we gathered the related articles published in Persian and English in the last 8 years (2013– 2021) with the help of the keywords of Care, Support, Spirituality, Religion, Treatment, Hospice, and Palliative, and searching in electronic databases, including PubMed, Scopus, Web Of Sciences, Magiran, Islamic Science Citation (ISC), and Scientific Information Database (SID). We accurately studied 79 articles that met the inclusion criteria, and then the spiritual care components were extracted and coded, and finally, the codes were categorized as themes and sub‑theme.

    Results

    Thematic analysis of available studies revealed that the dimensions (theme) of spiritual care include: spiritual and religious assessment, developing a structure for providing spiritual care, establishing effective and supportive communication with the patient, training the patient, answering his questions, encouraging, maintaining, and improving social communications, encouraging the patient to live happily, helping the patient to achieve peace and calmness, supporting for spiritual rituals and activities, supporting and training the patient’s family, and supporting the dying patient.

    Conclusions

    Spiritual care includes various and numerous dimensions. Considering the widespread dimensions of spiritual care, it seems necessary to design and plan appropriate studies to reveal other spiritual care dimensions from the perspective of patients and care providers in different cultures.

    Keywords: Hospice care, palliative care, patients, spirituality}
  • Sara Ghahremanzadeh Anigh, Abdolhassan Kazemi, Saeed Khamnei, Mehran Seif-Farshad, Firooz Hasanzadeh, Farzad Rahmani*
    Background

    Moral intelligence is one of the several types of human intelligence. It is the ability to understand right from wrong and behave based on the value which is believed to be right.

    Objectives

    This study was conducted to evaluate the effect of a professional ethics workshop on the moral intelligence of prehospital emergency technicians in East Azerbaijan Province, Iran, and consequently the improvement of their performance and increase in their work efficiency.

    Methods

    In this before- and after-interventional study conducted in Tabriz University Prehospital Emergency Center, Iran, in 2020, a total of 234 participants were evaluated. The sample was collected using the Lennick and Kiel’s Moral Intelligence Questionnaire and full census method. Before the workshop, the questionnaire was completed by the participants. After the workshop, the same questionnaire was completed again.

    Results

    The pretest and posttest scores for moral intelligence were 83.02 ± 7.33 and 83.49 ± 8.40, respectively, which showed a statistically significant difference (P < 0.05). In the three components of moral intelligence, namely consistent behaviors based on principles, values, and beliefs, persistence for the right, and responsibility for personal decisions, there were statistically significant differences (P < 0.05) before and after the workshop.

    Conclusions

    According to the results, holding a professional ethics workshop was effective in increasing the overall level of moral intelligence, particularly in the three aforementioned components of moral intelligence. It is recommended to continue holding such workshops and improve the conditions and methods of training to increase their efficiency as much as possible.

    Keywords: Moral Intelligence, Professional Ethics, Emergency Technician, Academic Performance}
  • Zahra Salehi, Azam Fattahi *, Ensieh Lotfali, Abdolhassan Kazemi, Ali Shakeri Zadeh, Saman AhmadNasrollahi
    Purpose

    The present study was performed to examine whether caspofungin-coated gold nanoparticles (CAS-AuNPs) may offer the right platform for sensitivity induction in resistant isolates.

    Methods

    A total of 58 archived Candida species were enrolled in the research. The identification of Candida spp. was performed using polymerase chain reaction-restriction fragment length polymorphism and HWP1 gene amplification approaches. The conjugated CAS-AuNPs were synthesized and then characterized using transmission electron microscopy (TEM) and Zetasizer system to determine their morphology, size, and charge. Furthermore, the efficacy was assessed based on the Clinical and Laboratory Standards Institute M60. Finally, the interaction of CASAuNPs with Candida element was evaluated via scanning electron microscopy (SEM).

    Results

    According to the TEM results, the synthesized CAS-AuNPs had a spherical shape with an average size of 20 nm. The Zeta potential of CAS-AuNPs was -38.2 mV. Statistical analyses showed that CAS-AuNPs could significantly reduce the minimum inhibitory concentration against C. albicans (P=0.0005) and non-albicans Candida (NAC) species (P<0.0001). All isolates had a MIC value of ≥ 4 µg/ml for CAS, except for C. glabrata. The results of SEM analysis confirmed the effects of AuNPs on the cell wall structure of C. globrata with the formation of pores.

    Conclusion

    According to findings, CAS-AuNPs conjugates had significant antifungal effects against Candida spp. Therefore, it can be concluded that the encapsulation of antifungal drugs in combination with NPs not only diminishes side effects but also enhances the effectiveness of the medications.

    Keywords: Candida albicans, Non-albicans Candida, CAS-AuNPs conjugate, Caspofungin}
  • Zahra Taghinejad, Mohammad Asgharzadeh, Vahid Asgharzadeh, Abdolhassan Kazemi *

    Opportunistic infections, such as mucormycosis, in coronavirus disease 2019 (COVID-19) patients has become a new health challenge. Since opportunistic infections can exacerbate COVID-19 patients' status, it is vital to identify the risk factors to prevent, diagnose, and treat them as soon as possible. Viral, fungal, environmental, and host factors may be responsible for this situation. Long hospital stays, impaired host immune system function due to viral infection, and excessive consumption of glucocorticoids in managing COVID-19 patients are the main risk factors for the increased risk of mucormycosis in COVID-19 patients. Educating health care workers and considering the association between mucormycosis of the paranasal sinuses and different strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the cause of COVID-19 can help prevent invasive fungal sinusitis in COVID-19 patients.

    Keywords: COVID-19, Risk Factor, Mucormycosis}
  • سعید دستگیری *، عبدالحسن کاظمی، محمد حیدرزاده، مرتضی علیان، بهرام صمدی، علی سیف فرشاد، فروغ السادات سیاح ملی، حسین میرزاجان زاده، مریم بیگم یاسینی
    زمینه و اهداف

    هدف مطالعه ی حاضر آن است که مصداق های «قاعده ی عسر و حرج» در وقوع ناهنجاری های مادرزادی و اختلالات ژنتیکی را توضیح و نشان دهد که براساس قوانین جاری کشور می توان از تعداد بیشتری از این بیماری ها پیشگیری نمود.

    مواد و روش ها

    در مطالعه ی حاضر داده های مربوط به بیماری های مادرزادی از 2 برنامه ی بزرگ میدانی و بر پایه ی بیش از 6465849 تولد در کشور به دست آمده است. جهت بررسی جوانب فقهی قاعده ی عسر و حرج یک بررسی جامع کتابخانه ای انجام گرفت. برای ارزیابی مصادیق قاعده ی فوق با تعدادی از علمای حوزوی بحث و تبادل نظر به عمل آمد و با متخصصین پزشکی کودکان، ژنتیک، روان پزشکی و نوزادان از لحاظ تعاریف تشخیص های مرتبط با اختلالات مادرزادی و ژنتیکی تبادل نظر و مشاوره ی گسترده ای انجام گردید.

    یافته ها

    سالانه حدود 100 هزار نفر بیمار مادرزادی و ژنتیکی به جمعیت عمومی کشور اضافه می گردد. وقوع این بیماری ها در 18 ساله ی گذشته، بیش از 3 برابر افزایش پیدا کرده است.

    نتیجه گیری

    اگر وقوع ناهنجاری های مادرزادی کنترل نشوند، به تدریج خزانه ی ژنی جمعیت را در آینده معیوب و دچار انواع نقایص ژنتیکی خواهد نمود. با استناد به قانون فعلی سقط درمانی، بیماری هایی که منجر به عسر و حرج پدر، مادر، خانواده، اجتماع و همین طور نسل-های آینده شوند را می توان به تشخیص متخصصین مربوطه در قبل از ولوج روح (تا 16 هفتگی بارداری) برای سقط درمانی ارجاع داد. با اجرای صحیح این قانون، همه ساله از ورود حداقل 70 هزار نفر با ژن های معیوب و بیماری مادرزادی و ژنتیکی به خزانه ی ژنتیکی جمعیت جلوگیری می گردد.

    کلید واژگان: ناهنجاری مادرزادی, اختلال ژنتیکی, پیشگیری, اپیدمیولوژی, نفی عسر و حرج}
    Saeed Dastgiri*, Abdolhassan Kazemi, Mohammad Heidarzadeh, Morteza Alian, Bahram Samadi, Ali Seif-Farshad, Foroogh Sadat Sayyah Melli, Hossein Mirzajanzadeh, Mariam Beigom Yasini
    Background and Objectives

    The aim of this study was to explain the examples of "the Jurisprudential Rule of "Osr o- Haraj" or Denegation of Intolerable Hardship in the occurrence of congenital anomalies and genetic disorders and show that according to the current laws of the country, more of these diseases can be prevented.

    Material and Methods

    Data for occurrence of congenital anomalies were derived from two major regional and national epidemiological studies based on 6,465,849 births in the country. A comprehensive review of literature was carried out on the details of ‘Denegation of Intolerable Hardship Rule. The details of medical termination of pregnancies diagnosed for congenital anomalies and the role of ‘Denegation of Intolerable Hardship’ principle in the prevention of birth defects were explored in several Focused Group Discussions formed by peditricians, geneticists, psychiatrists, neotatalogists and expert jurisprudents.

    Results

    The statistical estimates indicate that there are now nearly 100,000 births with one of the birth defects occurring every year in Iran. The total prevalence of the anomalies has more than tripled in the last 18 years.

    Conclusion

    The occurrence of congenital anomalies and genetic disorders will undermine the gene pool of the population if preventive measures are not properly implemented in the community genetics services to control those disorders. According to the current law on therapeutic abortion, disorders that lead to the hardships of father, mother, family, community, as well as future generations may be diagnosed by the three specialists (before the 16th week of pregnancy, the time of onsetting the soul). They can then be referred for medical abortion. A minimum of 70,000 birth defects may be avoided using the therapeutic termination of pregnancies diagnosed for congenital anomalies if the ‘no hardship and negation of distress and constriction’ principle is suitably explored in maternal, pediatric, neonatal settings and for public health authorities.

    Keywords: Congenital Anomalies}
  • Amir Mohammadzadeh, Jalil Rashedi *, Behroz Mahdavi Poor, Hossein Samadi Kafil, Mahya Pourostadi, Abdolhassan Kazemi, Mohammad Asgharzadeh
    Background

    Today, because of increasing immigration and the prevalence of drug‑resistant tuberculosis in Iran, identifying intra‑community cases is necessary in the country. It will be possible through the use of molecular epidemiologic methods. In this inquiry, in order to determine the role of immigrants in the transmission of specific strains to Iran, the studies have been examined which had been conducted based on molecular epidemiologic methods among Iranians and non‑Iranians people.

    Methods

    All studies from 1997 to the end of March 2017 were examined in three databases of PubMed, Scopus, and Google Scholar and finally, 16 studies were selected.

    Results

    The common clustering rate between Iranians and non‑Iranians was determined to be 19.8, and the intra‑community recent transmission rate was from 0% to 49% with average of 18.1%. The rate of multidrug‑resistant tuberculosis (MDR‑TB) was 12.5%, which was higher among immigrants, especially Afghans, and a significant number of the strains were Beijing.

    Conclusions

    The studies have shown that migrants, especially Afghans, are more effective in transmitting specific strains of tuberculosis to migratory areas. To control tuberculosis, it is necessary to register of immigrant’s health information, while enter to the country, so that, by doing appropriate diagnostic tests, the curing the patients, the transmission of tuberculosis to the country would be prevented.

    Keywords: Immigration, Iran, molecular typing, tuberculosis}
  • Mahya Pourostadi, Jalil Rashedi *, Behroz Mahdavi Poor, Hossein Samadi Kafil, Abdolhassan Kazemi, Ehsan Ahmadpour, Mohammad Asgharzadeh
    Background
    Tuberculosis (TB) is a public health problem in developing countries and yet the numbers of people with the disease are abundant. Early detection of transmission sources and effective treatment of the cases is essential to control the disease which will be possible by application of molecular epidemiology approaches. Studies conducted based on Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats (MIRU-VNTR) method in Muslim Middle East countries were evaluated to determine their role in TB control.
    Materials and Methods
    All studies from January 2005 to April 2016 were systematically reviewed in four electronic databases and finally 16 articles were found eligible to be included in this study. The mean clustering rate was determined as 44% and the recent transmission rate was 12.3 to 78.8% with average of 33%.
    Results
    The results showed that both reactivation and recent transmission were important in developing new cases of TB in Middle East countries; but, reactivation plays a more critical role.
    Conclusion
    Regarding to ongoing war and immigration in the region along with the increasing of drug-resistant TB, in the case of improper supervision in the future, the disease, especially drug- resistant TB, will be problematic.
    Keywords: Molecular epidemiology, MIRU-VNTR, tuberculosis, transmission, Middle East}
  • عبدالحسن کاظمی*، نصرالله مقدم شهابی، حسین ابراهیمی، حسین جباری، پویا فتحعلی زاده پراپری، علی صفایی قادری
    زمینه و هدف
    یوتانازی، به فرآیند پایان دادن به زندگی با هدف رهایی بیمار از درد و رنج اطلاق می گردد. قوانین متفاوتی برای یوتانازی در کشورهای مختلف وجود دارد و نگرش به یوتانازی در بین افراد و جوامع مختلف متفاوت است. هدف از پژوهش حاضر، ارزیابی نگرش اعضای هیات علمی دانشگاه علوم پزشکی تبریز نسبت به یوتانازی بود.
    روش بررسی
    این مطالعه یک پژوهش مقطعی و توصیفی پرسش نامه ای است که در بین سال های 1392 لغایت 1393 در دانشگاه علوم پزشکی تبریز، با جمع بندی نظرات 132 نفر از اعضا هیئت علمی دانشکده پزشکی دانشگاه علوم پزشکی تبریز انجام یافت.
    یافته ها
    بررسی پاسخ های 132 پرسش نامه نشان داد که فقط 10/2% و 6/2% پزشکان معتقدند؛ تحت شرایط خاصی به ترتیب در محیط بیمارستانی و غیر بیمارستانی (مانند منزل)، یوتانازی قابل قبول است. 59/1% و 80/6% پاسخ گویان معتقد بودند که تحت هیچ شرایطی، نباید به پزشکان اجازه یوتانازی داده شود و بقیه پاسخ گویان نظری نداشتند. متخصصین خون، انکولوژی و اعصاب و روان، بیش از سایر گروه ها (100%) مخالف با یوتانازی و پزشکان متخصص بیهوشی بیش از سایر گروه ها (50%)، در شرایط خاص موافق با انجام یوتانازی در بیماران بستری لاعلاج در بیمارستان بودند.
    نتیجه گیری
    ضمن تاکید بر تفاوت آشکار نتایج این مطالعه با مطالعات مشابه در سایر کشورها، تنها تعداد محدودی از پزشکان دانشگاه علوم پرشکی تبریز موافق با انجام یوتانازی بودند. به نظر می رسد جهت بهبود کیفیت زندگی بیمارانی که در مراحل پایانی زندگی خود قرار دارند، باید Palliative Care به صورت مناسب تری در نظام سلامت کشور رواج یابد.
    کلید واژگان: یوتانازی, نگرش, هیئت علمی, دانشگاه علوم پزشکی تبریز}
    Abdolhassan Kazemi *, Nasrollah Moghaddam Shahabi, Hossein Ebrahimi, Hossein Jabbari, Pouya Fathalizadeh Parapary, Ali Safaei Ghaderi
    Background
    Euthanasia or good death refers to the practice of intentionally ending a life in order to relieve patient’s pain and suffering. There are different euthanasia rules in each country. Attitudes toward euthanasia differ between individuals and populations, and in many studies the medical profession is more reluctant than the general public. Our goal was to explore academic staff attitude toward euthanasia in Tabriz University of Medical Sciences.
    Methods
    This is a cross sectional study that an anonymous questionnaire was sent to 132 randomly selected physicians in Tabriz Uni. of Med. Sci. between 2009-2010, consisting of 15 multiple choice questions on definition and classification of euthanasia, legal status and attitude toward euthanasia among Islamic populations. Data were analyzed with SPSS16.
    Results
    Analyzing 132 completed questions showed that only 10.2% and 6.2% endorsed the view that a physician should be permitted, under some circumstances, to allow a patient to end his or her life in hospitals and non-hospital (such as home). 59.1% and 80.6% endorsed the view that this practice should never be permitted in hospitals and non-hospital status such as her or his home. Of the groups surveyed, hematologists-oncologists and psychiatrists (100%) were most likely to oppose euthanasia and assisted suicide, and anesthesiologists (50%) were most likely to support these practices among hospitalized patients.
    Conclusion
    In sharp contrast to similar surveys conducted in other countries, only a minority of physicians supported the euthanasia in Tabriz University of Medical Sciences. It seems that palliative care needs to be stronger established and promoted within the Iranian health care system in order to improve the quality of end-of-life situations among terminally ill patients.
    Keywords: Euthanasia, Attitude, Academic staff, Tabriz University of Medical Sciences}
  • Mahya Pourostadi, Jalil Rashedi *, Behroz Mahdavi Poor, Hossein Samadi Kafil, Abdolhassan Kazemi, Mohammad Asgharzadeh
    Background
    Today because of immigration, HIV pandemic and spread of drug resistant tuberculosis, mortality caused by tuberculosis (TB) has increased. To control the disease it is essential to identify the sources of the infection and patterns of transmission. This becomes possible through using molecular epidemiology methods.
    Materials And Methods
    This research reviewed studies based on IS6110- restriction fragment length polymorphism (IS6110-RFLP) as a primary method to recognize the role of molecular epidemiology researches in managing TB in Iran. Within 1995-2015 all human population based studies which had use IS6110-RFLP as the primary method systematically reviewed.
    Results
    At the end, 11 articles were selected. The mean clustering rate obtained was 28.1%. The rate of recent transmission was variable from 2% to 49% and the mean value was determined 17%.
    Conclusion
    The studies revealed that in Iran both reactivation and recent transmission were significant in developing new cases of TB. Yet, reactivation plays greater role. If the matter is supervised insufficiently and carelessly, because of increasing rate of drug resistant TB, immigration of HIV infected individuals, TB especially drug resistant TB will be problematic in the near future.
    Keywords: Molecular epidemiology, Restriction Fragment Length Polymorphisms (RFLP), Tuberculosis, Transmission, Control, Iran}
  • عبدالحسن کاظمی، باقر انصاری، ژانت بلیک، ثریا محمودی *
    انسان همواره در طول دوره حیات خود به دنبال ایجاد شرایط بهتر زیستی بوده و در دهه های اخیر با پیشرفت بیوتکنولوژی، مهندسی ژنتیک، ژن درمانی و... و کاربردهای این علوم در زندگی روزمره، سعی کرده است که بر محدودیت های زیستی خود غلبه کند و توانایی های جدیدی بیابد. از طرف دیگر، هدف تمام قواعد حقوقی و ارزش های عرفی ناظر بر جامعه انسانی، حفظ کرامت انسان، تنظیم روابط اجتماعی افراد جامعه و در اوج آن رسیدن به عدالت و برابری است، اما آنچه در این میان حائز اهمیت است، پیشرفت و توسعه مهندسی ژنتیک و بیوتکنولوژی انسانی و به دنبال آن ایجاد انجمن فراانسان ها هم زمان با رشد علوم حوزه تخصصی بیوتکنولوژی در اوایل 1988 میلادی است که این انجمن، موضوع «اصلاح نژاد انسان» یا «به نژادی» و ایجاد «ابرانسان» یا نسل جدیدی از انسان به عنوان «نسل برتر» را مطرح نموده و توانایی های تکنیکی علومی، مانند بیوتکنولوژی، مهندسی ژنتیک، ژن درمانی را برای دستکاری ژنوم و ژن های انسانی برای ایجاد توانایی ها و خصوصیات حیاتی جدید را، دستاویز ضرورت و یا احتمال «به نژادی» برای نسل بشر قرار داده است، اما در مورد تفکرات و ایده های این انجمن و تبعات این افکار، متفکران و به ویژه پژوهشگران اخلاق زیستی ابراز نگرانی کرده اند، زیرا نشانه هایی مبنی بر تلاش جهت دگرگونی ماهیت انسانی از سوی این انجمن، توسط برخی متفکران، افراط گرایانه تلقی می شود به خصوص آنکه در عقاید «انجمن فراانسان ها» تعریف روشنی از مفاهیم مورد تاکید این انجمن ارائه نشده است. بررسی مطرح شدن دگرگونی ماهیت و کرامت انسان با رسوخ و کاربرد بیوتکنولوژی، مهندسی ژنتیک، ژن درمانی و... برای دستکاری ژنوم انسان و تغییر صفات ژنتیکی، حیاتی و فیزیولوژیک انسان و به تبع آن تغییر ماهیت انسان، تغییر مبانی و مفاهیم حقوق و آزادی های اساسی بشری، آینده جوامع انسانی و اقلیت های نژادی و امنیت انسانی با توجه به تفکرات بنیان گذاران انجمن فراانسان ها موضوع این نوشتار است، زیرا چیستی، مفهوم و ماهیت انسان و ارزش و حقوق اساسی انسان ها در طول تاریخ تمدن بشری، اهمیت قابل توجهی در همه فرهنگ های بشری داشته است و برای درک این مفهوم و تعمیق و اشاعه آن تلاش های فکری و علمی فراوانی در دوران های مختلف صورت گرفته است. بنابراین قابل درک است که جامعه بشری، نگرانی خود را در مورد مفاهیم، چشم اندازها و ادعاهای انجمن فراانسان ها ابراز نماید.
    در این مقاله، برای ورود به بحث ضروری است که چیستی، مفهوم و ماهیت انسان را در رویکردهای مختلف فلسفی مورد بررسی قرار گیرد و در ادامه و با شکل گیری شالوده بررسی، به فلسفه فراانسان ها، آینده جوامع انسانی، اقلیت های نژادی، امنیت انسانی و... در عصر فراانسانی و تحلیل اعلامیه این گروه خواهیم پرداخت.
    کلید واژگان: فرا انسان, کرامت انسانی, ماهیت بشر, حقوق و آزادی های اساسی}
    Abdolhassan Kazemi, Bagher Ansari, Janet Blake, Soraya Mahmoudi*
    Constantly, the man tried to make better condition over the period of his life and in recent decades, with advances in biotechnology, genetic engineering, gene therapy, etc. has been tried to overcome biological restrictions. On the other hand, the aim of all the legal rules and values that govern to society is protection of human dignity, regulation of social relationships of society members to achieve justice and equality. But what is important, is progress and development of genetic engineering and biotechnology and subsequently, establishment of transhumanism association in early 1988. This association considers the issue of "Modification of human race" or "Eugenic" and tries to create "Transhumanist" or new generation of humans as "Superior race"and achievements of biotechnology, genetic engineering and gene therapy for manipulation of human genome and gens is pretext for "Eugenic" of the human spices. Scholars, especially bioethicists, have expressed their concern about idea of this group, because attempts for transform of human nature in behalf of this association are excessive. In particular, there is no clear definition about concepts that they use and emphasize. In this article, Consideration of human nature transformation and human dignity that rose subsequently by uses of biotechnology, genetic engineering, gene therapy, etc. for manipulation of human genome, the principles and concepts of rights and fundamental freedoms, future of human societies, future of ethnic minorities and human security according to the ideas of transhumanism founders is necessary.
    Throughout human civilization history, concept and nature of human, values and basic rights of human had considerable importance at all cultures and for understanding of this concept, have been made scientific and thoughtful efforts at different times, so it is comprehensible that human society express its concern about concepts, perspectives and claims of trans humanism association. In this article, we consider concept and human nature in different approaches of philosophy. Then, we will discuss about transhumanism philosophy, future of human societies, ethnic minorities and human security in ttranshumanis era and analyze its declaration.
    Keywords: Transhumanism, Human Dignity, Human Nature, Fundamental Freedoms, Rights}
  • Abdolhassan Kazemi, Maryam Majidinia*, Abbasali Jaafari, Seyyed Amin Ayatollahi Mousavi, Ali Zarei Mahmoudabadi, Hossein Alikhah
    Background
    Otomycosis is a superficial fungal infection often involves the pinna and external auditory canal. It is a pathologic condition, with Candida and Aspergillus, the most common fungal species. It is common worldwide but more prevalent in tropical and subtropical countries.
    Objectives
    The aim of this study was to determine the etiologic agents and local epidemiologic pattern of otomycosis in northwest Iran.Patients and
    Methods
    A series of 140 patients with clinically symptomatic otomycosis were studied in 21 cities, towns, and villages throughout northwest Iran between 2009 and 2011. Clinical samples were collected by swabs and then assessed by mycological investigation.
    Results
    Otomycosis was diagnosed in 129 cases (92%, 76 male, 53 female) with the highest prevalence of cases occurring in males between 21 - 40 years of age. From an etiological point of view, 116 patients (90%, 21 - 40 years old) were infected by saprophytic mold and 9 patients (7%) were infected by yeast. Three cases (2%) involved dermatophytes, and in one case (1%) the subject was infected with Eurotium (the perfect stage of Aspergillus fumigatus). Aspergillus niger was the most common mold that was isolated, followed by A. flavus, A. fumigatus, Penicillium spp., Fusarium spp., and Rhizopus spp. A total of 2 yeasts belonging to genus Candida, C. albicans and C. tropicalis, were isolated.
    Conclusions
    Our study showed a high prevalence of otomycosis in the northwestern area of Iran. As such, proper diagnosis and treatment by aseptic techniques for this disease is urgently needed.
    Keywords: Otomycosis, Fungi, Yeasts, Aspergillus niger}
  • Homayoun Sadeghi-Bazargani, Saber Azami-Aghdash *, Abdolhassan Kazemi, Behrad Ziapour
    Background
    Bam earthquake was the most catastrophic natural disasters in recent years. The aim of this study was to review different aspects of crisis manage­ment during and after the catastrophic earthquake in Bam City, Iran.
    Methods
    Data needed for this systematic review were collected through search­ing PubMed, EMBASE and SID databases, for the period from 2003 to 2011. Keywords included earthquake, Iran and Bam earthquake. The data were summarized and were analyzed using Content Analysis.
    Results
    Out of 422 articles, 25 articles were included in the study. Crisis Manage­ment aspects and existing pitfalls were classified into seven categories including planning and organization, human resource management, management of logistics, international humanitarian aids, field performance of the military and security forces, health and medical service provision, and information manage­ment. Positive aspects and major pitfalls of crisis management have been introduced in all the mentioned categories.
    Conclusion
    The available evidence indicated poor crisis management during Bam earthquake that resulted in aggravating the losses as well as diminishing the effect of interventions. Thus, concerning the importance of different aspects of the crisis management and the high prevalence of disasters in Iran, the observed vulnerability in disaster management process should be addressed.
    Keywords: Catastrophic Earthquake, Crisis management, Health, Iran}
  • عبدالحسن کاظمی، ثریا محمودی*
    ژن ها «طلای سبز» عرصه ی بیوتکنولوژی به شمار می آیند. در حال حاضر، شرکت های چند ملیتی و دولت ها همه ی قاره ها را در جست وجوی این طلای سبز زیر پا می گذارند، به امید این که انسان هایی را با خصوصیت های بی نظیر ژنتیکی که می توانند در آینده به سرمایه تبدیل شوند، کشف کنند. اقتصاد نوین چهارچوبی مشخص برای آنالیز تکنولوژی تازه ای از منظر سودجویی به ما ارائه می-کند، مفهوم سرمایه و بازار را دگرگون می سازد و بنابراین انسان ها یا هر موجود زنده ی دارای ویژگی های ژنتیکی خاص، می توانند هم به سرمایه و هم بازاری بالفعل و بسیار سودآور تبدیل شوند. باری، ثبت منابع ژنتیکی و مالکیت آن، بدون توجه به مبانی ذاتی حقوق بشر بر جامعه تاثیر خواهد گذاشت و باعث نقض حقوق اساسی بشر، به ویژه افراد و گروه های آسیب پذیر در اجتماع، خواهد شد و لذا در کنار توجه به فواید گسترده ی بیوتکنولوژی، در زندگی و سلامت افراد و جامعه ی بشری، نباید استفاده های سوء این فناوری ها را برای برابری، کرامت انسانی، سلامت، اتونومی، دسترسی به اطلاعات، به ویژه با واقعیت اتحاد میان تکنولوژی و قدرت-های اقتصادی نادیده گرفت. انقلاب بیوتکنولوژی می تواند باعث ادعاهایی مبنی بر مالکیت ذات حیات انسانی، صفات حیاتی و ژنتیکی توسط غیر شود و این همان مشکل عینی است که با وقوع انقلاب بیوتکنولوژی، در کشورهای در حال توسعه روی داده است و متعاقبا مردمان بومی این کشورها به چنین مسائلی واکنش های متفاوتی نشان داده اند.
    کلید واژگان: بیوتکنولوژی انسانی, کالاانگاری انسان, کرامت انسانی, اتونومی, مالکیت ژن}
    Abdolhassan Kazemi, Soraya Mahmoud *
    Genes are considered as “green gold” in this era of biotechnology. Currently، multinational companies and governments search continents to find this valuable asset in the hope to discover people with unique genetic characteristics that can be converted into capital and marketed in the future. Modern economy provides the framework to analyze any new technology from the advantage perspective and has vastly transformed the concept of capital and market; thus، humans or any organism with specific genetic characteristics can be converted to capital and offered in profitable markets. Patenting and ownership of genetic resources without consideration for principles of inherent human rights will impact the society and result in a violation of these rights، especially those of vulnerable individuals and groups. In spite of the numerous benefits of biotechnology for individuals and the society، the risks to human dignity، equality، health، autonomy and research، as well as the possibility of information abuse should not be ignored، especially considering the alliance between technology and economy. Biotechnology can make claims to ownership of human life and desired genetic traits، and this is a problem caused by the biotechnology revolution in developing countries and consequently، indigenous peoples of these countries have shown different reactions to such issues. This article will discuss “human commodification”، which is a serious concern in the field of biotechnology in our world today
    Keywords: human biotechnology, human commodification, human dignity, autonomy, ownership of genes}
  • Abdolhassan Kazemi, Alireza Ostadrahimi, Fereshteh Ashrafnejad*, Nafiseh Sargheini, Reza Mahdavi, Mohammadreza Farshchian, Sepideh Mahluji
    Background
    Nuts are one of the main consumed snacks worldwide and a significant component of Iranian’s diet. Natural contamination of nuts with fungus is unavoidable and is a major challenge to nuts safety and quality..
    Objectives
    The purpose of this research was to study fungal contamination in commercially available nuts (pistachios, walnuts and peanuts) in the markets of Tabriz, Iran..
    Materials And Methods
    100 samples of 50 gr roasted with salt peanuts and pistachios and 300 samples of 50 gr pure pistachios, walnuts and peanuts were collected from different areas of the local markets. After initial preparation, the samples were cultured on Sabouraud’s dextrose agar (SDA). 19 fungal isolates were identified..
    Results
    The results show that Aspergillus niger was the predominant mold among pure (44%) and roasted with salt (14%) nuts (P < 0/001). In addition, percentage of mycotoxigenic fungal contamination was 18% for roasted with salt nuts and 11% for pure samples..
    Conclusions
    The overall results of the analysed samples showed that the rate of fungal contamination in pure samples was higher than roasted with salt ones (P < 0.005). Results of the current survey could be useful for minimizing fungal contamination and can educate people about the dangers of mold in nuts..
    Keywords: Fungi, Nuts, Contamination, Aspergillus}
  • Alireza Ostadrahimi, Fereshteh Ashrafnejad, Abdolhassan Kazemi*, Nafiseh Sargheini, Reza Mahdavi, Mohammadreza Farshchian, Sepideh Mahluji
    Background
    Nuts are one of the main consumed snacks worldwide and also have an important role among Iranian''s food habits. Natural contamination of nuts with aflatoxin is unavoidable and causes a special challenge for nuts safety and quality.
    Objectives
    The purpose of this research was to study the aflatoxin contamination in commercially-available nuts (pistachio, walnut and peanut) in the markets of Tabriz, Iran.
    Materials And Methods
    Sixty two samples of 50 g salt-roasted peanuts and pistachios and 109 samples of 50 g pure pistachios, walnuts and peanuts were collected from different areas of local markets. After the initial preparations, ELISA test was performed for Aflatoxin measurement.
    Results
    Result showed that walnut (90%) and pure pistachio (2.3%) were the most and least contaminated samples, respectively. Mean aflatoxin contamination in the salt-roasted samples (19.88 ± 19.41 μg/kg) was significantly higher than the pure ones (6.51 ± 9.4 μg/kg) (P < 0.001). Respectively, 58.6%, 48.4% and 47.6% of salt-roasted pistachios, salt-roasted peanuts and walnut samples had aflatoxin contamination, which were more than the maximum tolerated level of Iran (MTL, 15 ppb).
    Conclusions
    It was concluded that aflatoxin content of nuts should be monitored regularly to minimize the risk of aflatoxin hazard and ensure the food safety and quality.
    Keywords: Aflatoxin, Nuts, Enzyme, Linked Immunosorbent Assay}
  • Abdolhassan Kazemi, Seyed, Amin Ayatollahi, Mousavi, Abbas Ali Jafari, Ali Zarei Mahmoudabadi, Hossein Alikhah
    Background
    Tinea versicolor is a superficial mycosis caused by Malassezia furfur, and is exclusively localized in the corneal layer of adults epidermis..
    Objectives
    To evaluate the epidemiological features of tinea versicolor, including its incidence among different age groups, genders and other personal status..
    Materials And Methods
    The study was conducted between 2009 and 2011 on 1023 patients who presented skin disease suspected to tinea versicolor. Of all patients; 671 females (66%) and 352 males (34%) were studied for this mycosis and the fungal distribution from the view point of age and anatomical region of mycosis were analyzed..
    Results
    The disease was more prevalent in 21-40 years old age group in both genders. The most infected anatomical regions were posterior surface, the body trunk (shoulder, supra scapula and lumbar region), anterior thorax and abdomen, respectively. The number of female cases was significantly more than males; this probably reflects the concern of females about their skin health..
    Conclusions
    Patients who regularly use the local saunas had poor personal hygiene and greasy skin, and were more suspected to tinea versicolor infection..
    Keywords: Tinea versicolor, Malassezia furfur, Malassezia globosa, Mycosis}
  • Mitra Mehrabani, Abdolhassan Kazemi *, Seyyed Amin Ayatollahi Mousavi, Mehdi Rezaifar, Hossein Alikhah, Akram Nosky
    Background

    Myrtus communis L. is an evergreen perennial shrub belonging to the Myrtaceae family that is spontaneously growing throughout the Mediterranean area. Myrtle has demonstrated important antimicrobial and antifungal activities to treat bacterial and fungal diseases.

    Objectives

    This study was aimed to develop a new method to evaluate the anti-fungal activity of hydroalcoholic extracts of Myrtle on dermatophytes by bioautography.

    Materials And Methods

    The species used for this study were: Microsporum canis, M. gypseum and Trichophyton mentagrophytes. The fungi were kept on Sabouraud dextrose agar (SDA) slants at 4°C and subcultured monthly throughout this study. Various fractions were prepared from hydroalcoholic extracts based on polarity. The antifungal assay of different solvent extracts was performed by agar disc diffusion method. A thin layer chromatography (TLC) method was developed to carry out bioautography TLC, the same solvent system as that of bioautography was used.

    Results

    Ethyl acetate and total methanolic extracts respectively had the best antifungal effects against three tested genera of dermatophytes. The ethyl acetate extract and methanolic extract that had the most inhibitory effect compared with any other fractions, were separated by solvent system (trifluroacetic acid, ethyl acetate, methanol, water: 0.1: 10: 0.04: 0.04) by TLC method. The best antifungal effects of the three fungi extracts was obtained in Rf: 0 - 0.3.

    Conclusions

    The active compound may be a flavonoid. Existence of flavonoids in tested fractions could be the important medicinal properties of M. communis leaves. Further work is required to evaluate the exact effect of these biological compounds on animal model or human volunteers.

    Keywords: Myrtus communis L., Antifungal Activity, Thin Layer Chromatography, Bioautography, Dermatophytes}
  • حسین ابراهیمی، عبدالحسن کاظمی، محمد اصغری جعفرآبادی، آرزو آزرم *

    یکی از پدیده های مهم در اخلاق پرستاری، تنش اخلاقی است. تنش اخلاقی که پرستاران از آن رنج می برند، یکی از شدیدترین مشکلات روان شناختی است. هدف این مطالعه تعیین تنش اخلاقی از دیدگاه پرستاران شاغل در بیمارستان های آموزشی شمال غرب ایران است. این مطالعه از نوع توصیفی- تحلیلی است که در آن 418 نفر از پرستاران شاغل در مراکز آموزشی درمانی در شمال غرب کشور در سال 1391 به روش نمونه گیری تصادفی چند مرحله ای شرکت نمودند برای جمع آوری داده ها از مقیاس استاندارد تنش اخلاقی (MDS) با روایی بالا استفاده گردید. برای تجزیه و تحلیل نتایج از روش های آمار توصیفی (میانگین، انحراف معیار، فراوانی و درصد) و آمار استنباطی (آزمون تی مستقل و آنالیز واریانس یک طرفه) استفاده شد.میانگین تنش اخلاقی کلی پرستاران مراکز آموزشی - درمانی شمال غرب کشور 49/148 (انحراف معیار = 93/32) بود و 222 نفر (53 درصد) از پرستاران تنش اخلاقی در سطح شدید داشتند. در بین سه استان، استان زنجان با میانگین 46/152 (انحراف معیار 88/35)، بالاترین میزان تنش اخلاقی و در بین بخش ها، بخش مراقبت های ویژه با میانگین 72/152 (انحراف معیار 36/33) بالاترین میزان تنش اخلاقی را داشت. از بین متغیرهای مشخصات فردی - اجتماعی پرستاران، استان محل خدمت (01/0P<)، تحصیلات (05/0 P<)، نوع نوبت کاری(05/0P<) و وضعیت شغلی (05/0P <) با میزان تنش اخلاقی ارتباط معنی داری داشت.با توجه به تنش اخلاقی بالا در حرفه ی پرستاری، مقابله با تنش اخلاقی توجه زیادی می طلبد. انجام مطالعاتی در مورد عوامل موثر و پیشگویی کننده ی تنش اخلاقی در بخش های مختلف و آموزش در مورد راهکارهای مقابله با آن ضروری است.

    کلید واژگان: تنش اخلاقی, پرستاری, اخلاق پرستاری}
    Hossein Ebrahimi, Abdolhassan Kazemi, Mohammad Asghari Jafarabadi, Arezo Azarm

    One of the most important issues in nursing ethics is moral distress، which is a severe psychological problem among nurses. The purpose of this study was to determine the nurses’ moral distress in the hospitals of the northwest of Iran. This was a cross-sectional study in which 418 nurses were selected by randomized multistep sampling method in the northwest of Iran in 2012. Data collection was done using the moral distress standard scale with high reliability and validity. In order to analyze data، descriptive (mean، standard deviation، frequency and percent) and inferential statistics (independent t-test and one way ANOVA) were used. The mean score of nurses’ moral distress was 148. 49 ± 32. 93، and 222 nurses (53%) suffered from severe moral distress. Of the three provinces under study، Zanjan (152. 46 ± 35. 88) and intensive care units (152. 72 ± 33. 36) had the highest moral distress scores. Among the respondents’ demographic characteristics، province (P < 0. 01)، education (P < 0. 05)، type of shift (P < 0. 05) and job status (P < 0. 05) were significantly related to the level of moral distress experienced by the nurses. Due to the high level of moral distress in the nursing profession، dealing with it requires a lot of attention. Studies on casual and predictive factors in different wards and teaching coping strategies to nurses appear to be necessary in order to address this issue.

    Keywords: ethics, moral distress, nurses, nursing ethics}
  • Abdolhassan Kazemi, Ehssan Ahmadpour, Behroz Naghili, Ali Zarei Mahmoudabadi, Abbasali Jafari *, Amin Mousavi Ayatollahi
    Background
    Air contamination with fungal spores and the presence of these spores on respiratory tract, especially in industrialized cities with contaminated air, can play an important role on the occurrence of respiratory and coetaneous mycoses, asthma and allergic reactions. This survey was carried out to determine the prevalence of different fungal spores in the atmosphere of Tabriz district..
    Objectives
    The present study aimed to detect fungal air spores in Tabriz environments, and to compare the environmental samples of Aspergillus fumigatus with the clinical isolated samples of this fungus, due to the importance of the dangers of A. fumigatus for public health, particularly for the immunocompromised patients..
    Materials And Methods
    During this survey, the presence of air fungal spores was analyzed using settle plate and prepared culture in Sabouraud’s dextrose agar. Prior identifications were performed using macroscopic characters, and direct microscopy. 262 samples were collected from different areas of the atmosphere of Tabriz district within all four seasons of the year. Fungal colonies were isolated from all air samples and identified using macroscopic and microscopic characters, and slid culture..
    Results
    The main isolated fungal spores from the atmosphere of Tabriz district were Penicillium Sp., (36.6%), Cladosporidium Sp., (26.8%) and Aspergillus Sp., (23.6%)..
    Conclusions
    The presence of fungal spores in the atmosphere as a part of air pollution can cause significant problems for human health, particularly in the respiratory tracts..
    Keywords: Fungi, Spores, Fungal, Tabriz, Aspergillus fumigatus}
  • Abdolhassan Kazemi, Mehraban Falahati, Ashraf Hajipoor, Abbasali Jafari, Mohammad Asghar Zadeh
    Background
    Fungal vaginitis originates from yeasts that are active in the mucosa of the women‘s genital tract. The main yeast that causes fungal vaginitis is Candida albicans.
    Objectives
    The current study aimed to detect frequency of yeasts mainly C. albicans in vaginal specimens of women from Tabriz, Iran. For the above purpose, the sensitivity and specifity of traditional laboratory assays were compared with those of molecular method (PCR) by universal and species primers to detect C. albicans in vaginal samples.Patients and
    Methods
    In this study, 250 vaginal specimens were collected from women in Tabriz, East Azerbaijan province, Iran during 2009- 2010. Samples were examined to identify C. albicans by germ-tube test, chlamydoconidium formation test, preparation of wet smear using potassium hydroxide, and Polymerase Chain Reaction (PCR).
    Results
    162 yeast species from 250 specimens were isolated in Sabroud Dextrose Agar (SDA) Medium. 106 (65.4%) of them were germ tube formation positive, 86 (53%) chlamydoconidium formation positive and 101(62.4%) were PCR positive. Yeast cells and mycelia were detected in the isolates on direct microscopic examination. C. albicans accounted for 66.04% of cases and 34% were non-C. albicans species.
    Conclusions
    In conclusion, PCR may be the best method to detect Candida species.
    Keywords: Candida Albicans, Polymerase Chain Reaction}
  • Mehrdad Asghari, Abdolhassan Kazemi, Mahasti Alizadeh, Siamak Heidarzadeh, Farhad Asghari, Hossein Safari, Mohammad Mahdi Bagheri, Asl
    Background
    By the development of E-learning in the world and also in Iran, Tabriz University of Medical Science has been implementing and expanding E-learning. The investigation of its problems from the academic staffs’ viewpoints, and proposing solutions in order to solve or eliminate the problem effects add to its advantages and provide sustainable basis according to the necessity of changing traditional education toward E-learning.
    Methods
    The present research is a descriptive study and the population under investigation involves the academic staff of Tabriz University of Medical Sciences who were selected randomly. The Validity and reliability of the questionnaires were evaluated and SPSS.15 software was used in order to analyze the data.
    Results
    Problems were classified into six approaches and twenty-four cases. The average of the administrative approach scores was 13.18±1.96, electronic approach 11.66±2.32, educational approach 13.39±2.22, economical approach 9.62±2.09, cultural and psychological approaches 20.43±2.53 and finally social and cooperative approaches were calculated to be 10.09±1.97.
    Conclusions
    The teaching board members believe that they do not have enough time or skills for compiling and evaluating E-learning materials and there is no proper culture for this, the attitude should be changed. Finally not only should the professors learn how to compile, use and to take rapid feedback, but it is also essential that they recognize their new roles (as learning facilitators) in realizing and expanding their mode of education, by their imaginative creations. Of course attendance of the professors without support of the universities and proper planning for enhancing the relationship between the professors and staff of information technology are not logical.
    Keywords: E, learning, Learning problems, Medical Education, Academic Staff}
  • عبدالحسن کاظمی، مصطفی کاظمی، نجات فیض اللهی، صدیار عطالو، رضا مسعودی فر، محمد مسعودی نیا، محمود عباسی، مهرزاد کیانی
    مقدمه
    با مشاهده اثر سیستم تلومر- تلومراز در افزایش طول عمر سلول ها و در مدل های آزمایشگاهی این فرضیه مطرح شده است که شاید با استفاده از این سیستم، از پیر شدن سلول ها جلوگیری و به تبع آن افزایش طول عمر را محقق کرد اما این موضوع بسیار پیچیده ای را به دنبال می آورد.
    مواد و روش ها
    تغییر در الگوی وقوع پیری و به تبع آن مرگ، تغییر هرم جمعیتی را به دنبال آورده، ضرورت سیستم سازی خاصی را در بودجه های بهداشتی، تخصیص امکانات، پرورش نیروی انسانی، ارائه خدمات و مراقبت ها و...ایجاب نموده و بروز پیری در افراد جامعه در صورت عدم وقوع مرگ بدنبال آن، تبعات وسیعی را در پی دارد و کل نظام اجتماعی، اقتصادی و ارزشی حامعه را به صورت وسیع تحت تاثیر خود قرار می دهد.
    یافته ها
    وقوع پیری و به دنبال آن وقوع مرگ، نقش تعیین کننده ای در زندگی و در تنظیم روابط اجتماعی به معنای اعم آن توزیع منابع قدرت و ثروت اجتماعی ایفا کرده است. بنابراین افزایش غیرمعمول طول عمر، مجموع روابط اجتماعی را به چارچوب های جدید و ناشناخته ای منتقل می نماید.
    نتیجه گیری
    اکنون توانایی های ویژه ای در دانش پزشکی و علوم پیرامونی آن برای افزایش طول عمر وجود دارد اما نگرانی های هزار تو و چند لایه ای نیز در مورد مسایل مابعد افزایش معنی دار طول عمر مثلا تبدیل گروه برخوردار از طول عمرهای بیشتر به یک نوع خاص و احیانا برجسته و مافوق انسان مطرح می کند.
    کلید واژگان: چالش اخلاقی, دستکاری ژنتیکی, طول عمر}
    Abdolhassan Kazemi, Mostafa Kazemi, Nejat Feizollahi, Sadyar Ataloo, Reza Masoudi Far, Mohammad Masoudi Nia, Mahmood Abbasi, Mehrzad Kiani
    Introduction
    By observing the effect of telomere and telomerase systems on the prolongation of the cells’ lives and in the laboratorial models this hypothesis has been raised that perhaps the aging of cells may be prevented and consequently the life prolongation may be realized by using this system; but this would be followed by a very complicated issue.
    Materials And Methods
    changing in the model of aging occurrence and therefore death has brought about the changing of the population pyramid and has required the necessity of a special systemization in the health budgets, allocation of resources, training of human resources, caring, etc. The occurrence of aging among the members of the society, in case of being followed by non-dying has wide implications and will affect the whole social, economical and appraisal system of the society on a large scale.
    Findings
    Occurrence of aging followed by death has played a decisive role in the life and the regulation of social relations, in its general sense the distribution of social power and wealth sources. Therefore, the uncommon increase of life span will transfer the total social relations to new unknown frameworks.
    Conclusion
    Now, there are particular abilities in the medicine and peripheral sciences for the life longevity.
    Keywords: Ethical challenge, genetic manipulation, longevity}
  • Abbas Ali Jafari, Abbas Falah-Tafti, Mohammad Hossein Lotfi-Kamran, Arezzo Zahraeii, Abdolhassan Kazemi
    Background
    Adherence of Candida species, mainly C. albicans to denture surfaces, forms a biofilm which causes denture stomatitis in denture users. Removal of Candida plaque on dentures is essential to control the colonization of this yeast and to prevent infections related to C. albicans.
    Objectives
    The aim of this study was to compare the effectiveness of sodium hypochlorite with white vinegar for the disinfection of C. albicans from acrylic resin.
    Materials And Methods
    82, 10×10×1 mm acrylic resin plates were inoculated with 1×103 C. albicans suspension for 24 hours to prepare experimental Candida biofilm. The total number of Candida cells which adhered to 10 acryl resin plates was determined and the remaining 72 plates were randomly divided into four groups. The test plates were immersed in a solution of 1% sodium hypochlorite, 5% or 10%white vinegar for a period of 8 hours and distilled water was used as the negative control group. The Candida removing ability of the 3 disinfectants and the negative control group was assessed by comparing the number of colony forming units per 1 mL of the plates washing solution before and after the removing protocol. Data was analyzed using Kruskal-Wallis and Mann-Whitney tests.
    Results
    Sodium hypochlorite (1%) and white vinegar (10%) removed 100% of the C. albicans cells, followed by white vinegar (5%), which removed 99% of the adhered C. albicans from the acrylic resin plates. There wasn’t any significant statistical difference found between the 5% and 10% white vinegar in removing Candida from the acryl resin plates (P = 0.161).
    Conclusions
    Overnight immersion of complete removable dentures in 10% or even a 5% white vinegar solution effectively removed C. albicans cells that had adhered to the denture surface and their removal properties the same as 1% sodium hypochlorite
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