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Diabetes is a metabolic syndrome that is increasingly globalized. Many studies are currently focused on the anti-hyperglycemic effects of safe and harmful herbal products including cinnamon. This study was conducted to investigate the effect of cinnamon on blood glucose, HbA1C, and insulin resistance in type 2 diabetic patients because of inconsistency in the results of previous studies.

This double blind randomized clinical trial was performed on 69 male and female diabetic patients with mean fasting blood glucose level of 202.16 ± 44.30 in Zahedan, Iran. Subjects were divided into three groups (two groups receiving cinnamon recipients with doses of 2 and 4 g and control group). Subjects received 4 capsules daily for 12 weeks. After 8 hours of fasting, blood samples were taken at the beginning of the intervention and weeks 4, 8 and 12 were measured to measure fasting blood glucose, insulin resistance and HbA1c. One-way ANOVA and Repeated Measurement and SPSS software were used to analyze the data.

At the end of week 8 and 12, a statistically significant decrease in mean fasting blood glucose, HbA1C and insulin resistance was observed in the experimental groups (Cinnamon 2 and 4 g daily) compared to the control group (P <0.001). Also at the end of week 12, the glucose and HbA1C variables were significantly different between the two experimental groups receiving cinnamon (P <0.001).

Long-term consumption of high-dose cinnamon is effective as a low-risk supplement for controlling blood glucose and improving the health of people with diabetes.

Metabolic syndrome is increasing with progressive syrup in all age groups. It has become a serious health problem in the community. Today, a number of researches have focused on determining the anti-fat effects of cheap and highly safe herbal products. Cinnamon, one of these herbs, has the ability to lower blood lipids due to its cinnamaldehyde element. Hence, the aim of this study was to determine the effect of cinnamon in different doses on cholesterol, triglyceride, LDL and HDL levels in diabetic patients.

This double-blind randomized clinical trial was performed on 69 male and female diabetic patients with mean blood triglyceride level of 179.91 ± 14.19 in Zahedan. Subjects were divided into 3 groups (2 intervention groups receiving cinnamon 2 and 4 g doses and control group receiving placebo). Each subject received 4 capsules daily for 12 weeks. Intravenous blood samples were taken to measure cholesterol, triglyceride, LDL, HDL and FBS at baseline and at 4, 8 and 12 weeks. One-way ANOVA and Repeated Measurement tests were used for data analysis

There was a statistically significant decrease in mean triglyceride, cholesterol, glucose and LDL levels in the intervention group compared to the placebo group (P <0.001). There was no statistically significant difference in mean HDL between the three groups (P >0.05).

Long-term consumption of high-dose cinnamon can be effective in reducing the lipid profiles of diabetic patients because of its polyphenolic compounds.