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The aim was to assess prevalence of tinnitus, hyperacusis, hearing and balance problems among patients recovered from COVID-19 infection. Self-reported ear and hearing symptoms were compared in three groups comprising: confirmed COVID-19, possible COVID-19, and non-COVID-19. 1649 participants completed the survey in this cross-sectional study. The mean age was 34 years and 65% were female. Participants with confirmed and possible COVID-19 were asked if after their infection (compared to the past) they experienced hearing loss, ringing or whistling noises, fullness or blockage in their ears, loudness of the sounds that are normal to other people bother them more (an indication of hyperacusis), dizziness, giddiness, or imbalance.  Among participants with confirmed COVID-19, 16% reported that compared to the past their hearing has decreased, 21.5% noticed tinnitus, 22.5% aural fullness, 26.1% hyperacusis and 17.3% balance problems. Regression models showed that compared to the non-COVID-19 group, participants with confirmed COVID-19 had odds ratios (ORs) of significantly greater than 1 in predicting presence of self-reported symptoms of hearing loss, tinnitus, aural fullness, hyperacusis and balance problems, OR=1.96 (p=0.001), OR=1.63 (p=0.003), OR=1.8 (p<0.001), OR=2.2 (p<0.001), and OR=2.99 (p<0.001), respectively. There seem to be higher prevalence of self-report symptoms of ear-related problems among individuals with confirmed COVID-19 infection compared to a non-COVID-19 group during the pandemic.

This study aimed to compare the effectiveness of  SNAPPS and an integrated model of outpatient education in developing clinical competencies of clerkship students concerning infectious diseases.

This study has a quasi-experimental design (pretest, posttest, control group). The experimental and control groups were selected without random placement. The experimental group was trained using the integrated model, whereas the controls were trained with the SNAPPS model. After the data were collected, the test results were analyzed  in the three areas of Knowledg, clinical reasoning, and skills using the Wilcoxon test, Mann-Whitney U test, and paired t-test.

The mean within-group score changes were significant in both groups concerning clinical reasoning, skills, and cognition. The cognition mean scores in the integrated and SNAPPS models were 18.94 and 18.06, respectively, with a significant difference between the two models (P=0.029). However, there were no significant differences between the groups concerning the mean scores of clinical reasoning (p=0.425) and skills (p=0.092).

The integrated model outperformed SNAPPS in increasing the knowledge, clinical reasoning,and skills of clerkship students.

Green Human Resource Management is a comprehensive approach in todaychr('39')s organization and management, especially in the last decade, which has been met with great success in the scientific and industrial communities. In the Petroleum industry, the use of green human resources has become a strategic tool for achieving sustainable competitive advantage. So, this study intended to identify and prioritize the obstacles to the implementation of green human resource management. An expert questionnaire was used to collect research data. The statistical population of this study included managers and experts with a history of Tehran Oil Refining Company (TORC). The ANP and DEMATEL algorithms were used as research tools. The results showed that individual factors are the main obstacles in the implementation of green human resource management and infrastructural and cross-organizational barriers are also of great importance.

In this study, the relationship between supply chain management functions, supply chain performance, competitive advantage, and organizational performance in the hospitality were investigated. The objective of this study was to assess the performance of supply chains and management in the hospitality. For this purpose, a model consisting of 4 variables and 5 hypotheses was created. The statistical population of this study included all administrative staff of the 4 and 5-star hotels in Tehran. Sampling among senior and middle managers was done randomly. A total of 199 samples were collected and the designed model was tested using a structural equation approach. All study hypotheses were approved. The results indicated that using the dimensions of the supply chain management function, we can observe the positive and comprehensive impact of these factors on organizational performance, supply chain performance, and competitive advantage. In addition, supply chain performance and competitive advantage were found to have a positive and significant effect on organizational performance.

A breeding hexaploid wheat line named later Rakhshan was introduced to Iran through the CIMMYT 41th-IBWSN international nursery with pedigree of " SHARP/3/PRL/SARA//TSI/VEE#5/5/VEE/LIRA//BOW/3/BCN/4/KAUZ " in 2008. This line showed average grain yield of 9019 kg/ha compared to check cultivars Pishtaz, Shiraz, Marvdasht and Bahar average with 9060 kg/ha in Karaj, Kermanshah and Zarghan during 2008-09 crop season. This genotype showed grain yield of 8710 kg/ha compared to 7910 kg/ha of four check cultivars: Parsi, Sivand, Bahar and Pishtaz in Karaj, Zarghan, Neishabour, Isfahan and Islam Abad-Gharb during 2009-10. This line was tested in advanced and replicated trials over same 5 locations at 2010-2011 with recorded grain yield of more than 7 t/ha and measured good bread making quality. The adaptation and stability of this line was evaluated in a 2 years' experiment tested over 8 stations during 2011-13 period which recorded grain yield of 7.695 t/ha against 7.582 of Parsi and 7.547 t/ha of Sivand. During testing of this variety under on-farm and demonstrational trials in farmer fields during 2013-15 over several locations of temperate zone under normal irrigation conditions, average grain yield of 8.233 t/ha against 7.734 t/ha of Parsi cultivar was recorded. It showed also potential of 10.116 and 11.290 t/ha grain yields in Kermanshah and Alborz provinces respectively. According to the final investigations, reaction of Rakhshan to yellow rust and leaf rust was recorded as 0 to 30MS in the inoculated nurseries. In case of stem rust race Ug99 reaction was 40MR in Kenya. Bread making quality of this variety is good and it is relatively an early maturity variety.

The purpose of this paper is to analyze manufacturing networks and supply chains from an operations strategy perspective. These two areas have traditionally been treated as separate research tracks, but with the ongoing globalization of markets and operations there is a need to integrate these complementary disciplines to study networks of facilities. In this paper we examine the two research areas based on two structural decision categories in an operations strategy, i.e., facilities and vertical integration. We present a typology for the analysis of network systems resulting in four basic network configurations. Coordination of activities within the network is contingent upon the configuration, thus resulting in four coordination approaches. The configuration and coordination analysis can be used as a foundation for further research in the context of integrating anufacturing network and supply chain theory.

The aim of this study is to examine the relationships between SCQM practices, performance and innovation. A conceptual model is developed and tested through path analysis using the cross-section data collected from the automotive industry in Iran. Using a quantitative methodology, 280 of 500 senior and executive managers in the automotive industry in Iran participated and completed the survey. Exploratory factor analysis (EFA) was used for data reduction of the entire sample (to purify the scale) and to ascertain whether the survey questions were loaded on their respective dimensions (this was refined and confirmed later by CFA). Besides that, the Structural Equation Modeling (SEM) was used to examine the research hypotheses and hypothesized model. The findings support the positive effect of the supply chain quality management practices on innovation and organizational performance. In addition, the results of the analysis also suggest that innovation partially mediates the relationship between supply chain quality management practices and organizational performance. Moreover, this study makes several theoretical and empirical contributions and provides further insights on SCQM practices. Managerial implications are discussed, as well as several potential recommendations for future studies are identified and a conclusion is drawn. The outcomes of this research would enable managers to assess the strengths and weaknesses of their organizations and thus develop appropriate strategies to improve their organizational performance.

In the treatment of bipolar disorder in youths, often more than one medication should be prescribed. In the current study, we compared the efficacy and tolerability of the combination of lithium and quetiapine with lithium and risperidone in the treatment of manic or mixed episodes in children and adolescents.
Thirty patients (aged 10-18 years) who were hospitalized for a manic or mixed episode were recruited from consecutive inpatient admissions to the Child and Adolescent Psychiatric Unit at Razi Psychiatric Hospital (University of Social Welfare and Rehabilitation Sciences, Tehran, Iran) from June 2012 to September. They were randomly treated with lithium (with the usual dose to achieve blood levels 0.8-1) and quetiapine (400-600 mg per day) or risperidone (0.5-6 mg per day). The primary outcome measure with respect to efficacy was the mean decrease in Young Mania Rating Scale (YMRS) score. Side effects were also assessed. The independent t test and two-factor repeated measure analysis of variance (ANOVA) was used for data analysis. P-value of less than 0.05 was considered statistically significant.
The reduction in YMRS scores was similar in both groups. The remission rate (YMRS Both protocols were effective. Quetiapine in combination with lithium in manic or mixed episodes of bipolar I disorder in children and adolescents was not superior to lithium and risperidone, but was associated with fewer complications.

Supplier selection and allocating orders to them accurately, is one of the most important challenges in supply chain management.The reasone is that an incorrect choosing suppliers can disrupt the financial and technical position of supply chain. Whereas the supplier selection is a multi-objective decision making with multiple criteria problem, in this paper a linear multi-objective mathematical programming model is presented. In this model, Analytic Hierarchy Process (AHP) has been used for determining supplier’s priority (weight). By choosing proper evaluation criteria, appropriate number of suppliers and suitable amount of row material orders from each supplier can be specified. The presented model is a mathematical programming model that includes five objective functions and several contraints. Epsilon constraint method is applied to solve the model using a pharmaceutical company data. Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) has carried out to determine the best answer Among Pareto solutions. The results of numerical example and sensitivity analysis show the applicability of the suggested model.

This paper develops an operational perspective of supply chain sustainability, by considering it as a risk management process. It explores the nature of sustainability-related supply chain risks, distinguishes them from typical supply chain risks and develops an analytical process for their management. An empirical study is conducted to generate insights about how sustainability-related risks should be managed in an integrated way. A mixed method approach is adopted for data collection and analysis. Through an extensive literature review and personal interviews, 30 risks across the three main pillars of sustainability (environmental, social and economic) are identified first. A large survey across different industrial sectors and two exploratory empirical case studies in two textile manufacturing companies are subsequently conducted to assess and analyses several dimensions of sustainability-related risk. The failure mode and effect analysis (FMEA) technique is utilized to assess the relative importance of the selected risks, to identify their potential causes and effects and test potential correlations between the identified risks. Based on the findings of the study, risk treatment strategies are proposed for all the identified sustainability-related supply chain risks. The findings show that endogenous environmental risks are perceived to be the most important across different industries and the interconnectedness between several sustainability-related risks is very high. This points to the need for integrated sustainability risk management approaches to facilitate the development of effective sustainable strategies.

This study proposed to the new concept of warehouse management and the of diversity and number of storage on warehouses management in the Kayson project-based company is influenced. For this purpose, the certain structural model from the perspective of the employees in the company's warehouses of Kayson will be analyzed. Survey-based applied research and methods of structural equation modeling is used in the survey. The required data through questionnaires from a sample of 152 employees of the company's warehouses is Kayson the cluster sampling was collected. Cranach’s alpha and composite reliability, the reliability of the questionnaire were to the right. The test model with partial least squares method and correlation test was performed with the use of SMART-PLS software. Test results show that in the first warehouse management and multiple storage warehouses with a variety of items at the corporate level and the project has a significant relationship, diversity also features warehouse information system, the complexity of the legislation, extensive planning and management skills are related. Finally, the number of stock at the corporate level and extensive project planning and management skills significant relationship and correlation tests also confirm this relationship.

Valproic acid is widely used as an anticonvulsant and mood-stabilizing drug in the treatment of epilepsy. Determination of serum valproic acid is required in epilepsy therapy for efficient control of seizures.. In the present study, the gas chromatography method was applied to determine serum valproic acid and resulting data were compared with those obtained by high performance liquid chromatography.. Two methods were used: assayed patients'' serum samples and serum quality control materials for laboratory diagnostics applied to high performance liquid chromatography (HPLC)and gas chromatography (GC). All chemicals had a grade suitable for analysis.. The obtained results in both systems were in agreement regarding linearity, correlation and recovery. The results revealed a lower GC limit of quantification (8 µg/mL), a better intra-assay coefficient of variation (CV) (3.86% - 3.99%) and inter-assay CV (6.14% - 6.42%) for all three levels of control materials. In addition, a shorter run time of the GC vs. the HPLC chromatographic step (6 minutes vs. 17 minutes) was observed.. The present study reports a short run time of the chromatographic step as well as a good sensitivity for the GC method. Furthermore, the significance of this method is the simplicity in sample preparation step without the need for derivatization and specific detector ensuring cost-effectiveness for the GC analysis. In summary, in comparison with HPLC method, our obtained data illustrate a good performance of the GC analytical procedure and confirm its usefulness for the routine quantification of valproic acid level in patients'' serum specimens..

Valproic acid is widely used as an anticonvulsant and mood-stabilizing drug in the treatment of epilepsy. Determination of serum valproic acid is required in epilepsy therapy for efficient control of seizures.. In the present study, the gas chromatography method was applied to determine serum valproic acid and resulting data were compared with those obtained by high performance liquid chromatography.. Two methods were used: assayed patients'' serum samples and serum quality control materials for laboratory diagnostics applied to high performance liquid chromatography (HPLC)and gas chromatography (GC). All chemicals had a grade suitable for analysis.. The obtained results in both systems were in agreement regarding linearity, correlation and recovery. The results revealed a lower GC limit of quantification (8 µg/mL), a better intra-assay coefficient of variation (CV) (3.86% - 3.99%) and inter-assay CV (6.14% - 6.42%) for all three levels of control materials. In addition, a shorter run time of the GC vs. the HPLC chromatographic step (6 minutes vs. 17 minutes) was observed.. The present study reports a short run time of the chromatographic step as well as a good sensitivity for the GC method. Furthermore, the significance of this method is the simplicity in sample preparation step without the need for derivatization and specific detector ensuring cost-effectiveness for the GC analysis. In summary, in comparison with HPLC method, our obtained data illustrate a good performance of the GC analytical procedure and confirm its usefulness for the routine quantification of valproic acid level in patients'' serum specimens..

The purpose of this study was to evaluate the effect of adjunctive topiramate in treating acute mania. In this study which was a double-blinded randomized clinical trial, 46 bipolar patients in manic episode, were treated with lithium carbonate and topiramate versus lithium carbonate and placebo and treatment responses were assessed by Young Mania Rating Scale (YMRS) weekly. In both intervention and control groups, YMRS score had significant decline after 8 weeks (p < 0.001), but there was no statistically significant difference between the two groups (p = 0.419). The highest score decline was after two weeks. YMRS score at baseline did not have statistically significant difference between the intervention and control groups (p = 0.709). This study failed to show antimanic efficacy of adjunctive topiramate in the treatment of those with acute manic

In the present research، the effect of skin pass rolling on work hardening coefficient and normal anisotropy، representing deep drawability in sheet metals ecpecifically in automotive industries، are investigated. To do this، several samples of low carbon steel sheets were selected and the effect of cold reduction on and and grain morphologies was studied. The results showd that cold reduction less than 4. 8% and also elongation magnitude of skin pass do not affect on value. On the other hand، severely decreases with cold reduction and elongation percent of skin pass. The amount of decrease depends upon microstructure and process conditions of prior skin pass stages.

the researches showed which drug treatment had various effects on individual's sexual function.The purpose of study was to survey effects of protector treatment with methadone in sexual function in men that dependent to opiates. This study is a quasi-experimental study. Studistical population was married men that dependent to narcotics and have been under of treatment protector with methadone. The sample consists of 69 people which selected with available sampling method. The questionnairs were used consist of demographic questionnaire and sexual functional questionnaire (SFQ). the sexual function has increased in overall sexual performance and the sexual desire after start of treatment. also there was no meaningful statistically difference between erection and ejaculation in sample of study before and after of the treatment. Protector treatment with methadone can be effective in sexual function in people dependent to opiates.