فهرست مطالب amir pooyan tabibi

There are controversial evidences on the association between fingerprint traits and schizophrenia. We compared fingerprint traits of patients with schizophrenia and normal individuals in Iranian population. Fingertip dermal ridge of 290 patients with schizophrenia and 290 normal subjects were studied for four dermal traits. Data was analyzed with Pearson correlation and t-student tests. Fingerprint patterns and secondary creases were not significantly different between the two groups (p > 0.05). Although mean ridge counts of left and right index fingers in the case group were greater than the control group (p < 0.05), the difference was not significant in females. Probably left index ridge counts and fluctuating asymmetry in schizophrenic patients are different from those of the normal population. This difference may serve as a diagnostic biological marker for screening people susceptible to schizophrenia. Further studies are needed to determine the predictive value of fingerprint trait as a schizophrenia biomarker.

Environmental fungi, molds and yeasts, can infest the nasal cavity through inhaled air. There is some evidence that they could be the main cause of Chronic Rhino-Sinusitis (CRS) but little is known about the normal fungal flora in the human nose.The objective of this study was to assess the normal fungal flora of the nasal mucus in adults in Kerman. We conducted a cross sectional study. Nasal swabs were used to sample the nasal cavity of 100 adults, 46 men and 54 women between 17 and 60 years old, currently living in Kerman, Iran. Among 100 healthy people, one or more types of fungi were detected in 31 (31%) persons; Candida in 12 persons, Aspergillus in 8 persons, Streptomyces in 8 persons, and Penicillium, Nocardia and Mucor in a few persons. In only 4 persons, more than one type of fungi was detected. There was no significant relation between age, sex, education or smoking with the presence of fungi.

To review Her-2/neu and Tp53 status and their correlation with all other prognostic clinicopathologic features of infiltrative ductal breast carcinomas. This cross sectional study was performed on 139 patients with infiltrative ductal breast carcinoma who were diagnosed between May 2000 and March 2006 at the surgery and pathology departments of Alzahra Hospital, Isfahan, Iran. Immunostaining (IHC) for Tp53 and Her-2/neu were performed on formalin-fixed, paraffin-embedded tissues based on an avidin-biotinperoxidase complex technique. The relationship of these markers with clinicpathologic parameters including age, axillary lymph nodes status, tumor size and histological grade were evaluated. It was found out that Her-2/neu-positive cases were greater among metastatic lymph nodes than in patients without metastasis, however it was not significant (p=0.1). A significant association was also observed between Her-2/neu status and tumor grading (p=0.01). On the contrary, no association was found with other clinicpathologic parameters. In this study, Tp53 presentation in high-grade carcinomas was significantly more as compared to low grade ones (p=0.03). A significant association was also observed between Tp53 and tumor size (p =0.01). There was no association with menopausal status and lymph node status. IHC determined that Her-2/neu and Tp53 expressions are not associated with nodal and menopause status. Conversely, a correlation was found between Her-2/neu, Tp53 expressions and high histological grade of tumor. However, to validate these findings, long-term prospective studies on patients’ survival are necessary.