فهرست مطالب arash tabei
-
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were prepared by condensation of corresponding hydrazides 7 and 8with different aldehydes 9a-9e. The structures of all synthesized compounds were confirmed by means of FT-IR, 1H-NMR and Mass spectra. All compounds were evaluated for their analgesic activities by abdominal constriction test (writhing test). Most of the synthesized compounds induced significant reduction in the writhing response when compared to control and compound 15was more potent than mefenamic acid in the writhing test.Keywords: Hydrazide, Hydrazone, Analgesic activity, Fenamate}
-
A series of phenoxybenzylidene aroylhydrazine derivatives were synthesized and their structures were confirmed using FT-IR and 1H-NMR spectroscopy. Analgesic profiles of all compounds were examined using abdominal constriction test (writhing test). Most of synthesized compounds induced significant reduction in the writhing response as compared with controls. The most active compounds exhibited an analgesic activity comparable with that of mefenamic acid.Keywords: Hydrazine, Analgesic Activity, Fenamate, NSAIDs}
-
Synthesis of new 1.3-thiazoline - 2 - thiones as potential antimycobacterial agents
بدانید!
- در این صفحه نام مورد نظر در اسامی نویسندگان مقالات جستجو میشود. ممکن است نتایج شامل مطالب نویسندگان هم نام و حتی در رشتههای مختلف باشد.
- همه مقالات ترجمه فارسی یا انگلیسی ندارند پس ممکن است مقالاتی باشند که نام نویسنده مورد نظر شما به صورت معادل فارسی یا انگلیسی آن درج شده باشد. در صفحه جستجوی پیشرفته میتوانید همزمان نام فارسی و انگلیسی نویسنده را درج نمایید.
- در صورتی که میخواهید جستجو را با شرایط متفاوت تکرار کنید به صفحه جستجوی پیشرفته مطالب نشریات مراجعه کنید.