فهرست مطالب effat khorasani

This study aimed to investigate the prevalence of hyperglycemia stress in children referred to the pediatric emergency department in Neyshabur city in 2015.

This descriptive-cross-sectional prospective study was conducted on 1484 children referred to emergency department in Neyshabur city. Clinical biography involving fever, seizure, dehydration, abnormal respiration, and admission to ICUs were considered as an independent stress. Blood glucose measured using glucose oxidase, enzyme, which was analyzed using Pars Azmoon kits. In this study, ≥150 mg/dL blood sugar was considered as hyperglycemia. The data were coded and entered into SPSS software version 16 and analyzed using descriptive and inferential statistics.

In general, 79 patients (5.4%) had blood glucose greater than 150 mg/dL, that they were diagnosed with hyperglycemia. Also, 5.03% of children were identified with dehydration. There was a significant difference between the presence and absence of hyperglycemia and body temperature in children referred to the pediatric emergency department (χ2= 38.8) (P= 0.01).

Hyperglycemia stress is a common clinical event in patients referred to the emergency department. Although risk factor associated with hyperglycemic stress is not completely identified, there is a relationship between fever and dehydration with stress hyperglycemia

One of the most common metabolic diseases is diabetes mellitus (DM), which its prevalence is growing trend. Early diagnose peripheral neuropathy (DPN) in early stages of patients with DM contributes to metabolic control and prevents severe complications. We aimed to determine the prevalence of peripheral neuropathy (PN) and its related factor in Diabetic children.
This cross-sectional study was performed among 60 children with diabetes (type 1) who referring the pediatric endocrinology clinic of Hakim Hospital, Neyshabur city, Iran, in 2016. The neurological symptom score was used for the assessment of neurological features. Neuropathy disability score (NDS) was obtained from the examination of vibration perception (by means of a 128-Hz tuning fork). Peripheral vascular examination was also carried out via evaluating dorsalis pedis and posterior tibial pulses by a neurologist.
The mean age of the children was 10.8±3.38 years. About 56.2% of the patients were female. Diabetic peripheral neuropathy (DPN) score was moderate in 6.7% of the children and it was mild in 38.3% of them. In general, 23% of the children with hemoglobin A1C (HbA1c) higher than the normal range had PN. Assessment of the degree of DPN based on duration of diabetes showed a significant difference among the participants (P=0.05). The study of HbA1C rate based on different degrees of DPN showed a significant difference (P=0.001). In addition, we found a significant difference in FBS score between the children with DPN and children without it (P=0.01).
According the results, more than 23% of children with diabetes had DPN, and the duration of diabetes was a related factor in PN. Therefore, neurological assessment including nerve conduction studies and meticulous physical examination should be performed for evaluating the function of large sensory and motor fibers.

Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tissues. Resistance to thyroid hormone might be an important additional diagnosis to consider in cases where thyrotropin remains persistently elevated. In this article we described an infant with RTH; her situation was diagnosed incidentally at birth with impaired hypothyroidism screening tests.