فهرست مطالب faezeh khajavi

Bacterial leakage has considerable role in endodontic related failures. The aim of this study was to compare the bacterial leakage of bioceramic and resin based root canal sealers.

Sixty-eight maxillary central incisors were included in this experimental study and randomly allocated to four groups which obturated with GP and four different sealers (AH Plus=15, AdSeal=15, Well Root ST=15, MTA Fillapex=15) and control groups (positive =4, negative =4). A dual chamber technique was carried out using fresh human saliva and traced for 90 days. Chi-square and Long Rank test was performed for data analysis.

Bacterial leakage was observed in 33.3% of Well Root ST, 40% of AH Plus, 53.3% of AdSeal and 66.6% of MTA Fillapex group.  The difference between Well Root ST and MTA Fillapex groups was significant (P= 0.02). The mean leakage time between Well Root ST (85.6 days) and MTA Fillapex groups (71.2 days) was significant (P= 0.037).

Based on the result of this study, bacterial leakage was observed in all experimental groups.Respectively Well Root ST and MTA Fillapex groups showed the least and highest bacterial leakages.

Medicinal plants, such as flaxseeds play an important role in the health of individuals and communities. Regarding the phytochemical properties of flaxseed, this study aimed to investigate the hydroalcoholic effects of this plant on the genetic toxicity of cyclophosphamide in peripheral blood lymphocytes. The flaxseed extract was initially prepared by maceration using ethanol solvent in two rounds. After one hour of incubation with different concentrations, the blood samples were incubated with 750µ M in a bain-marie at 37° C for 24 h. To evaluate the production of micronucleus in dual nuclear lymphocytes suppressed in cytokines, the slides were prepared and evaluated using light microscopy. The data were analyzed in SPSS software and the mean values were compared using Tukey's test and.
Ethics code: 30.96.3.1002 The incubation of blood samples with cyclophosphamide leads to induced additional genotoxicity in lymphocytes. Moreover, flaxseed extract pretreatment significantly reduced the micronucleus frequency (P<0.0001). In addition, the results showed the effective role of flaxseed extract as a protective agent in reducing the genotoxicity of the pesticide cyclophosphamide. According to the obtained results, flaxseed is a potent antigenotoxic agent against cyclophosphamide-induced DNA damage. Since the flaxseed extract does not have cytotoxic effects, it can be used as a protective agent against the toxic effects of cyclophosphamide.