فهرست مطالب farnaz hajikarim

Staphylococcus aureus (S. aureus) is one of the major virulence factors of hospital and community acquired infections. Healthcare workers can be the host of S.aureus for many months. And it is very important due to the possibility of transmission to patients. The aim of this study was to determine the prevalence of S.aureus nasal carriers, the antibiotic susceptibility pattern and its effective factors on Sina Hospital workers in Tehran, Iran. healthcare workers from different wards of Sina Hospital were studied in Tehran, Iran in 2010. Samples were taken from both nostrils of each individual. After 18-24hr incubation, the isolates were evaluated by gram stain, catalase, coagulase, DNase and manitol salt agar by which staphylococci were isolated. Disk diffusion antimicrobial susceptibility tests against oxacillin, cefoxitin and vancomycin was performed. Finally, by using PCR, the mecA gene was studied in methicillin-resistant strains (MRSA). 34of the 166 workers, were nasal carriers of S. aureus and one of them was MRSA. The ratio of carriers in operating room workers was more than other wards, without significant relationship (p.value>0.05). S.aureus was found in 34.3% of operating room, 13.8% of nurses and 22.7% of licensed and other personnel. There was a significant relationship between occupations and S.aureus carriage (p.value:0.03). According to the low prevalence of S. aureus and MRSA carriers in Sina hospital, it can be said that the role of the hospital staff as a source of infections caused by S. aureus especially is very low.