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فهرست مطالب hanieh sakha

  • Mirhossein Seyyed-Mohammadzad, Dorsa Kavandi, Mohammad Jalili, Sahar Ghodratizadeh, Amir Mikaeilvand, Hanieh Sakha, Reza Hajizadeh
    Background

    The prevalence and mortality of CVD in women increase over time. We conducted this research to evaluate the severity of coronary artery disease with the number of live births and breastfeeding duration.

    Methods

    Patients aged 30-50 years old with positive exercise tests or evidence of cardiac ischemia who were candidates for coronary angiography were included. All the participants had at least one child. Syntax score was used to evaluate the severity of coronary arteries.

    Results

    Mean number of children was 3.72±1.85, in those patients with <2 live births no one had a syntax score≥1, but in the>5 live births group most patients had a syntax score≥1. In patients with zero syntax score, it was estimated as 4.91±39.7; in patients with 1≤ syntax score, it was 4.48±7.29 (P =0.76). Among patients with > 5 birth lives, those with higher syntax scores had older ages (P=0.497). After adjusting age, the association between live births and syntax score became non-significant (P=0.850).

    Conclusion

    By increasing the number of live births >5, the severity of coronary artery disease, increases. However, this association was not significant after adjusting the age of patients.

    Keywords: Breastfeeding, Livebirths, Syntax Score, Coronary Artery Disease, Pregnancy}
  • Haleh Farzin, Hanieh Sakha *, Reza Eslahi

    In the new modern world, technology has a remarkable role in human life and affects all aspects of it. Indeed, the need for rapid counteractions, especially in medical requirements, can lead to interesting innovations. Telemedicine was disregarded for being an unwieldy, unreliable, and unaffordable technology. Rapidly evolving telecommunications and information technologies have provided a solid foundation for telemedicine as a feasible, dependable, and useful technology. Telemedicine has been conceived as an integrated system of healthcare delivery that employs telecommunications and computer technology as a substitute for faceto- face contact between provider and client. It has the potential for ameliorating seemingly intractable problems in healthcare such as limited access to care among segments in the population, especially the geographically disadvantaged, uneven quality of care, and cost of inflation. Its true merit has yet to be determined by systematic empirical studies. In another survey, the authors defined telemedicine as a branch of e-health, which works by communication networks and delivers healthcare and medical educations from remote locations. The main aim of telemedicine is to overcome the improper distribution of human and fundamental resources. Telemedicine could be considered from the viewpoint of two basic conditions: (1) as an alternative way for emergency services in remote locations and (2) it is a better option rather than conventional health services; for example, teleradiology for rural hospitals. It can result in appropriate availability of health services and acceptable efficiency. However, this aspect of medicine was considered in the late 1990, and then, developing countries have a long way for research about it. 

    Keywords: Technology, Developing Countries, Telemedicine}
  • Reza Imashi, AliAkbar Ghamari, Shaghayegh Dadman, Hanieh Sakha, Jafar Rahimipanahi, Amirhossein Fathi*
    Introduction

     The purpose of this study was to evaluate the effects of positive end expiratory pressure (PEEP) on respiratory parameters and abdominal pain in patients ventilated with a laryngeal mask during cataract surgery.

    Methods

     This clinical trial study included 80 patients in need of cataract surgery (40 in the group without PEEP and 40 in the group with PEEP at 5 cmH2O) who underwent laryngeal mask ventilation during general anesthesia. The parameters of dynamic compliance, pressure peak (Ppeak), tidal volume, SpO2, EtCO2, heart rate, non-invasive blood pressure, and abdominal pain were recorded at intervals of 1, 5, 10, and 20 minutes after the start of anesthesia and were compared between the two groups.

    Results

     Respiratory parameters, heart rate and systolic and diastolic blood pressure were not significantly different between two groups, and only the mean tidal volume at 5, 10, and 20 minutes was significantly higher in the group without PEEP.

    Conclusion

     Application of 5 cmH2O PEEP during ventilation with laryngeal mask in patients undergoing cataract surgery had no significant effect on improving respiratory parameters and pain in the gastric area.

    Keywords: Cataract disease, Laryngeal mask, Positive end pressure, Volume-controlled ventilation}
  • Ahmad Separham, Jamshid Sarnevesht, Hanieh Sakha, Ali Heidari Sarvestani *
    Introduction
    This study aims to compare the clinical outcomes of patients treated with Cre8TM versus Resolute Onyx™ stent.
    Material and Methods
    In this retrospective study, all patients who underwent Stenting in the catheterization department of ShahidMadani Hospital between 2015 and 2018, were included. Angiographic and angioplasty findings were recorded. The primary end point, which includes total mortality, myocardial infarction, revascularization (adverse events) were recorded.
    Results
    The mortality rates were similar in both groups. Moreover the myocardial infarction and repeated revascularization did not differ in both groups (p>0.05).The rates of adverse events wasn't   significantly different between the two groups.
    Conclusion
    Our study showed that efficacy and safety of Cre8™ stents is non-inferior to the Resolute Onyx™ stent.
    Keywords: Coronary Artery Disease, Drug eluting stents, Amphilimus-eluting stent}
  • Ahmad Separham, Mohammad Abbaszadeh, Hanieh Sakha, Ali Heidari Sarvestani *
    Introduction

    Complete thrombotic occlusion of a major epicardial coronary artery is the common pathophysiological mechanism of acute ST-segment elevation myocardial infection (STEMI). Intravascular thrombosis is associated with poor prognosis in patients with STEMI.

    Methods

    In this study, we enrolled 400 patients with STEMI undergoing PPCI . Based on TIMI ratings of the patients and reviewing their angiographic film, they were divided into two groups with high thrombus burden and low thrombus burden. Then, Monocytes were measured in two groups with higher and lower thrombus.

    Results

    A total of 400 patients with STEMI (mean age of 58.71 ± 12.31, 80.5% male) who underwent PPCI enrolled in this study. There were no significant differences between the low thrombus and high thrombus group in In terms of diabetes, high blood pressure, previous history of MI and cardiac troponin levels, However, patients with high thrombus had lower EF .(p value < 0.001). Based on the multivariate analysis result, the amount of circulating monocytes during hospitalization is an independent factor in predicting the rate of thrombosis in angiography. Odds ratio= 3.099 , p value=0.019 .Analysis of the receiver-operating characteristic found an optimal monocyte count cut-off value to be ≤0.60*104 in predicting a high thrombus burden score.

    Conclusions

    The results of the study showed that the number of monocytes is a predicator of high intracoronary thrombus burden in patients with acute STEMI and patients can be treated with antithrombotic treatments.

    Keywords: Myocardial Infarction, Monocytes, Percutaneous Coronary Intervention}
  • Amir Eftekhari Milani, Mohamad Reza Niyousha, Ali Kiavar*, Hanieh Sakha, Ali Mahdavi Fard, Zahra Abdollahi
    Introduction

    Because of increasing the population of premature infants due to improvingneonatal care we try to find other independent criteria in addition to birth weight,gestationalage to reduce the number of infants who need a retinopathy of prematurity (ROP) screeningexamination.

    Methods

    This is a retrospective cross-sectional study,included 150 preterm infants withgestational age of ≤ 32 weeks or birth weight ≤ 1500 g or receives oxygen therapy for more than2 days,who were examined from the fourth week of life for ROP in Tabriz Al-Zahra hospital’sneonatal intensive care unit (NICU),from March 2017 to January 2018. All infants with otherrisk factors such as multi gestational pregnancy,blood transfusion or exchange,phototherapy,underlying disease,cerebral hemorrhage,chronic lung disease,sepsis were excludedfrom the study. Infants divided to two group ROP (n,47),non-ROP (n,133),their5-minute Apgar score was Apgar score was compared as an independent risk factor. Exploratorydata analysis was performed using descriptive measures with independent samples t tests.Kolmogorov-Smirnov tests were used to test the normality of data distribution.

    Results

    The mean 5-minute Apgar scores were statistically lower in ROP group (5.4±2.3) thannon-ROP group 6.2±2.1 (P value,0.041).

    Conclusion

    Apgar score was statistically significant,but in light of the very close resultsobtained,it seems prudent to consider an independent risk factor.

    Keywords: Apgar score, Prematurity, Retinopathy}
  • Reza Hajizadeh, Hanieh Sakha*, Sahar Ghodratizadeh, Ali Soleimany

    Different investigations on seasonal variations of the pulmonary thromboembolism and deep vein thrombosis (DVT) incidence have not yielded a definite conclusion. Some papers showed significant increase in incidence of thromboembolism in winter; on the other hand, others neglected that correlation. Some articles have tried to show infrastructure of these variations. Better understanding of the cornerstone of these variations can result in prevention of disease and saving lives of susceptible people. In this narrative review article, we reviewed previous articles according to the region of study and tried to find the factors affecting diverse results among different studies.

    Keywords: Thromboembolism, Seasonal Variations, Pulmonary Embolism, Deep Vein Thrombosis}
  • مسعود پریش، هاله فرزین، هانیه سخا، ازیتا یحیوی*
    زیاد بوده و بغیر از مخدر ها، داروهای ضد التهابی غیر استروئیدی فراوانی به منظور بیدردی بکار می روند. ولی ترس از عوارض داروئی بویژه اثرات ضد پلاکتی مانع از استفاده روتین و مفید آنها می گردد. هدف از این مطالعه بررسی سمیت داروهای ضد التهابی غیراستروئیدی بر روی پلاکت بیماران تحت جراحی های ارتوپدی بود.
    مواد و روش ها
    در این مطالعه آینده نگر توصیفی مقطعی 370 بیمار در دو گروه 185 نفری مورد مطالعه قرار گرفتند. گروه داروئی شامل بیمارانی بود که تحت درمان با داروهای ضد التهابی غیر استروئیدی بودند و گروه دوم بیمارانی بودند که از دارو استفاده نمی کردند. متغیرهای هماتولوژیک شامل هموگلوبین، هماتوکریت، تست های انعقادی، میزان خون ریزی و پلاکت در دو گروه اندازه گیری و ثبت میشد. تمامی داده های جمع آوری شده توسط تست های آماری مناسب مورد آنالیز قرار گرفته اند.
    نتایج
    در این مطالعه دو گروه از نظر تعداد، سن، جنس، مصرف سیگار، تست های انعقادی و خونریزی حین عمل اختلاف معنی داری نداشتند. مقادیر بیشتر خونریزی حین عمل جراحی از نظر حجم (گروه کنترل) و تعداد (NSAID) مشاهده گردید. در گروهNSAID بیشترین مقدار در مصرف آسپرین دیده شد. شمارش پلاکتی بعداز عمل در بررسی های به عمل آمده در دو گروه NSAID2/6 % وکنترل33/7 %، کاهش پیدا کرد که کم ترین مربوط به کتورولاک وبیشترین مربوط به ناپروکسن بود. کاهش هموگلوبین، هماتوکریت و پلاکت بعداز عمل نسبت به قبل از عمل معنی دار می باشد (005/0˂p)
    نتیجه گیری
    با توجه به نتایج این مطالعه استفاده از داروهای ضد التهابی غیراستروئیدی با دوز کم در بیماران تحت عمل جراحی ارتوپدی اثر سمی روی پلاکت ندارد.
    کلید واژگان: داروهای ضد التهابی غیراستروئیدی, اعمال جراحی ارتوپدی, پلاکت, خونریزی حین عمل}
    Masoud Parish, Haleh Farzin, Hanieh Sakha, Azita Yahyavee *
    Introduction
    Many patients undergo orthopedic surgeries due to trauma. Postoperative pain is high and severe and many nonsteroidal anti-inflammatory drugs are used for analgesia other than opioids. But their use is limited for fear of drug induced complications especially anti platelet effects. The aim of this study was the evaluation of the non-steroidal anti - inflammatory drugs toxicity on platelets function on patients, undergoing orthopedic patients.
    Materials and methods
    370 patients were enrolled in this prospective descriptive cross - sectional study. The study group included 185 patients under treatment with non-Steroidal anti-inflammatory drugs, and the patients with no drug therapy were in control group, hematologic variables including hemoglobin, hematocrit, coagulation test, volume of bleeding and platelets were recorded in tow groups.
    Results
    In this study there was no significant difference between two groups in regard to age, sex, tobacco use, coagulation tests and hemorrhage during surgery. The high volume bleeding (control group) and number (study group) was seen. In study group the most aspirin use was noted. The platelets were decreased postoperatively 6. 2%in study and 7. 33% in control group which the least was related to ketorolac and the maximum to naproxen. The postoperative hemoglobin, hematocrit and Platelet reduction was significant compared to the preoperative value.
    Conclusion
    The results of this study showed that using low-dose non-steroidal anti-inflammatory drug in patients undergoing orthopedic surgeries has no toxic effect on platelets and can be use safely.
    Keywords: Nonsteroidal anti-inflammatory drugs, Toxicity, Orthopedic surgery, Platelets, Intraoperative bleeding}
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