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jafar panahi

  • Jafar Panahi, Mohammad Reza Havasian, Mohammad Ali Roozegar
    Background And Aim
    Teeth are always faced with different traumas and all those traumas, which cause teeth to exit their sockets, are classified as avulsion. Avulsion most commonly occurs in 7-11 year olds. If sports tutors have enough information regarding replantation, they could play a significant role in prognosis of treatment. The purpose of this study was to assess physical education teachers’ level of knowledge regarding avulsion of teeth in Tehran’s Primary Schools, Iran, in 2012.
    Methods
    This was a cross-sectional study which used a questionnaire consisting three parts including 21 questions. The first part was about demographic information; the second part was about traumatic lesion to tooth and the third part was about process of avulsed teeth protection. The questionnaire was completed by a random sample of volunteer sports tutors in Tehran Primary Schools. Collected data were analyzed using the SPSS software using the chi-square test.
    Results
    About 160 subjects participated, 67.1% of the tutors had mid-level knowledge regarding the second part of the questionnaire, and 64.1% had a low level of knowledge regarding the third part. In relation to the second and third part of the questionnaire, a statistically significant relationship was observed between the age of the tutors and their level of information (P < 0.050). There was also a significant relationship between the level of information about the third section of the survey and the amount of experience the tutors had about avulsion (P < 0.050).
    Conclusion
    The results indicate a low level of knowledge in sports tutors in dealing with avulsed teeth and suitable media for transferring the teeth. Suitable educational programs for these tutors could be very useful in enhancing their knowledge and pertaining traumatized teeth.
    Keywords: Dental Trauma, Knowledge, Physical Education Teachers, Iraný
  • محمدرضا هواسیان، جعفر پناهی، نجات مهدیه
    یکی از کشنده ترین اختلالات چند سیستمی و شایع ترین بیماری مغلوب اتوزومی در سفید پوستان است. علت اصلی این بیماری، جهش در ژن پروتئیی به نام Cystic بیماری فیبروزکیستیک (Cystic fibrosis، CF و یا fibrosis transmembrane conductive regulator) CFTR است. جهش های متعددی در ژن CFTR گزارش شده است که منجر به کاهش کارکرد پروتئین CFTR و بروز فنوتیپ بیماری می شود. شایع ترین جهش، (p.F508del (33/33% مرور می شود. تاکنون، در مجموع 56 جهش در بیماران ایرانی گزارش شده است که هشت مورد آن برای اولین بار گزارش شده اند. هفت جهش شایع ایران به ترتیب فراوانی شامل، c.1677delTA (41/7%)،c.2183_2184delAAinsG (56/5%)،p.N1303K (81/4%)،c.2789+5G>A (44/4%)، p.S466X (44/4%) و p.G542X (07/4%) هستند.
    کلید واژگان: فیبروز کیستیک, CFTR, جمعیت ایران
    Mohammad Reza Havasian, Jafar Panahi, Nejat Mahdieh
    Cystic fibrosis is one of the most lethal multi-system disorders and is the most common autosomal recessive disease in Caucasians. The related protein is named cystic fibrosis transmembrane conductive regulator (CFTR). Various mutations in CFTR gene have been reported to cause CFTR loss of function and diseased phenotype. The most prevalent mutation is ΔF508, deletion of phe at position 508. Here, we briefly explain clinical features and diagnostic methods of the disease firstly, and then the genetics of the disease and its mutations as well as genetic studies in Iranian populations are reviewed. Up to now, totally 56 different mutations have been reported in Iranian patients which 8 of them reported for the first time. Seven common mutations in this population are as follows p.F508del (33.33%), c.1677delTA (7.41%), c.2183_2184delAAinsG (5.56%), p.N1303K (4.81%), c.2789+5G>A (4.44%), p.S466X (4.44%) and p.G542X (4.07%).
    Keywords: Cystic fibrosis, CFTR, Iranian population
  • Asghar Ashrafi Hafez, Eghbaleh Asadolahi, Mohamadreza Havasian, Jafar Panahi, Abdollah Davoudian, Mona Lotfikar, Afra Khosravi
    The risk of disease spread through water, fruits and vegetables contaminated through unclean waters varies from region to another. Springs and underground water resources are essentially free of germs or they have tolerable levels of germs; unless they are infected by surface water or human excreta. Scientific reports have shown that outbreaks of food-borne illnesses especially foods such as fresh fruit and vegetables are rising. The aim of the study is to evaluate the effect of washing procedures in eliminating of microbial and parasitic contamination of vegetables consumed in Ilam city. Multiple samples of vegetables were collected from five regions of the city (North- South- West- East- Center) about 1 kg from each shop and transferred to the laboratory. Then we put apiece in a dish containing five liters water; vegetable was washed into it and a sample was collected. Then we added to dish, 20 drops of dish soap and mixed it for a few minutes so that all of vegetable dipped in the foam. After a few minutes, the vegetable were washed with pure water. Another sample was collected from sewage of this water. For detection of microbes, we used two
    Methods
    formalin eater and direct microscopic observation. 86 samples were collected from five regions of city. 40.6% of them had parasitic contamination in scantling water of washing with pure water, and 43% had parasitic contamination in scantling water of washing with dish soap. 70.9% of them had parasitic and bacterial contamination in both wastewaters. There was no significant difference between washing with water and washing with dish soap for parasitic or bacterial contamination. Methods of washing in some types of vegetable may reduce effectively parasitic infection; but we found that washing with dish soap didn’t have any significant effect on reduction of microbial contamination.
    Keywords: Vegetable, Parasitic Contamination, Microbial Contamination, Washing Method, Ilam city
  • محمدرضا هواسیان، جعفر پناهی، ایرج پاکزاد*، عبدالله داودیان، آناهیتا جلیلیان، مونا زمانیان عضدی
    سابقه و هدف

    کاندیدیازیس مهم ترین بیماری قارچی در زنان واژینیت کاندیدایی میباشد. از زمان‌های گذشته تاکنون بطور سنتی از گیاه تشنه داری بصورت وسیع در مناطقی از استان ایلام برای درمان انواع مختلف عفونت ها استفاده شده است، هدف از این مطالعه تعیین اثر مهاری عصاره الکلی و آبی گیاه تشنه داری بر روی کاندیدا آلبیکنس در شرایط آزمایشگاهی میباشد.

    روش بررسی

    تحقیق به روش تجربی انجام گرفت. گیاه تشنه‌داری را پس از جمع آوری در محیطی گرم، خشک و کم رطوبت به دور از نور مستقیم و درسایه خشک شد. تهیه عصاره هیدروالکلی با استفاده از دستگاه عصاره گیری انجام گرفت، تاثیر عصاره به روش دیسک دیفیوژن و انتشار در آگار با تعبیه چاهک غلظتهای 10، 20، 40، 80 و 100 میلی گرم بر میلی لیتر عصاره های هیدروالکلی به مقدار μl20 بر روی هر دیسک استاندارد BLANK DISC و روش انتشار در آگار (تعبیه چاهک) در غلظت‌های 10 ، 20 ، 40 و 80 میلی گرم بر میلی لیتر عصاره هیدروالکلی به مقدار μl 30در هر چاهک 3 بار مورد آزمایش قرار گرفت.

    یافته‌ها

    نتایج قرایت شده در زمان های24 و 48 ساعت پس از کشت در دمای37 درجه سانتی گراد حاکی از بی اثر بودن عصاره الکلی و اثر ضعیف عصاره آبی بر روی کاندیدا بود.

    نتیجه‌گیری

    با مشاهده بی تاثیری عصاره الکلی این گیاه میتوان گفت که عصاره الکلی حاوی ترکیبات ضد قارچی نمی باشد. اما عصاره آبی این گیاه در بالاترین غلظت دارای اثر مهاری ضعیفی بوده که ناشی از وجود ترکیبات موثر در گیاه مبی باشد. پیشنهاد می شود از عصاره فنولی این گیاه در مطالعات دیگر استفاده شود. 

    کلید واژگان: عصاره هیدروالکلی, تشنه داری(Scrophularia striata), کاندیدا آلبیکنس
    Moammad Reza Havasian, Jafar Panahi, Iraj Pakzad*, Abdollah Davoudian, Anahita Jalilian, Mona Zamanian Azodi
    Background

    Candidiasis is one of the most common opportunistic fungal diseases in humans, candida vaginitis being the most important fungal disease in women. Traditionally, different plant extracts are used in Western Iran for treatment of vaginal infections. This study aims to evaluate the inhibitory effects of aqueous and alcoholic extracts of Scrophularia striata on Candida albicans isolated from patients with vaginitis.

    Materials and methods

    Scrophularia striata plants collected from the Zagross Mountains were dried in shade. Aqueous and alcoholic extracts of Scrophularia striata were prepared by rotary evaluation. Inhibitory effect of extracts was studied by disk diffusion and embedding sink diffusion.

    Results

    This experiment indicated that no concentration of the alcoholic extract of Scrophularia striata had an inhibitory effect on candida albicans but the aqueous extract in maximum concentrations of 100 mg/ml had some inhibitory effect on this fungus.

    Conclusion

    Since people in Western Iran use this plant for treatment of infections, we expected these extracts to have significant inhibitory effect on candida albicans but the result was contrary to our expectations. Keywords: Scrophularia striata, Aqueous extracts, Alcoholic extract, Inhibitory effect, Candida albicans.

    Keywords: Scrophularia striata, Aqueous extracts, Alcoholic extract, Inhibitory effect, Candida albicans
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