jamshid kabiri

The aim of this study was to compare the effects of Two drug combinations of Torsemide-Enalapril-Digoxin and Furosemide-Enalapril-Digoxin on the cardiovascular system in the treated dogs. For this purpose, five 1.5-year-old mixed breed dogs were selected to undergo echocardiography at three times (The first time as the control group, the second time as the first group and the third time as the second group). No drugs were used in the control group. In the first group, 2.5 mg/kg of furosemide, 0.5 mg/kg of enalapril and 3 µg/kg of digoxin and in the second group, 0.3 mg/kg of Torsemide, 0.5 mg/kg of enalapril and 3 µg/kg of digoxin were administered orally. Echocardiography of the dogs was done after one hour of drug administration. Measured echocardiographic parameters included: Left ventricular size during systole, left ventricular size during diastole, heart rate and fractional shortening. The results of each group were evaluated using chi square analysis method. The results of this study showed that changes in heart rate and left the ventricular size changes during diastole were not significant between the control and other groups. Although left ventricular size during systole was significantly lower in the torsemide-enalapril-digoxin group than the other groups, in this study, it was found that the fractional shortening changes in the group receiving torsemide-enalapril-digoxin were significantly higher than the other two groups. The results of this study indicate better effects of torsemide than furosemide in improving heart function and increasing short fractional shortening, but both drugs have similar effects on other cardiac parameters.

A Kurdish 6 year-stallion referred to the Veterinary Clinic of ShahreKord University with complaint of enormous skin and subcutaneous tissue injuries and ulcer in dorsal and palmar side of both metacarpal regions. Based on the patient's history, walking of the stallion on the tarmac path immediately after shoeing caused severe swelling of metacarpal region and traditional remedy were performed by dressing crashed fresh garlic on the affected area for 3 days. Clinical examination and radiographic evaluation showed vast skin and subcutaneous wound and injury, tissue necrosis, massive granulation tissue formation and metacarpal bone involvement. In laboratory investigation of hemogram, severe leukocytosis along with mild left shift, toxic neutrophil and fibrinogen increase were observed. Wound management consisting of second intension of wound healing like as debridement of granulated and necrotic tissue and lastly, dressing the ulcers with local silver sulfadiazine, NSAID prescription and stall resting were ordered. Spite of many advantageous of fresh garlic as an herbal treatment, there were rarely documents of skin burn due to local application of raw garlic in human and the present study would be counted as the first report in horse after traditional remedy.