فهرست مطالب k. zare

In this work, we consider the joint distribution function as well as the copula of $(X+Z,Y)$ where the random vector $(X, Y, Z)$  is characterized by a copula $C_{X,Y,Z}$. We use this copula to analyze a Berkson measurement error model. By presenting a general form of a Berkson measurement error model with copula-dependent random variables, we investigate some of its special cases. Some theoretical results, several examples as well as a simulation study, are proposed for illustration.

It is well known that bias in parameter estimates arises when there are measurement errors in the covariates of regression models. One solution for decreasing such biases is the use of prior information concerning the measurement error, which is often called replication data. In this paper, we present a ridge estimator in replicated measurement error (RMER) to overcome the multicollinearity problem in such models. The performance of RMER against some other estimators is investigated. Large sample properties of our estimator are derived and compared with other estimators using a simulation study as well as a real data set.

This paper proposes a new method to allocate the transmission fixed costs among the network participants in a pool based electricity market. The allocation process relies on the circuit laws, utilizes the modified impedance matrix, and is performed in two individual steps for generators and loads. First: to identify the generators contributions into the usage of the transmission facilities, the generators are modelled as current injections and the loads as equivalent impedances. Second: to identify the load's contributions into the usage of the transmission facilities, the loads are modelled as current injections and the generators as impedances. To split the mutual terms between the involved components, the equal sharing principle is used and proved to be rational by the Shapley and Aumann-Shapley values as two preferred game-theoretic solutions. The proposed approach is also applied to determine the generators contributions into the loads, thus, a new concept, named, circuit-theory based equivalent bilateral exchange, is introduced. Numerical results are reported and discussed to validate the proposed cost allocation method.

Diminishing protein aggregation by chaperone is very important factor in medicine and industry. In this paper, itis induced the chaperone ability for 0-casein upon modification of its acidic residues by Woodward reagentK(WRK) and examined on lysozyme as a target protein at pH 7.2 and outlined the mechanism for chaperoneability of modified system by UV-Vis and fluorescence spectroscopy and theoretical calculation methods.

Nowadays apphcanon of nanotubes in biology and medicinal science is more investigated. Nanotubes can passthroueh cell walls and transport and release drugs in special tissues. The purpose of this paper is to investigatethe interaction of a nanotube having hydroxyl functional groups (OH) with an anticancer agent. In this worktransporting of an anticancer drug named 2-(2-amino 6,7-dimethyl Pteridine 4-ylammo)-ethanol by a zigzagnanotube with 60 C atoms (5,0) is investigated. The methods used are quantum mechanics and seroiemphical.Two composites of the drug and nanotube are under studying: I-compose of drug and nanotubes wall 2-compose of drug and one of the two heads of nanombe. At first some hydroxylic functional groups are put onthe head of nanotube and then an etheric bond formed between agents. The results show that the composite ismore stable than the single agent. Also binding of drug with the head of the nanotube is more stable than thewall. In the other case the Interaction between a carbon nanotube (9,0) and Levothyroxine as a drug isinvestigated. All of above composites art investigated by semiempincal methods and MolecularMechanicsiMolecular Ilymunics simulation in body temperature (310 K) and their heat capacities are obtainedin water, methanol and ethanol solutions separately. The results show that by increasing initial temperature inmost of the cases heat capacity increase& Also it can be seen that by increasing of solvent molecular mass, theheat capacity increases too.

Plane-wave pseudopotential Density Functional Theory (OFT) periodic slab calculations were performed usingthe giteralized gradient approximation (GHA) to investigate the adsorption of nitric oxide(NO) on the (I II)surface of Cu. Copper rface was stimulated using th P 'odic Slab Method consisting of Five atomic Layers.Four different adsorption saes (Atop. Bridge, RCP Hollow, and FCC Hollow) were considered. Resultsspecified that the suitable site for NO adsorption in molecular foun is the Hollow FCC site, and molecularadsorption is more stable than dissociative adsorpnon energetically.

The binding data for interaction of a homologous series of n-alkyl sulfates with alkyl chainlengths from C8 to C12 with insulin were analyzed on basis of Hill equation for two classes ofbinding sites .The intrinsic Gibbs free energies were calculated and resolute on basis ofelectrostatic and hydrophobic contributions The estimation of these contributions reveals themajor role of electrostatic interactions on first binding set and the minor one in the second.