khaterh anbari

Coxiella burnetii is the cause of Q fever. There is no adequate information about Q fever in rural pregnant women in Iran.

The aim of this study was to investigate the seroprevalence of C. burnetii infection among rural pregnant women with historical contact with livestock in Khorramabad (western Iran).

This cross-sectional was conducted from December 2016 to June 2017 on 184 samples collected randomly from rural pregnant women who referred to clinical laboratories and health centers in Khorramabad. The data were examined using indirect ELISA assay kits for the detection of C. burnetii phase II human antibodies in their serum samples.

Of 184 serum samples of rural pregnant women, 89 (48.4%) were positive, 76 (41.3%) negative, and 19 (10.3%) suspected. In addition, there was a significant relationship between age, pregnancy, abortion, and the location of the village relative to the city. The results suggested that more positive samples were observed in women that lived in the eastern villages of Khorramabad city; however, the difference was not statistically significant (P value = 0.535).

The present study demonstrated the high seroprevalence of C. burnetii in rural pregnant women, which necessitates preventing the unwanted side effects of the disease. Rural pregnant women should pay more attention to the disease and its dangerous effects.

Although intravenous injection is nowadays one of the common invasive procedures in medical care، but like any other procedure، it has a lot of side effects. Phlebitis is the most common complication and one of the therapeutic aims is to prevent it.

The aim of this study was to compair the effect of Clobetasol with Nitroglycerin ointment on the prevention of superficial IV Catheter induced phlebitis.

This clinical trial study was conducted on 144 patients admitted in men surgery ward in Arak Valiasr hospital in 1392. Patients were randomly allocated into three groups: Group A (Clobetasol)، Group B (NTG) and Group C (Control). Severity of phlebitis was measured using the standard visual rating scale. In intervention groups، after venipuncture، ointment were administered on the distal portion of IVcatheter and the area was dressed. The venipuncture area was assessed 24، 48 and 72 (hrs) after venipuncture. Data were analyzed by chi-square، Fisher''s exact and Kruskal-Wallis statistical tests and using spss19.

There was no significant difference among three groups in terms of severity of catheter induced phlebitis in the first and second measurements. In the third measurement there was a significant difference among intervention and control groups (P < 0/007) and the severity of catheter induced phlebitis was reduced more in NTG group comparing Clobetasol group.

The use of Nitroglycerin in prevention of superficial، IVcatheter induced phlebitis is more effective than Clobetasol. It is suggested that Nitroglycerin can be administered to prevent phlebitis in patients who need to have IVcatheter for a long time (over 48 hours).