فهرست مطالب leila mousavi seresh

Ovarian superovulation and increased follicle-stimulating hormone concentration for infertility treatment may be the risk factors of developed granulosa-cell tumor. The aim of this report is to introduce a case of granulosa-cell tumor which was discovered after ovarian stimulation.

A 31-yr-old woman with clinical presentation of massive abdominal distention was referred to the gynecology and oncology department of an academic hospital, Mashhad University of Medical Sciences in Aug 2017. She had the history of secondary infertility and was undergoing In Vitro Fertilization protocol and ovarian stimulation, but, the cycle was canceled. The patient suffered from gradual abdominal distention one month after the end of IVF procedure despite pregnancy failure. 2-3 months after management of the ovarian hyperstimulation syndrome, investigation revealed large ovarian mass and increased tumor marker inhibin. Exploratory laparotomy was performed and revealed stage III ovarian cancer. The final pathology report indicated juvenile granulosa cell tumor. So, optimal surgical staging and cytoreductive surgery without fertility preserving were perfumed. Chemotherapy was recommended due to the advanced stage of ovarian cancer. Unfortunately, she experienced metastatic diseases in pelvic and abdomen in less than six months; and currently is receiving the second and third line chemotherapy.

Persistent ovarian enlargement or ascites during or after infertility treatment should be carefully considered and managed.

Isolated metastasis of cervical carcinoma to iliopsoas region might be infrequent and its occurrence is a diagnostic challenge. The aim of this study was to report a case of iliopsoas muscle metastasis from cervical carcinoma.
A 52-year-old multiparous females complaining about post menopause bleeding was referred to the researcher’s oncology department. Gynecological examination revealed cervical mass with involved parameters and biopsy confirming squamous cell carcinoma. In addition, the patient had a large cystic mass on the lateral side of pelvic area and abdomen. Investigations detected solid ovarian mass associated with a rise of tumor marker CA-125 and CEA levels. Magnetic resonance imaging (MRI) and CT scan reports suggested possible hematoma in iliopsoas muscle. Imaging-guided biopsy detected metastatic squamous cell carcinoma in iliopsoas muscle mass. Based on diagnosis of advance stage cervical cancer, the patient received chemotherapy following adjuvant radiation therapy.
Metastasis of squamous cell carcinoma of the cervix to iliopsoas muscle is considered as a rare event. It is recommended to keep this unusual manifestation in mind.

Choriocarcinoma is one of the rare diseases of gestational trophoblastic tumor with various and sometimes misleading clinical presentations. Clinical suggestion of the disease and timely diagnosis can be useful. The aim of this study is to report a case of diagnostic medical error in postpartum choriocarcinoma.
Case report: A 25-year-old woman with prolonged postpartum hemorrhage referred to the hospital in one of the cities around Mashhad. Despite frequent referring of the patient due to bleeding, and not considering laboratory signs and sonography and increased levels of βhCG, gestational trophoblastic tumor was not diagnosed. It led to uterus rupture. Then, with emergency situation due to uterus rupture, multiple lung and brain metastases, she was referred to the gynecologic oncology ward in 2017. Currently, she is under chemotherapy without need to surgery.
The possibility of choriocarcinoma should be considered in every woman of reproductive age with postpartum abnormal uterine bleeding and also bleeding from other organs or diagnosis of metastasis with unknown etiology.

Severe vaginal bleeding after postpartum is an emergency in obstetrics and if not treated appropriately associated with high mortality. Uterine artery embolization is a minimally invasive procedure and effective method in addition to control bleeding, moreover may also preserve fertility. However, this method is also associated with complications such as ischemia and uterine rupture. The aim of this article is to report of a case of necrosis and rupture of the uterus following uterine artery embolization.
Case report: A 23-year-old woman with clinical presentation of massive postpartum hemorrhage was referred. She had history of twice Cesarean section and suffered severe vaginal bleeding after last surgery. Uterine artery embolization was performed and following it, because of repeated and uncontrolled vaginal bleeding, inevitably explorative laparotomy was performed. During surgery due to rupture of the myometrium and the impossibility of its restoration, she underwent hysterectomy. Pathology report confirmed the diagnosis.
Despite the effective beneficial outcomes of uterine artery embolization, due to its complications, proper indication and careful attention should be considered.