فهرست مطالب mahdi arjipour

Chronic low back pain (CLBP) is a leading cause of absenteeism and increased reliance on health insurance and healthcare services, impacting individuals' daily lives and overall quality of life. This study aimed to examine the impacts of aquatic open and closed kinetic chain exercises on psychological factors, pain, and lumbo-pelvic stability in men with non-specific CLBP.

In a randomized controlled clinical trial, 60 men with non-specific CLBP (diagnosed by a specialist) were randomly assigned to three groups: closed chain exercises in water, open chain exercises in water, and a control group. The intervention groups followed a prescribed exercise regimen for eight weeks, with three sessions per week in the pool. Pain was assessed using the Visual Analogue Scale (VAS), lumbo-pelvic stability was measured with the Pressure Biofeedback Stability device, and psychological variables were evaluated using the Depression Anxiety and Stress Scale (DASS-21). The ANCOVA test was used to compare post-test values among groups while controlling for pre-test effects.

Significant differences were observed between the control group and both the open chain and closed chain exercise groups in terms of pain, lumbo-pelvic stability, and psychological variables (p<0.05).

The implementation of open and closed chain exercise programs in aquatic environments proved effective in reducing pain among individuals with CLBP, also showing potential for improving lumbo-pelvic stability and psychological well-being. Hydrotherapy programs, as part of comprehensive rehabilitation strategies, may be beneficial for patients with CLBP.

Patients who undergo spine surgeries need self-care to reduce complications and overcome post-operative anxiety. One of the new methods of post-operative care training is educational software design technology. This study aimed to determine the effect of post-spinal surgery care education with motion pictures designed based on the health belief model on patients' anxiety and health belief.

This study was quasi-experimental, with a post-test design conducted in Hamadan from 2021 to 2022. The statistical population included all patients undergoing spine surgery (except for the cervical area). A total of 122 patients were selected using convenience sampling and then randomly assigned to either the control or experimental group. The experimental group received post-operative care training through motion pictures designed based on the health belief model installed on their smartphones. The data was collected two months after the intervention using the Spielberger Anxiety Questionnaire and a Researcher-Made Questionnaire to measure the constructs of the Health Belief Model, which were confirmed to be valid and reliable. Data analysis was done using SPSS software ver.25. A significance level of p<0.05 was used in this study.

The mean health belief scores in the experimental group were significantly higher than those in the control group (P < 0.05). However, there was no significant difference in the mean anxiety scores between the two groups after the intervention (P = 0.958).

Teaching post-operative care to patients using new methods, such as motion pictures, can have a positive effect on increasing the patients' belief in their health after surgery. This can impact the results of surgery and the recovery of patients. Due to the lack of significant changes in anxiety scores after the intervention, further studies are necessary to explore methods for reducing patient anxiety following spinal surgeries.

Pre-operative glial brain tumor grading could determine the management. Perfusion weighted magnetic resonance imaging (PWMRI) is a promising modality for assessment and management of brain lesions.
In this study, we assessed the diagnostic efficacy of this method in the grading of supratentorial gliomas using 3 Tesla MRI.
Patients and Using a 3 Tesla MRI unit, 35 (20 male, and 15 female) patients with glioma were examined one month before surgery. Imaging protocol was: 615 slices, field of view (FOV) 22 × 22 cm2 T1W spin echo: repetition time (TR) 500 -echo time (TE) 30 and (FOV) 22 × 22 cm2 T2W Turbo spin echo: TR 5000 -TE 90. Then 15 cc gadolinium was injected at the rate of 3cc/s and imaging was repeated with: TR: 2360 TE: 45, flip angle 90, band width 1346 echo planar imaging (EPI) 128 measurement 50. Mean transit time (MTT), cerebral blood flow (CBF) and cerebral blood volume (CBV) were measured at enhancing and edematous regions compared to contralateral white matter. Then, an appropriate biopsy was performed from different sites of the tumor during surgical excision. Standard hispathological examination that was assessed in a double-blinded manner, was considered as gold standard.
Patients’ tumor distribution was grade IV in 14 (40%), grade II in 14 (40%), grade III in six (17.1%) and grade I in one (2.9%). Relative CBF (rCBF), and rCBV was significantly more in high-grade glioma (HGG) versus low-grade glioma (LGG) (P PWMRI is more accurate than conventional MRI for noninvasive discrimination of low-grade glioma (LGG) and high-grade glioma (HGG) that could be helpful for neurosurgeons in decision making dealing with the most common tumor of the brain.

Sildenafil (Viagra) has been introduced to treat erectile dysfunction by acting as phosphodiesterase 5 inhibitor and hence accumulation of guanosine cyclic monophosphate (cGMP). On the other hands, the nitric oxide/cGMP signaling pathway has crucial role in synaptic plasticity processes like long-term potentiation (LTP) in the central nervous system considered as a model of learning and memory. The aim of the present study was to determine the effects of sildenafil on different stages of spatial learning and memory of rat using radial maze. The effects of pre-training, pre-retrieval oral administration or post-training i.p. injection of sildenafil (10 mg/kg) in radial maze task were investigated. Pre-training and post-training administration of sildenafil impaired radial maze task. Pre-retrieval injection of sildenafil decreased reference memory and working memory errors. Therefore, sildenafil impaired acquisition and consolidation of spatial learning and memory but improved retrieval of spatial memory in radial maze. Sildenafil has differential effects on the spatial learning and memory processing. It seems this result is due to accumulation of cGMP in the neural structures related to learning and memory processing. As different neural structures are involved in different learning and memory tasks, these results might be due to the different actions of cGMP in different structures of brain.