فهرست مطالب majid halimi khalilabad

In this research, the volatile compounds of Oleo gum resin of   Ferula gummosa were extracted from the protected area of Saluk located in North Khorasan province of Iran by water distillation method and the chemical compounds were identified by GC-MS and reported for the first time. In the studied plant essential oil, 42 compounds that made up 95.78% of essential oils have been identified, the main components of which are β-pinene (44.51%), α-pinene (11.49%), para-cymene (2.48%), 3-carene (5.74%), and 2-isopropyl 4-methylanisole (4.58%). In the following, five identified main compounds of this plant were compared with the main compounds of 26 ecotypes that were previously reported. By comparing the five main compounds of these 27 ecotypes, it was found that the main compounds of these samples are classified in the category of monoterpenes, sesquiterpenes, and esters, and also by drawing a cluster dendrogram using R software, the proximity and distance of these samples in terms of the type of main compounds, it is clustered into three clusters including samples with similar compounds. This study can be effective in continuing the research on eco-phytochemistry and ethnobotanical characteristics of Frula gummosa.

The study of alkaloids from methanolic extract of Crucianella sintenisii from Rubiaceae family has not been studied yet. In this research, the methanolic extract was initially prepared from the aerial parts of Crucianella sintenisii, and then the resulting extract was acidified by acetic acid to remove neutral compounds. The neutral compounds were extracted by EtOAc (ethyl acetate). The resulting extract was alkalized with NH3 (25%), and then extracted with chloroform solvent. Finally, the crude alkaloid is extracted and ready to be injected into the MPLC device. One fraction was isolated, and the structure of 2-methyl-3-phenyl indole from the category of indole alkaloids was confirmed by using the spectroscopic techniques (NMR, ESI-MS, and IR). The therapeutic activities of the plant indole alkaloids are extensive, and most of these activities are related to the indole core in these structures.

The aim of this study is to determine the chemical composition of essential oils of Chaerophyllum ‎khorassanicum belonging to the Apiaceae family for the first time. Identification of essential oils ‎is necessary, for food, cosmetics- health industry, and medicinal uses. The plant was collected at ‎the flowering stage of Khorassan Razavi Province in Iran, Farizi Village. The shoot parts of the ‎specimen were dried in the laboratory and crushed to particles. The essential oils were obtained ‎by hydro-distillation using Clevenger and analyzed by GC-MS. Fifty-one components were ‎identified in Chaerophyllum khorassanicum essential oils which accounted for 97.2% of the ‎essence. The major chemical category of the volatile compounds were the monoterpene ‎hydrocarbons (65.5%), followed by oxygenated monoterpenes (24.5%). In particular, the main ‎components were limonene 32.1%, methyl eugenol 16.2%, and β-Ocimene 15.6%. In conclusion, ‎monoterpene hydrocarbons are characteristic and represent excellent chemotaxonomical markers ‎for Chaerophyllum khorassanicum.