marmar firouzpour

Tubal factor is a very Common cause of infertility. This study was performed to assess the therapeutic effect of Intrauterine Insemination (IUI) in patients with unilateral fallopian tube obstruction and to reduce indications of IVF and ICSI. This case-control study was performed between years 2008-2009 in Fatemeh-Zahra infertility center of Babol on 60 patients with unilateral tube occlusion (case group) and one 120 infertile patients without tubal obstruction (control group) in HSG. Subjects were selected by sampling method. Demographic data were collected by a researcher-made questionnaire and analyzed by SPSS Software (version 16) using descriptive statistical methods and t-test and Chi-square test. Pregnancy was achieved in 4 patients (6.7%) of case group and 15 patients (12.5%) in control group but the difference was not significant (P>0.05). All 4 pregnancy cases had left ovarian tube obstruction and none of patients with right ovarian tube obstruction became pregnant, but the difference was not significant (P>0.05). Pregnancy rate had no significant difference base on site (distal or proximal) of involvement (p=0.99). Pregnancy rate after IUI has no significant difference in patients with unilateral tube obstruction and infertile women with patent ovarian tubes. Therefore, IUI can be suggested to patients with unilateral ovarian tube obstruction regardless of involvement site.