maryam tajik

Myocardial perfusion imaging (MPI) is a noninvasive method with acceptable sensitivity and specificity in diagnosing coronary artery disease (CAD) in moderate-risk patients, including those with CAD risk factors.

The present cross-sectional, prospective study was conducted on 4886 patients from April 2020 through March 2023 at Chamran and Tehran Heart Center hospitals. A questionnaire regarding anthropometric variables, demographic characteristics, CAD risk factors, and MPI findings was designed.

Totally, 2179 patients (44.6%) had abnormal MPI. Patients with abnormal MPI were significantly older than those with normal MPI. Older age (OR, 1.64; 95% CI, 1.2 to 1.72; P<0.001), diabetes mellitus (DM) (OR, 1.36; 95% CI, 1.1 to 1.48; P=0.012), hypertension (OR, 1.24; 95% CI, 1.04 to 1.37; P=0.032), and dyslipidemia (OR, 1.54; 95% CI, 1.25 to 1.8; P<0.001) were associated with abnormal MPI independently. Patients with more CAD risk factors were more likely to have abnormal MPI. Thus, in patients without or at most with 1 risk factor and those with 8 CAD risk factors, the likelihood of abnormal MPI was 3.7% and 76.2%, respectively. The frequency of left ventricular dilation and right ventricular prominence was significantly higher in patients with older age (P<0.001 and P=0.043, respectively), dyslipidemia (P<0.001 and P=0.007, respectively), DM (P<0.001 and P<0.001, respectively), and hypertension (P=0.048 and P=0.057, respectively).

Individuals with CAD risk factors, especially those with older age, DM, hypertension, or dyslipidemia, require meticulous attention during CAD evaluation, particularly via MPI.

Problem statement: 

Museums are among the most valuable places in the world. Tehran has rich historical, cultural, scientific, entertainment and tourism museums. Determining the visual identity strategy of museums is the responsibility of graphic designers. Using communication and advertising tools, the graphic design of museums is done by displaying visual information in the forms of visual identity design and environmental graphic design. The research in this field has mostly focused on the area of museum marketing and the study of environmental graphics. Studying the brand strategy in the visual identity of museums, this research analyzed the data gathered from several samples of the study in Tehran and around the world.

is to study those samples qualitatively and help develop strategic solutions in graphic design for cultural and touristic places such as museums in Tehran. The current research attempted to answer the following questions: What are the characteristics of the visual identity in Tehran museums from the graphic design perspective? And what strategies have Tehran museums applied for their visual identity?

This study used library and documentary sources and employed the descriptive-analytical method to comparatively study the examples of visual identity in Tehran museums.

In designing its visual identity, Tehran museums have used the following strategies: using the main brand name, using the image of the museum building, using typography in the design of the museum logo, distinguishing and adhering to the principles of service design, the national approach, and being inspired by tradition. Also, from the graphic design point of view, Tehran museums have followed the logo guide rules and have used unique typefaces and briefcases for the visual identity of their brand.
This research shows the importance of formulating, planning, and implementing a comprehensive strategy toward the integration of visual identity design in Tehran museums.

Wound healing is a critical clinical concept. We aimed to evaluate the effects of topical Mentha piperita essence on cutaneous wound healing.

This randomized controlled trial was conducted in Tehran University of Medical Sciences, Tehran, Iran in 2019. Square-shaped 1.5×1.5 cm wounds were made on the neck of 60 male Wistar rats in a sterile condition. Samples were randomly divided into a control group and three experimental groups. Group A treated with M. piperita essence and Vaseline. The second group received the M. piperita essence, and the third group received Vaseline. Histological specimens were obtained in 4th, 7th, and 14th days and were explored for fibroblasts, epithelial cells, inflammatory cells, and vessels. RT-PCR was performed for molecular and gene expression evaluation of TGF-β.

The M. piperita essence increases TGF-β gene expression as an important factor in wound healing. After 14 d, group A, who received M. piperita and Vaseline, had 99.73% of wound healing with the mean wound size of 0.006 cm2 while wound healing in the control group was only 52%. Samples treated with M. piperita have 74.58% wound healing following by group treated with Vaseline, which was 67.02% (P<0.05), respectively.

The application of the M. piperita essence for wound healing accelerates the process and improves outcomes.

Different factors can affect the future of a person with cancer. Patient’s systemic inflammatory response is an important factor. Several inflammatory markers have been evaluated for measuring the patient’s response to cancer. In this retrospective cohort study, we evaluated neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) as prognostic factors of surveillance in patients with pathologic approved esophageal cancer.

In this retrospective cohort study, patients with pathologically approved esophageal cancer, who underwent surgical treatment in cancer institute of Iran, were included. Demographic, pathologic and laboratory data of patients were obtained from archive of medical records.

In this study 135 patients with esophageal cancer with mean age of 60 years were studied.The median time of follow-up period was 21 months. Mean NLR and PLR were 7.05 and 898 respectively. Patients’ survival had a significant relationship with patients’ age, gender, tumor’s diffrentiation, receiving chemotherapy, absolute neutrophil count, total bilirubin, direct bilirubin, and NLR.

According to the results, in a multi variable investigation, it was demonstrated that a high NLR has a direct effect on patients’ poor survival.

In Iran, cancer is the third leading cause of death. Obtaining basic data about knowledge of general population regarding cancer is necessary to program a proper primary cancer prevention plan. The previously collected data in Iran about cancer knowledge was not based on a comprehensive, standard questionnaire. Therefore, the aim of this study was to prepare an appropriate questionnaire to fill this gap.
The Awareness and Beliefs about Cancer (ABC) questionnaire was chosen as the ideal tool for data collection. The questionnaire was translated, back translated and modified based on the comments of experts. The clarity and appropriateness of the translated version of ABC was tested by interviewing a select population of 30 Iranian individuals.
We developed a Farsi version of the ABC questionnaire containing 47 main questions corresponding to the original ABC. Slight modification and additions were applied.
The Farsi version of the ABC questionnaire is an appropriate tool for the evaluation of the knowledge, attitude, and behavior of the Iranian population regarding cancer prevention.

New treatment and vaccination strategies provide the opportunity for eliminating viral hepatitis. Lack of adequate knowledge seems to be a barrier against hepatitis elimination due to the emergence of newly infected cases.
The aim of this study was to evaluate the knowledge of Iranian (bio)medical students regarding hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and to determine the effect of hepatitis public awareness campaign (PAC), held by the students, on their knowledge level.
This prospective study was conducted during PAC by Iran Hepatitis Network for World Hepatitis Day in 2016. The PAC had 2 major parts: 1) training of the registered (bio)medical students in a workshop; and 2) sending the trained students to Tehran metro stations to promote public hepatitis awareness on July 26 - 28, 2016. Hepatitis knowledge of the students was evaluated by a validated questionnaire before the workshop, after the workshop, and after the end of PAC.
A total of 91 undergraduate students participated in the workshop, PAC, and the survey. The mean total knowledge scores of the students before and after the workshop were 56.2 ± 18.0 and 75.8 ± 17.9, respectively. Moreover, the scores further increased to 96.6 ± 6.1 after the end of the campaign (P The results demonstrated that knowledge regarding HBV and HCV infections is not sufficient in the study population. Therefore, we suggest using social activities and awareness campaigns to increase awareness among (bio)medical students.

Bone metastases are the most common cause of cancer-related pain in various primary malignant tumors, most often, breast and prostate. 188Re-hydroxyethylidene diphosphonate (188Re-HEDP) is a new and less expensive bone seeking radiopharmaceutical with favorable physical characteristics of the radionuclide such as short half life of 16.9h, maximal β energy of 2.1 MeV with a 15% γ-component of 155 keV and easily available from an in-house 188W/188Re generator. The aim of this study is to evaluate the therapeutic efficacy and safety profile of bone palliative therapy following administration of 188Re-HEDP. Twenty patients with painful metastatic bone lesions secondary to breast, prostate, multiple myeloma, ampulla of vater and lung cancers received 1 mCi/kg of 188Re-HEDP. Four hours after treatment, post-therapy scintigraphy was performed. All patients were interviewed using a standard set of questions (visual analogue scale: VAS) concerning their pain relief before, and after therapy at weekly intervals for the first month and every 2 weeks for the following 4 months. The general condition of the patients was also evaluated by Karnofsky-index and ECOG (Eastern Cooperative Oncology Group) performance status. Hematologic profiles were recorded before treatment and every two weeks up to 8 weeks after treatment. Overall pain relief was found in 68.8% of patients. Decreased from 8.37±2.12 to 5.68±2.98 at VAS was observed 4 weeks after treatment. The osteoblastic lesions (breast and prostate) showed rather similar response to the treatment. Mean platelet counts decreased in 6th week and returned to baseline level in 8th week. One patient showed grade III leukopenia without any serious complication. 188Re-HEDP is an effective radiopharmaceutical for metastatic bone pain palliation therapy. Side effects include mild and transient thrombocytopenia and leucopenia and no life threatening side effect is observed.

Many extra-intestinal manifestations are associated with celiac disease. One of the most important of them is hepatobiliary abnormalities. This association is recently under consideration. We report a 34-year-old man with elevated liver enzymes and primary diagnosis of nonalcoholic fatty liver disease. Further follow up revealed celiac disease as the proper diagnosis in this patient.

The Inflammatory bowel diseases (IBD) have been found to accompany some neurological syndromes including multiple sclerosis (MS). Recently, Several studies have reported and discussed the simultaneous presence of IBD and MS in some patients. Thus, in patients with either disease, the presence of signs and symptoms of the other should raise the clinical suspicion of the clinician and warrant special considerations. In this report, we introduce two IBD patients who have concomitant involvement of MS.