فهرست مطالب massoud movahedi

Today, information technology has had many benefits in accelerating and facilitating maintenance activities, creating a branch called E-maintenance. Implementation of a E-maintenance system for defense organizations that have problems with the military equipment maintenance, has a major impact on their success or failure on missions and can facilitate and improve the effectiveness of the maintenance. To go beyond traditional maintenance approaches, and to create an e-maintenane framework, one needs to evaluate the state of e-maintenane maturity, to identify its current position in e-maintenance maturity, and to plan for the full maturity of electronic net. Due to the lack of a maturity evaluation model for the e-maintenane system, the aim in this research is to present a maturity evaluation model of the e-maintenance system for defense organizations. By examining the literature of the subject, and related maturity models, and preparing a questionnaire for people's opinions, expert in the field of maintenane, the maturity model was presented in 6 dimensions and 67 indices, and maturity levels were based on CMMI. Finally, on the basis of a checklist extracted from the defined maturity indices and levels, the maturity of a defense organization's e-maintenance system was evaluated.

Chronic granulomatous disease (CGD)، a rare inherited primary immunodeficiency disorder، is caused by mutation in any one of the genes encoding components of nicotinamide adenine dinucleotide phosphate (NADPH) -oxidase enzyme. NCF2 gene (encoding P67-phox component) is one of them and its mutation is less common to cause CGD (around 5-6%). Here، we assessed mutation analysis of NCF2 in 4 CGD patients with p67-phox defect in Iran. These patients showed classical CGD symptoms. NCF2 sequence analyses revealed two different homozygous mutations including a nonsense mutation in exon 4، c. 304C>T (Arg 102X) in one case and a CA deletion in exon 13 (Leu346fsX380) in one brother and sister; the latter is a new mutation which has not been reported in previous studies. In another patient in whom the attempts to amplify exon 2 individually from genomic DNA were unsuccessful، PCR amplification of exon 2 revealed no band of this exon on agarose gel. A PCR amplification mix of exon 2 and exon 7، with an internal control، confirmed the lack of exon 2 in this patient. Although a gross deletion in other exons of NCF2 has been previously reported، a large deletion encompassing exon 2 has been not reported yet. This abstract was also presented in ESID 2012، Florence، Italy.

This study represents an attempt to determine the prevalence of exercise-induced bronchospasm among soccer player children. A total of 234 soccer player boys of all soccer schools from Shahr-Rey enrolled in this study. They did not have any history of a recent or chronic respiratory tract disease, a history of allergic diseases, and history of bronchodilator drugs consumption during the 24 hours prior to the study. Pulmonary function test (PFT) was performed for each participant before exercise and 6 and 15 minutes after playing soccer. The diagnosis of EIB was by a decrease in forced expiratory volume in 1 second (FEV1) by at least 10% and in peak expiratory flow rate (PEFR) by at least 15% with exercise challenge. If there was reduction in one parameter alone, the participants were considered as prone to EIB. Considering both FEV1 and PEFR the prevalence of EIB was 2.1% and 18.4% were prone to EIB. If FEV1 or PEFR tests were used as criteria for diagnosis of airway obstruction, the prevalence of EIB would be 6% and 15.8%, respectively. There was no significant difference between the post of players, family history of allergic disease and EIB in soccer players. This study suggests that at least 2.1% of soccer players will develop bronchospasm even if they do not have any history of asthma and allergy.