mohammad forghani

This study aimed to determine the psychometric properties of Persian version of Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ).

In addition to somatic symptoms and complaints, patients with irritable bowel syndrome have specific dysfunctional behaviors that lead to disease persistence and functional disturbance.

Participants included 170 patients with irritable bowel syndrome, who were diagnosed based on ROM-IV criteria and selected from patients referring to the Gastrointestinal Disorders Clinic, as well as 100 persons from the general populationin Isfahan in 2020. Both groups completed the 26-item Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ). Also, questionnaires including the Irritable Bowel Syndrome Symptom Severity Scale (IBS-SSS), Irritable Bowel Syndrome-Quality of Life IBS-QOL, Illness Perception Questionnaire (IPQ-R), Irritable Bowel Syndrome-Patient Satisfaction (IBS-SAT), Hope Scale, Interpersonal Forgiveness Inventory (IFI), and Dysfunctional Attitude Scale-26-item (DAS-26) were completed to determine the validity of IBS-BRQ. Tests of internal consistency, principal components analyses (PCAs), differentiation analysis, and correlation were used to determine its reliability, along with criterion and construct validity.

IBS-BRQ was valid and reliable in both groups with a high degree of internal consistency. Cronbach's alpha was obtained in the sample of patients with IBS and the total sample of participants 0.87 and 0.95 respectively. This scale differentiated significantly between IBS patients and non-patients (p<.001). The criterion validity was high as evidenced by a high correlation with DAS-26 (r=0.53, p<0.001), IBS-QOL (r=0.76, p<0.001), IBS-SSS(r=0.44, p<0.001), IPQ-R(r=0.56, p<0.001), and reverse correlation with IFI (r=-0.031, p<0.001), IBS-SAT(r=-0.23, p<0.001), and HOPE (r=-0.49, p<0.001).

The Persian version of the IBS-BRQ proved to be a well-defined behavioral response measure in IBS patients with high validity and reliability, making it a suitable measure to be used in future IBS clinical research in Iran.

The aim of this study was to evaluate the frequency and the sexual and age distribution of modifiable risk factors associated with acute coronary syndrome in patients admitted to one of the selected hospitals of police force.

This descriptive cross-sectional study was performed on all patients admitted to CCU of one of the selected hospitals of police force with the diagnosis of acute coronary syndrome during 2017-18. Baseline data on patients including sex, age, risk factors for acute coronary syndrome (including hypertension, hyperlipidemia, diabetes, smoking, opium use, and obesity) were collected. T-test and chi-squared test were respectively used for quantitative and qualitative variables comparison using SPSS 23. Finally, comparing the frequency of modifiable risk factors among the similar population in Iran and Turkey as well as population without acute coronary syndrome was done.

A total of 612 patients with acute coronary syndrome with mean age of 62.60±11.88 years (range 27 to 93 years) were enrolled that 349 persons(57.0%) were male. Hypertension (66.2%), hyperlipidemia (43.1%) and diabetes mellitus (42.0%) were the most common risk factors in the present study, respectively. There was a significant but inverse correlation between age and BMI (r=-0.179; p<0.001). The frequency of hypertension, hyperlipidemia, diabetes mellitus, obesity was significantly different from similar populations in Turkey and those without acute coronary syndrome in Iran. The frequency of hypertension and obesity was also significantly increased in the population with acute coronary syndrome in Iran, but hyperlipidemia and diabetes were not significantly different.

The most common modifiable cardiovascular factors among the selected population were hypertension, hyperlipidemia, diabetes mellitus and obesity. All four risk factors are more common in women than in men. Cigarette smoking and obesity are more common in younger patients and hypertensive in older patients.