فهرست مطالب mohammadamin serpoosh

Quality of life is a comprehensive concept related to physical health, psychological status, level of independence, social relations, personal beliefs, and environmental factors.  This study aimed to investigate the factors affecting the quality of life of students with disabilities in the universities of Kerman, Iran.

The present study was a descriptive cross-sectional study. The study population (n=307) consisted of students with disabilities in Kerman province selected by the census method. The required data were collected using a two-part questionnaire that included demographic characteristics and the World Health Organization Quality of Life Brief Version. The collected data were analyzed in SPSS19 software    using analysis of variance, t-test, and multivariate regression analysis.

The results showed that the total score of quality of life of the students was (46.4831±9.5117). Among the dimensions of quality of life, the highest mean score was related to social health (67.5207±20.69675), while the lowest mean score was obtained for general health (34.0798±21.01655). In addition, the quality of life of students was associated with gender,  education level, residence status, number of children in the family, family income, type of disability, and cause and severity of their disability (P<0.05). The results of multivariate regression analysis showed that residence status, family income, number of children in the family, and severity, cause, and type of disability significantly predicted the quality of life of students (R2=0.36).

This study provides useful evidence for identifying the factors that influence the quality of life and makes it possible to plan and implement appropriate health policies to improve the quality of life of students.

Epilepsy as a neurological disorder is characterized by unpredictable and periodic seizures. In the present study, the anticonvulsant effect of different doses of salep hydroalcoholic extract on pentylenetetrazole (PTZ) induced seizures was investigated.

Methods and Materials/Patients: 

The animal model of seizure was established by the intraperitoneal injection of pentylenetetrazole (PTZ- 85 mg/kg). Hydroalcoholic extract of salep was administered to the animals in 3 doses (80, 160, and 320 mg/kg). The parameters of the onset and duration of tonic-clonic seizure, total seizure time, balance (falling), and jumping during seizure mortality rate were measured. The results were analyzed by ANOVA test at a significant level of p≤0.05.

The results of the current study indicated that salep extract increased the delay in the onset of seizure in the PTZ + extract group in comparison with the PTZ group. The duration of tonic-clonic seizure and the number of falling, jumping, and total seizure times were significantly decreased by salep extract compared to the PTZ group. In the seizure + salep extract, the number and percentage of 24-hour mortality among animals decreased with increasing dosage. All changes were dose-dependent and 320 mg/kg showed the most effect.

  Extract of salep can probably have anticonvulsant properties, however, further studies are needed to clarify the exact mechanisms.