فهرست مطالب mozhgan hassan zadeh

Resistance training improves skeletal muscle function by affecting the proteins of the nervous system. However, there are conflicting results regarding the effects of resistance training on Neural cell adhesion molecule (NCAM) gene expression. Therefore, the present study aimed to investigate the effect of 4 weeks of increasing resistance training on NCAM gene expression in the gastrocnemius muscle of healthy male rats.

In an experimental trial, 12 young male rats were randomly divided into 2 groups of 6, including the control and resistance training groups. The training group performed increasing resistance training 5 days a week for 4 weeks on a special rodent ladder. Forty-eight hours after the end of the training intervention, the rats were sacrificed and the gastrocnemius muscle tissue was extracted for the expression of the NCAM gene using the real-time method.

resistance training in the neuromuscular junction, gastrocnemius muscle increased NCAM gene expression (P=0.036) compared to the control group.

Four weeks of resistance training can improve skeletal muscle function by increasing NCAM gene expression at the end of muscle fibers.

Regular exercise training with different volumes bydate palm pollen extract is an effectives strategy in improvinggene expression and neuromuscular function. The purpose ofthis study was to determine the Effect of four weeks ofincreasing resistance training with date palm pollen extract onthe gene expression of CHRN-G and Semaphorine-a3 in theGastrocnemius muscle of healthy male rats.

This is an experimental study. Forthis purpose, 42 six week old healthy of male rats were dividedinto 6 groups of numbers 7; Control (C), Resistance training(TR), Testosterone (T), SUP (S), Resistance training withextract (RT+SUP), Resistance training with Testostrone(RT+T). Extraction was performed with 90% ethanol at a rateof 670 ml and repeated three times. The extract wasconcentrated in vacuo and the solvent was completelyremoved. The extraction efficiency was 87.17%. Consumptionof the extract at a dose of 100 mg / kg per day to the extractgroups and exercise with the extract was gavagedintraperitoneally. Testosterone at a dose of 2 mg / kg per daywas injected into the testosterone and testosterone traininggroups.increasing resistance training, extract and testosteroneinterventions were performed for five days a week for fourweeks. After 24 hours the last training session and afterwardrecovery, subjects were sacrificed and their gastrocnemiusmuscle was extracted. PCR Real time was used to determinethe expression of CHRN-G and Semaphorine-a3 genes. tocompare the groups independent Two way anova was used atalpha level of 0/05.

genes expression of CHRN-G in the training withextract group (P=0.024) and training with testosterone(P=0.045) respectively showed a significant decreasecompared to the extract group. Semaphorine-a3 of gene in thetraining with extract group (P=0.016) respectively showed asignificant decrease compared to the extract group. Weight didnot significantly change in any of the groups.

It seems that possibly 4 weeks of increasingresistance training with consumption of date palm male pollenextract can improve neuromuscular function by reducing theexpression of CHRN-G and Semaphorine-a3 genes in thepresynaptic space.