فهرست مطالب nasir ali

HCV has very diverse genotypes in nature, divided into variable number of subtypes. Due to epidemiologically divergent subtypes, it shows diverse geographical distributions, which makes it difficult to treat. This disease plays havoc with underdeveloped and developing countries due to scarcity of data and poor awareness among common people. Therefore, this study aimed to evaluate the geographical distribution of HCV genotypes and RNA viral load along with hemato-biochemical analysis of HCV patients in underdeveloped and neglected areas of Punjab province, Pakistan.
Out of 1115 samples, 583 (52.3%) from males and 532 (47.7%) from females were declared as HCV RNA positive samples. In all the three regions, genotype 3 (46.3%) was found to be the most frequent genotype in both genders followed by genotype 2 (28.9%), genotype 1 (12.5%), genotype 4 (2.2%), genotype 5 (1.8%), genotype 6 (1.2%), untypeable genotypes (5.2%), and mixed genotypes (2.41%). Most of the patients had viral load less than 600,000 IU/mL.
HCV genotype 3a is the most prevalent genotype in various regions of Punjab. Effective HCV awareness programs and novel therapeutic measures should be enforced to combat against HCV infection. Moreover, geographical distribution and mapping of HCV in Pakistan should be studied to develop better control strategies against HCV infection.

The boundary layer flow of a third grade fluid and mass transfer near a stagnation-point with diffusion of chemically reacting species on a porous plate is investigated. Due to a porous plate the suction is taken into an account. Using suitable transformations, the momentum and concentration equations are first transformed into nonlinear ordinary ones and then solved using a hybrid numerical method. This method combines the features of finite difference and shooting methods. The effects of various controlling parameters on the flow velocity, concentration profile, skin friction and rate of mass transfer on surface are analyzed graphically and in tabular form. Comparison of the present results with the previous reported results has been found in excellent agreement.