فهرست مطالب neny purwitasari

Healers of Jamu- a Traditional Medicine in Solo City, Central Java, Indonesia apply several therapies for treatment of different diseases, including joint pain. The aim of the ethnomedicinal study is the identification of herbal formulations/ medicinal plants/method of preparation and their mode of administration for joint pain therapy in Jamu Medicine. An ethnomedicinal survey was conducted to collect data from traditional healers of Jamu Medicine regarding the practice of joint pain therapy. Data was collected from 25 healers through interview by snowball technique. The data obtained from the study revealed that, 25 herbal formulations /potions consisting of 32 types of medicinal plants from 19 families have been registered by traditional healers for joint pain therapy. Most commonly used plants for joint pain therapy have been identified as Piper retrofractum Vahl, Zingiber officinale Roscoe, Curcuma xanthorrhiza D.Dietr., Kaempferia galanga L., and Curcuma longa L. Traditional herbal formulations are prepared by different processing methods like washing, peeling, crushing, pounding then squeezing with warm water (infusion)/ boiling in water (decoction) to get their extract. These herbal formulations are administered orally or applied locally as massage on the affected joint. Through this study we will preserve the traditional knowledge of Jamu Medicine because the younger generation of traditional healers is no more interested in continuing it and their number is gradually decreasing. This valuable data will help the scientist to make new medicinal breakthroughs in the future especially to treat joint pain.

The world was startled in December 2019 by the emergence of an unprecedented pneumonia outbreak in Wuhan, China, with an unknown cause. However, on January 7, 2020, researchers successfully identified the responsible agent as a novel coronavirus. Meanwhile, the medicinal properties of bidara upas (Merremia mammosa Hall), a plant belonging to the Convolvulaceae tribe and commonly found in Indonesia and Malaysia, garnered attention due to its long history of use in traditional medicine for treating respiratory ailments. As a result, a study was conducted to investigate the antiviral potential of the ethanol extract of bidara upas against SARS-CoV-2. The research incorporated various methods such as cytotoxicity tests on the ethanol extract of bidara upas tuber, inhibition tests, RT-PCR, and plaque assays. Through toxicity tests, it was determined that a concentration of 500 ppm exhibited no harmful effects on cells. In the virus inhibition test using plaque assay, concentrations of 62.5 ppm, 125 ppm, 250 ppm, and 500 ppm demonstrated inhibition powers of 59.54%, 74.7%, 74.68%, and 79.27%, respectively. RT-PCR results varied across different concentrations, using the E and RdRp genes as references. CT values were increasing as compared to the negative control, indicating a decrease in viral load due to the sample treatment. Based on the findings of the virus inhibition test, RT-PCR, and plaque assay, it can be concluded that the ethanol extract of bidara upas tuber has potential as an antiviral agent against SARS-CoV-2.

The utilization of traditional medicine in Indonesia is highly prevalent and favoured by the Indonesian people for maintaining health and treating ailments, drawing upon the experience, knowledge, and skills of ancestors, family, or parents. Traditional medicine, known for its natural properties and minimal side effects, is extensively employed in local healing practices to address various diseases. This is evident in literary works like Serat Kawruh and Serat Centhini. In response to the pandemic, approximately 79% of Indonesia's population turned to medicinal plants to bolster their immunity during the COVID-19 outbreak. The Indonesian government also lends support by providing online resources in the form of books that offer recommendations on the usage of several medicinal plants. The literature review followed the PRISMA guidelines. Between April and June 2022, a literature search was conducted in many databases, including Scopus, Pubmed, NCBI, and EBSCO, with an article publication timeframe of 2012-2022. Some Indonesian medicinal plants may prevent and treat COVID-19. 1300 articles on SARS-CoV-2-fighting Indonesian plants were found in various databases. After the screening, 48 qualified scientific articles were found suitable for this review article. The results found that many Indonesian local plants have a potential effect as antivirals to inhibit COVID-19. However, further experimental and animal studies are needed to investigate the antiviral activities of each plant in vitro before proceeding with clinical trials in humans.