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عضویت

فهرست مطالب nosaibe seirfar

  • Nosaibe Seirfar, Javad Afsharmanesh, Amin Sadeghi Dousari, Ali Behzadi, Roohollah Mirzaee Khalilabad *
    Background

    Although today, transfusion therapy has turned from a hazardous condition to a relatively safe method with the improvement of technology, the highest risk for the patient is a complication of blood transfusions. This study aimed to evaluate the prevalence and pattern of transfusion-related adverse events.

    Materials and Methods

    This study is a retrospective review which examined data of all those who received blood transfusions at Kashani and Imam Khomeini hospitals of the south of Kerman province from 2014 to 2018 years.

    Results

    Of the total 16081 blood transfusions, 148 (0.92%) cases of blood complications were observed. Most cases occurred in males aged 31-40 and over 50 years, O blood group, injection packed red blood cell (PRBC) product, and within 20-60 minutes. Most of the transfusion-related complications were related to the surgery ward and in patients without underlying disease, and most complications included fever and chills.

    Conclusion

    The results of our study showed that the highest transfusion-related complications were fever and chills. Therefore, fever and chills in the early hours of transfusion should be considered as the most common transfusion-related complications.

    Keywords: Transfusion, Reactions, Complication, Blood}
  • مقدمه

    بندناف تک شریانی (SUA) در 6-5/0% از کل بارداری های جهان دیده می شود. اگرچه تاثیر SUA در بروز نقایص مادرزادی اجماع نظر نسبی وجود دارد ولی اختلاف نظرها در ارتباط با تاثیر آن بر پیامدهای بارداری هنوز باقی است.

    هدف

    این مطالعه با هدف تاثیر SUA بر پیامدهای بارداری و برآورد بروز آن در مناطق جنوبی ایران برای اولین بار انجام شد. ویژگی های اپیدمیولوژیک همراه با برخی اثرات آن بر نتایج بارداری/نوزادی نیز بررسی گردید.

    مواد و روش ها

    در این مطالعه مقطعی، داده های دو مرکز رفرال در جنوب ایران مورد تجزیه و تحلیل قرار گرفت. در مجموع 1469 بارداری، جنین و نوزاد از نظر ویژگی های مرتبط با SUA مورد بررسی قرار گرفتند. SUA با استفاده از تشخیص پاتولوژیک تعریف شد. نقایص مادرزادی با استفاده از نتایج معاینات بالینی، التراسونوگرافی و اکوگاردیوگرافی جمع آوری شدند. اطلاعات مربوط به نتایج بارداری بر اساس سوابق پزشکی بیماران ثبت گردید.

    نتایج

    شیوع SUA 47/3% (%6/4-6/2 :CI %95) بود. ناهنجاری های جنین از جمله ناهنجاری های کلیوی، قلبی و مادرزادی، مرگ داخل رحمی جنین، مرگ زودرس نوزادی، وزن کم هنگام تولد، وزن کم جفت و زایمان زودرس در گروه SUA به طور قابل توجهی بالاتر بود (به ترتیب 47/2 و 70/2، 22/3، 31/11، 85/3، 03/16، 04/31، 02/68 = OR). با این حال، تعداد مادران در گروه SUA کمتر بود (98/0-44/0 :CI %95، 65/0 =OR).

    نتیجه گیری

    ارتباط معناداری بین SUA و افزایش خطر مرگ داخل رحمی جنین و مرگ زودرس نوزادان و همچنین وزن کم هنگام تولد و تولد زودرس مشاهده شد. تاریخ زایمان مادر به عنوان عامل پیش بینی کننده مهم در SUA مشخص گردید. پیشنهاد می گردد مطالعات بیشتری در مورد طبقه بندی خطر نوزادان در این زمینه صورت گیرد.

    کلید واژگان: بند ناف, بندناف تک شریانی, پیامد بارداری, نقایص مادرزادی}
    Homeira Vafaei, Khatoon Rafeei, Maryam Dalili, Nasrin Asadi, Nosaibe Seirfar, Mojgan Akbarzadeh-Jahromi*
    Background

    Single umbilical artery (SUA) is found in 0.5-6% of all pregnancies, worldwide. Although the association of SUA with some of congenital malformations is mainly accepted, its effect on pregnancy/neonatal outcomes is still controversial.

    Objective

    This is the first study aimed to approximate the SUA prevalence in southern part of Iran. SUA epidemiologic features accompanied by some of its effects on pregnancy/neonatal outcomes are investigated as well.

    Materials and Methods

    In this cross-sectional study, data from two referral centers in Southern Iran were analyzed. In total, 1,469 pregnancies, fetus, and neonates were examined for epidemiological features associated with SUA. SUA was confirmed by pathological examination, while congenital anomalies were diagnosed by clinical, ultrasound, and echocardiographical examinations. Data on pregnancy outcome were recorded based on the patients’ medical records.

    Results

    The prevalence of SUA was 3.47% (95% CI: 2.6-4.6%). Fetal anomalies including renal, cardiac, and other congenital anomalies, intrauterine fetal death, early neonatal death, low birth weight, low placental weight, and preterm birth were significantly higher in the SUA group (OR = 68.02, 31.04, 16.03, 3.85, 11.31, 3.22, 2.70, and 2.47, respectively). However, the maternal multiparity was lower in the SUA group (OR = 0.65; 95% CI: 0.44-0.98).

    Conclusion

    A significant association was observed between SUA and increased risk of intrauterine fetal death and early neonatal death, as well as low birth weight and preterm birth. Obstetrical history of the mother like parity was identified as an important predictor of SUA. Further investigations are suggested on risk stratification of neonates in this regard.

    Keywords: Umbilical cord, Single umbilical artery, Pregnancy outcome, Congenital abnormalities}
  • Roshanak Aliakbar, Navahi, Mohammad Javad Ashraf, Nosaibe Seirfar, Samaneh Koohestani, Elham Abedi
    Purpose
    To determine the prevalence of various types of conjunctival lesions, at a tertiary ophthalmic center in Fars Province, South of Iran.
    Methods
    Histopathologic slides and medical records of conjunctival lesions submitted to the pathology department of Khalili Hospital, Shiraz, Iran were reviewed from April, 2009 to July, 2013. The histopathologic diagnoses were categorized into benign, pre-malignant, and malignant lesions. The prevalence of various types of conjunctival lesions was calculated.
    Results
    Histologic sections of 631 conjunctival lesions were reviewed. Benign lesions were most prevalent (81.8%), followed by premalignant (10.8%) and malignant (7.4%) lesions. Pterygia were the most common benign lesions (69.2%), intraepithelial dysplasia constituted most cases of premalignant lesions (94.1%), and squamous cell carcinoma was the most frequent malignant lesion (93.6%). Benign lesions were the most common type of lesions in all age groups, however the prevalence of malignant lesions increased significantly with age (P < 0.001).
    Conclusion
    Benign lesions were the most common conjunctival lesions with pterygia on top of the list, while intraepithelial neoplasia and squamous cell carcinoma were the most common premalignant and malignant lesions, respectively. Conjunctival malignant lesions were more prevalent with older age.
    Keywords: Conjunctival Lesions, Intraepithelial Dysplasia, Squamous Cell Carcinoma}
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