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فهرست مطالب reyhane ghanbari

  • Reyhane Ghanbari, Kourosh Mojtahedi, Pirouz Samidoust
    Introduction

     Liver transplantation is a widely distinguished and highly practical therapy for liver cirrhosis. In any case, liver transplant surgery assumes a risk of influential complications. In this way, the survival rate of liver transplant patients at Razi Healing Center in Rasht from 2017 to 2022 was investigated.

    Materials and Methods

     In this retrospective cohort study, liver transplant patients referred to Razi Hospital in Rasht, Iran, from 2017 to 2022 were studied. Patient demographic and clinical information were collected. Survival was determined using Kaplan-Meier estimates. Log rank was used to determine differences between study groups in survival.

    Results

     Out of 46 patients who underwent liver transplantation surgery, 54.3% of patients survived. Also, the most common causes of death for the samples of this study were COVID-19 and hemorrhage. Patients with autoimmune cirrhosis due to hepatitis have a significantly higher risk of death than those with cirrhosis due to other factors. Postoperative vascular thrombosis was found to be significantly associated with reduced patient survival. Patient outcomes improved significantly in the second part of the six-year liver transplant study. The study highlights the importance of increasing experience in liver transplant surgery and postoperative care to improve outcomes.

    Conclusion

     According to the results of this study, patients with autoimmune cirrhosis due to hepatitis have a higher risk of death than those with cirrhosis due to other causes. In addition, postoperative vascular thrombosis is believed to significantly reduce patient survival. The study highlights the importance of increasing experience in liver transplant surgery and postoperative care to improve outcomes for these patients.

    Keywords: Liver transplant, Surgery, Survival, Liver failure}
  • Elham Ramezanzade, Reyhane Ghanbari *, Tina Yazdanipour
    Introduction

     There has been a rise in the reappearance of multidrug-resistant Gram-negative bacteria in recent years. Using polymyxins, such as colistin, as a last-line treatment for these infections has led to renewed interest in the toxic effects of this drug.

    Case Presentation

     In this case report, we present neurological signs and symptoms developed in a patient with a history of cervical cancer four to five hours after receiving colistin for treating a urinary tract infection caused by MDR Pseudomonas aeruginosa with a colony count of > 100,000/L. These signs and symptoms included lower limb hemiparesis, facial paresthesia, decreased deep tendon reflexes, and tinnitus, which were resolved on their own 24 hours after discontinuation of the drug. Antibiotic therapy was continued with pipractate and ciprofloxacin instead. The patient got discharged in stable condition after negative urine culture results.

    Keywords: Colistin Toxicity, Neurotoxicity, Urinary Tract Infection, Antibiotic Therapy}
  • Elham Ramezanzade, Reyhane Ghanbari *, Tina Yazdanipour
    Introduction

     There has been a rise in the reappearance of multidrug-resistant Gram-negative bacteria in recent years. Using polymyxins, such as colistin, as a last-line treatment for these infections has led to renewed interest in the toxic effects of this drug.

    Case Presentation

     In this case report, we present neurological signs and symptoms developed in a patient with a history of cervical cancer four to five hours after receiving colistin for treating a urinary tract infection caused by MDR Pseudomonas aeruginosa with a colony count of > 100,000/L. These signs and symptoms included lower limb hemiparesis, facial paresthesia, decreased deep tendon reflexes, and tinnitus, which were resolved on their own 24 hours after discontinuation of the drug. Antibiotic therapy was continued with pipractate and ciprofloxacin instead. The patient got discharged in stable condition after negative urine culture results.

    Keywords: Colistin Toxicity, Neurotoxicity, Urinary Tract Infection, Antibiotic Therapy}
  • Elham Ramezanzade, Reyhane Ghanbari *, Tina Yazdanipour
    Introduction

    Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is a group of multisystemic autoimmune diseases that can involve organs such as kidneys and respiratory tracts. Since the initiation of COVID-19 vaccines, there have been few cases of antineutrophil cytoplasmic antibody (ANCA) glomerulonephritis development after receiving vaccine doses.

    Case Presentation

    This report describes a 15-year-old man who has developed ANCA-associated glomerulonephritis (AAGN) after receiving the second dose of BBIBP-CorV (Sinopharm) COVID-19 vaccine.

    Conclusions

    Development of AAGN after both natural SARS-CoV-2 infection and following other vaccinations raises the question of the possible causality between the two. Considering the widespread use of COVID-19 vaccines, it is highly important to investigate their possible side effects.

    Keywords: Antineutrophil Cytoplasmic Antibody, Glomerulonephritis, SARS-CoV-2}
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