فهرست مطالب rikhtehgar m.h

To report a case of periocular xanthogranuloma with adult-onset asthma in Hodgkin Lymphoma association with intermediate uveitis.

A 51-year-old man presented with the complaint of blurred vision in both eyes and bilateral periocular masses. He had a history of Hodgkin lymphoma treated by chemotherapy 10 years ago with no recurrence. Respiratory problems with small periocular nodules occurred 3 years after completion of chemotherapy. Multiple incisional biopsies were all negative for recurrence of lymphoma. Anti-asthma therapy was started for the patient with close follow-up. During past years, periocular and upper eyelid nodules enlarged very slowly leading to severe mechanical ptosis and bilateral intermediate uveitis and uveitic macular edema emerged. Excisional biopsy was done and the diagnosis of xanthogranuloma was confirmed by pathology exam. No recurrence was seen after 6 months.

History of Hodgkin lymphoma and chemotherapy may predispose the patient to future inflammatory disorders like Periocular xanthogranuloma with adult-onset asthma and intermediate uveitis.

To report a rare case of solitary myofibroma involving the sclera in an elderly person.

The patient was a 93 -year-old man complaining of a mass lesion in the lateral sclerolimbal area of his left eye; the lesion had enlarged suddenly since 20 days ago. Other examinations (including skin, heart, and ext) and lab data (CBC, Lipid profile, liver, and kidney function) were normal. The only medical history was laryngeal cancer with a history of radiotherapy 15 years ago. The tumor was excised completely. Histopathology reported solitary myofibroma. During two months of follow-up, no sign of recurrence was found.

Solitary myofibroma of the sclera may be a differential diagnosis of epi-bulbar masses, including squamous cell and peduncular squamous cell carcinomas, especially in patients with a history of cancer and radiation therapy.