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عضویت

فهرست مطالب roshanak saghebi

  • Marjan Akhtari, Morteza Mojahedi, Narjes Gorji, Ali Bijani, Seyyed Ali Mozaffarpur, Roshanak Saghebi, Reihaneh Moeini*
    Background Introduction

    Mizaj is the basis of attention to individual differences in Persian Medicine (PM). Regarding the importance of Mizaj for health preservation and treating diseases, it is necessary to achieve a standard tool for Mizaj identification. The purpose of this study was to design a standard self-reporting Mizaj identification questionnaire for elders.

    Methods

    In this exploratory sequential study, criteria of Mizaj identification were extracted by reviewing PM literatures and interview with PM experts and elders. The primary questionnaire was designed and its validity and reliability were assessed, using weighted Kappa statistics, Pearson correlation coefficient (PCC) assessment, receiver operating characteristic (ROC) curve and determining the specificity and sensitivity of cut-off points.

    Results

    Among the 101 items in the primary questionnaire, 73 items had acceptable reliability. The final 20-item questionnaire was obtained after the criterion validity and PCC assessment. The sensitivity and specificity of this questionnaire were 83% and 88% for warmness, 49% and 80% for moderate in warmness-coldness, 72% and 91% for coldness, 57% and 78% for wetness, 30% and 79% for moderate in wetness-dryness, and 81% and 67% for dryness, respectively.

    Conclusion

    The first standard Mizaj identification questionnaire for elders was designed in this study. It is recommended as a supplementary diagnostic tool for clinicians and researchers in PM. Also, the people with age over 60 can use it to identify their own Mizaj and then, choose the suitable PM or Unani medicine lifestyle recommendations based on their Mizaj.

    Keywords: Mizaj, Persian Medicine, Questionnaire, Temperament, Unani medicine, Validation assessment}
  • Morteza Mojahedi, Roshanak Saghebi, Nargess Gorji, Reihaneh Moeini, Seyed Reza Hosseini, Ali Bijani, Reza Ghadimi, Seyyed Ali Mozaffarpur*, Hoda Shirafkan
    Background

    One of the principles of Persian medicine (PM) is the individualized approach that is presented with the concept of Mizaj. In this viewpoint, Mizaj is determined for every person based on 10 criteria, which is a result of the Mizaj of the main organs, including the brain, liver, and heart. There is no standard diagnostic tool for Mizaj assessment in the elderly. The purpose of this study is to explain the method of Mizaj assessment and data analysis in the elderly in the second phase of the Amirkola health and aging project (AHAP) in Iran.

    Methods

    In this study, a novel Mizaj assessment method in two phases is presented. In the first phase, 1541 elderly were assessed by a PM expert and typical diagnoses were determined. At the second phase, an expert panel including 5 PM experts evaluated the cases. The paraclinical and metric data of the elderly whose Mizaj agreed in the expert panel was used to assess its correlation with Mizaj.

    Conclusion

    In the lack of valid and reliable questionnaires to assess the personalized viewpoint of PM, a new expert-based method has been introduced that can be used in similar studies. The result of the Mizaj assessment in this way will be used to obtain objective values for the Mizaj assessment.

    Keywords: Geriatrics, Cohort Studies, Medicine, Traditional, Complementary Therapies, Temperament, Precision Medicine}
  • Hossein Salmannezhad, Morteza Mojahedi, *, Abbas Ebadi, Seyyed Ali Mozaffarpur, Abbas Alipoor, Roshanak Saghebi, Ali Montazeri
    Background
    Paying attention to individual differences in presenting health directives is the most important properties of Persian Medicine (PM). Accordingly, individuals in each society are divided into nine Mizaj groups. Access to the standard diagnostic scale is one of the research priorities of PM.
    Objectives
    The present study aimed at designing a preliminary self-administered Mizaj questionnaire, and assessed its reliability and validity.
    Materials and methods
    For this exploratory sequential study, Mizaj identification indices were extracted using PM references, and people and PM experts’ interviews. The preliminary questionnaire was designed and the validity and reliability of the questionnaire were evaluated using weighted Kappa statistics (> 0.4), ICC and ROC curve, and determining the sensitivity and specificity of cut-off points.
    Results
    Overall, 15 PM experts, and 221 volunteers participated in various stages of this study. Among 119 designed questions for 30 Mizaj identification indices, 60 items had acceptable reliability. The final questionnaire containing 20 items was extracted after the validity assessment. The sensitivity and specificity of this questionnaire at the specified cut-off points were 71% and 68% for warmness, 63% and 71% for temperance in warmness-coldness, 80% and 57% for coldness, 74% and 58% for wetness, 71% and 69% for temperance in wetness-dryness, and 78% and 85% for dryness, respectively.
    Conclusions
    This is the first standard Mizaj identification questionnaire, which includes more dimensions of Mizaj identification and can be used for individuals aged 20 to 60 years old. This questionnaire is recommended for Mizaj identification researches and as a supplementary diagnostic scale for clinical activities of Persian Medicine practitioners.
    Keywords: Precision Medicine, Questionnaires, Reproducibility of Results, Temperament, Validation Studies}
  • Morteza Mojahedi, Abbas Alipour, Roshanak Saghebi, Seyyed Ali Mozaffarpur *
    Background
    As personalized medicine is developing, similar concepts in Persian medicine need standardization.
    Objectives
    The aim of this study was to compare the correlation of ten criteria of Mizaj assessment with Mizaj determined by experts.
    Methods
    In this cross-sectional methodological research, 74 medical student volunteers were examined by 10 expert raters. The agreement between each ten indices and total Mizaj were assessed with the spearman correlation coefficient (r) and weighted by the kappa coefficient (wk).
    Results
    Among ten indices, the largest agreement was observed amongst indices of psychic function, impressibility, physical function and physique with total warm or cold Mizaj and thus amongst indices of muscle and fat mass, touch and physique with total wet or dry Mizaj, respectively (k ≥ 0.4).
    Conclusions
    The four mentioned indices in assessing warmness-coldness and three in wetness-dryness are major criteria. Other indices, such as hair condition, skin color, quality of waste matter (stool, urine, and sweat), and sleep/wakefulness have minor effect in Mizaj identification.
    Keywords: Medicine, Traditional, Temperament, Reproducibility of Results}
  • Hossein Salmannezhad, Morteza Mojahedi *, Abbas Ebadi, Ali Montazeri, Seyyed Ali Mozaffarpur, Roshanak Saghebi, Davood Gheisari, Sajad Goudarzi
    Background
    Mizaj (Temperament) is one of the fundamental concepts of Persian Medicine (PM) and identifying this concept is crucial for providing various healthcare recommendations and for the treatment of patients. In PM, various indices can indicate a person’s Mizaj, one of them is the happiness of people. From this perspective, people with warm Mizaj are happier than people with cold Mizaj.
    Objectives
    The aim of this study was to assess the correlation between happiness and Mizaj.
    Methods
    In order to conduct this Cross Sectional (descriptive-correlational) study based on convenience sampling method, 610 participants completed the 29-item Oxford Happiness Questionnaire (OHQ) and the 10-item Mojahedi Mizaj questionnaire (MMQ). The study started since September, 2016 and ended in November, 2016 in Tehran, Iran. The collected data were compared by chi-squared test.
    Results
    The frequency of happy individuals in warm, temperate, and cold Mizaj groups was 85.2%, 79% and 58.2%, respectively. According to the results of chi-squared test, individuals with cold Mizaj were significantly less happy than people with warm and temperate Mizaj. However, there was no significant difference between warm and temperate Mizaj groups. Moreover, the level of happiness in people with wet Mizaj was not significantly different from people with dry Mizaj.
    Conclusions
    There is a significant correlation between happiness and an individual’s Mizaj. Accordingly, one of the hypotheses regarding indices of Mizaj identification in PM is strengthened. This index can be used in researches associated with designing and validating Mizaj evaluative scales in PM to differentiate cold and warm Mizaj.
    Keywords: Temperament, Happiness, Traditional Medicine}
  • Seyyed Ali Mozaffarpur, Roshanak Saghebi, Soraya Khafri, Morteza Mojahedi
    Although Mizaj (temperament) as a basic concept is introduced by ten criteria in Persian Medicine (PM), methods of assessment and priorities of these criteria are unclear. Having expert teams with an acceptable consensus in clinical diagnosis is one of the basic requirements to design and standardize Mizaj diagnostic scales. In this cross-sectional study, three PM specialists assessed the Mizaj of 150 healthy volunteers. At the first step of this study, each participant was separately visited by raters to determine warmness-coldness and wetness-dryness. To assess the agreement between experts, Intraclass Correlation Coefficient (ICC), weighted kappa (wk) and Spearman correlation Coefficient (r) were calculated. At the second step in an expert panel discussion, agreed criteria in 10 criteria of Mizaj identification were extracted. ICC between expert was 0.62 (CI: 0.53-0.73) in warmness-coldness and 0.64 (CI: 0.56-0.72) in wetness-dryness. Wk and r between every two experts were in the range of 0.41-0.60 and 0.58-0.67, in warmness-coldness and in the range of 0.49-0.61 and 0.58-0.69 in dryness-wetness, respectively. In determining warmness-coldness of Mizaj, psychic function, impressibility speed, muscle and fat mass, physical functions and touch condition were mostly used. In addition, muscle and fat mass, touch and sleep condition were mostly used in regard with dryness-wetness aspect of Mizaj. The agreements between three experts seem acceptable. It can be concluded that the weights of 10 criteria for Mizaj assessment in PM are not equal. The aims of the future studies in this field can be weighing these criteria.
    Keywords: Traditional Medicine, Reliability, Iranian medicine, Temperament}
  • سیدعلی مظفرپور، مرتضی مجاهدی، روشنک ثاقبی، زینب محمودپور*
    نفخ شکم یکی از شایع ترین شکایات عمومی و از جمله شایع ترین بیماری های گوارشی محسوب می شود. با توجه به اثرات متناقص درمان های ارائه شده جهت درمان نفخ در طب رایج و اهمیت تجارب سنتی در ساخت داروهای موثر، این مقاله به معرفی مفردات موثر بر نفخ شکم از دیدگاه طب سنتی ایران پرداخته است.
    این تحقیق یک مطالعه کتابخانه ای و بر اساس بررسی متون طب سنتی می باشد. در این مطالعه مفردات دارویی موثر در درمان نفخ شکم در شش کتاب مرجع داروشناسی طب سنتی (الابنیه عن حقایق الادویه، قانون فی الطب، اختیارات بدیعی، تذکره داوود انطاکی، تحفه حکیم مومن، مخزن الادویه) جستجو شد. این کار در ده مرحله (یافتن کلیدواژه، یافتن مفرده، جستجو در منابع، تهیه لیست واحد، یافتن مترادف ها، دسته بندی، بازبینی، خروج مفردات از ترکیبات، جمع بندی، نمره دهی، مرتب سازی) انجام شد. در پایان این مراحل، بر حسب نمره کسب شده، 302 مفرده دارویی مطرح در درمان نفخ شکم یافت شد. بیشترین نمره کسب شده (امتیاز 10) برای سه مفرده (اگیر ترکی، زنیان، سیاه دانه) در درمان نفخ شکم به دست آمد و بیشترین تعداد مفردات موثر بر نفخ، در کتاب مخزن الادویه می باشد. لیست مفردات دارویی حاصل شده در این مطالعه می تواند مبنای انجام مطالعات بالینی برای ساخت داروهای جدید در درمان نفخ شکم قرار گیرد.
    کلید واژگان: نفخ, طب سنتی ایرانی, مفرده دارویی}
    Seyyed Ali Mozaffarpour, Mortaza Mojahedi, Roshanak Saghebi, Zeinab Mahmoudpour*
    Abdominal bloating is one of the most common general symptoms and digestive complaint. In addition to contradictory effects of bloating treatment and importance of traditional experiments on product of effective drugs, this study presents effective plants in traditional medicine. This study is a review and searched effective medical plants on abdominal bloating on 6 books (Al Abnieh Anhaghayegh Al Advieh, Canon fe Teb, Ekhtiarat Badiei, Tazkere Davod Antaki, Tofat ol moeminin, Makhzak ol Advieh). This plan was done on 10 steps (finding key words, finding materia medica, searching on references, taking same list, finding equivalents, grouping, reseeding, extract of singular of complexes, adding, scoring, ranking). The last of study was detected 302 effective medical plants on abdominal bloating. Maximum score was 10 (Acorus Calamus, Carum Copticum, Nigella Sativa) and Makhzan Al Advieh had maximum effective plants. List of medical plants can be base of clinical studies for producing new drugs on abdominal bloating treatment in this study.
    Keywords: Flatulence, Traditional Persian Medicine, Materia Medica}
  • الهام بهمنش، مرتضی مجاهدی، روشنک ثاقبی، محمدحسین آیتی، حمیدرضا بهرامی طاقانکی، زینب محمودپور، حسام الدین علامه، حسین سلمان نژاد، سیدعلی مظفرپور*
    Elham Behmanesh, Morteza Mojahedi, Roshanak Saghebi, Mohammad Hossein Ayati, Hamid Reza Bahrami Taghanaki, Hesameddin Allameh, Hosein Salmannezhad, Zeinab Mahmoudpour, Seyyed Ali Mozaffarpur*
    Traditional medicines, according to the World Health Organization, are defined as “the sum total of the knowledge, skill, and practices based on the beliefs, theories, and experiences indigenous to different cultures that are based and developed historically. Due to the increasing uses of traditional medicines worldwide, it seems that cognition of their principles and foundations are necessary.” The two important schools of Traditional Persian Medicine (TPM) and Traditional Chinese Medicine (TCM) have many similar concepts; one of the most fundamental is the theory of Arkan in TPM and theory of five elements in TCM. This is a review study, which extracted, classified and compared related concepts in TPM and TCM, conducted on original sources. To use the experience of other researchers and to find published articles in this regard, the Web databases SID, Magiran, Iranmedex, Google scholar, Pubmed and Embase were searched. The results are categorized under 12 categories. Generally, although there are considerable similarities between theory and functions of Arkan in TPM and theory of five elements in TCM, there are differences between the basic principles and the outcomes of these two theories. The comparison between these two theories shows that although they derive from similar theoretical and philosophical origins, that TPM arises from a monotheistic (not necessarily Islamic) viewpoint while TCM comes mostly from a metaphysical point of view. Furthermore, there are four principles in TPM but five in TCM. In addition, principles in TCM and TPM differ as follows: while in the former, the principles (having interactions in a dynamic process) are assumed to be directly related to phenomena, in the latter, they are explained with the mediated concept of “Mizaj”.
    Keywords: Traditional Persian Medicine, Traditional Chinese medicine, Arkan Theory, Five Elements Theory}
  • Hajar Salmalian, Roshanak Saghebi, Ali Akbar Moghadamnia, Ali Bijani, Mahbobeh Faramarzi, Fatemeh Nasiri Amiri, Fatemeh Bakouei, Fereshte Behmanesh, Reza Bekhradi
    Background
    Dysmenorrhea is one of the most common medical problems in gynecology causing several problems in the personal and social life of women. This study was conducted to compare the effect of thymus vulgaris and ibuprofen on the treatment of primary dysmenorrhea
    Methods
    This clinical study was conducted on 84 students of Babol University of Medical Sciences with primary dysmenorrhea. The students were randomly assigned to three groups receiving thymus vulgaris, ibuprofen and placebo. In all three groups, with the beginning of pain, 200 mg capsules and 25 drops of essential oil were given every 6 hours for two consecutive cycles. Pain intensity used the visual scale before and one h after each dose for 48 h after starting medication. The data were collected and analyzed. This study was registered in the Iranian Registry of Clinical Trial (www.irct.ir) with registration number ID: IRCT201101245683N1
    Results
    The mean age of participants was 20.5±1.8 years. Both thymus vulgaris and ibuprofen were effective to reduce the pain severity of dysmenorrhea. Before treatment, using a linearly-visual pain scale, the mean pain intensity in thymus vulgaris, ibuprofen and placebo groups were 6.57±2.02, 5.30±2.23 and 6.18±1.78, respectively and after treatment decreased to 1.21±1.06, 1.48±1.62 and 3.54±2.26, respectively. Reduction of pain severity was not statistically significant between the two medications; however, it was significant for each drug compared with placebo (p<0.001).
    Conclusion
    The results suggest that thymus vulgaris as well as ibuprofen can be effective in reducing the severity of pain and spasm in primary dysmenorrhea
    Keywords: Thymus vulgaris, Primary dysmenorrhea, Iboprofen}
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