فهرست مطالب sahar fadaei

Postpartum depression appears to be a harmful condition affecting mothers and their babies negatively. Regarding their side effects, the tendency to use antidepressants has especially fallen in nursing mothers. Considering the effect of zinc on mood, this study was conducted to determine the efficacy of zinc oxide nanoparticles on postpartum depression in female mice.
Material & In this experimental study, the adult female mice of NMARI breed (25-30gr) were divided into six groups respectively (n=8): 1) Control 2) Depressed group 3, 4, 5) Depressed groups treated with a dose of zinc oxide nanoparticles including (5, 10 and 20 mg/kg) 6) Depressed groups treated for 8 days with a dose of 5 mg/kg zinc oxide nanoparticles.
First, the studied animals were depressed by intraperitoneal injection of 5mg/kg progesterone for 5 days. The control group received no drug or solvent. The assessment of depression rate on the eighth day after the start of administration of progesterone was conducted by forced swim test.
The zinc oxide nanoparticles at doses 10 mg/kg (P Administration of progesterone induces depression, and thus, increases the period of immobilization of mice. The zinc oxide nanoparticles reduced the symptom of postpartum depression in forced swim test. The findings can be used to show the effects of zinc oxide nanoparticles in the reduction of postpartum depression.

Background and Cerebral venous thrombosis (CVT) is the thrombosis affecting cerebral veins and sinus and is a rare condition. The diagnosis may be late or neglected due to the great clinical spectrum of symptoms, various forms of initial presentation and unspecific signs of neuroimaging. In this descriptive study, the included patients were followed up according to clinical manifestations, diagnostic efforts and clinical suspicions. The information regarding the subjects’ age, gender, clinical presentation, diagnostic efforts and classified treatment results were recorded. The data was obtained during a 21 months period and analyzed in SPSS. The most prevalent symptoms among the study population were headache, papillary edema, blurred vision, sensory-motor disorder, disorders of consciousness, double vision, behavioral disorder, speech impairment, focal seizure, and generalized seizure. The most common reasons were taking oral contraceptive pill (OCP), pregnancy, infection, idiopathic, drug abuse, hematologic diseases, trauma, previous cerebrovascular accident, CVT, diabetes, and hypertension. The most prevalent complaint was headache and the most founded neurological sign was papillary edema. In our study, OCP and pregnancy were the greatest etiologies, while infection was the next common etiology.

Migraine Induced Stroke (MIS) is an important cause of brain infarction in the young people. Consecutive patients with MIS admitted in Ghaem hospital, Mashhad during 2006-2010 enrolled a prospective clinical study. All of the patients suspected to MIS had brain MRI with a 0.5 Tesla generation, Philips NT Intra, Netherland. All of the MIS patients underwent a standard battery of diagnostic investigations for detecting etiology of stroke. Disability of MIS patients was detected based on the modified Rankin scale at 90 days post stroke. 32 MIS patients (18 females, 14 males) with mean age 37.2 ± 3.8 years ranged 15-58 years were evaluated. Hypodense area of infarction corresponding to clinical manifestations was detected in MRI in 32% of our MIS patients. The mean disability score in our MIS patients was 1.09 ± 0.32, which is significantly lower than other stroke patients (z = 2.55, P = 0.007) MIS is an important cause of stroke in Persian young adults which have good prognosis.