فهرست مطالب saied saeidimehr

 The relationship between various blood glucose-lowering treatments for type 2 diabetes mellitus (T2DM) and the mortality and complication rates of COVID-19 infection holds significant relevance.

 This retrospective study aimed to investigate the clinical progression of COVID-19 in T2DM patients previously treated with sitagliptin, metformin, or a combination of both.

 The study reviewed the medical records of T2DM patients with COVID-19 who had received treatment with sitagliptin, metformin, or both. Participants were selected from those admitted to Naft Hospital in Ahvaz, Iran, from March 2020 to March 2022. Data on mortality and adverse outcomes related to COVID-19 were gathered from the medical records.

 The study included 529 diabetic patients treated with metformin (n = 197), sitagliptin (n = 231), or both (n = 101) for a minimum of three months. The overall mortality rate among diabetic patients was 15.1%, with the metformin group showing the highest mortality rate at 28.9% (P < 0.0001). Significant differences were observed among the three treatment groups in terms of the frequency of acute respiratory failure (P < 0.0001), stroke (P = 0.002), pulmonary embolism (P < 0.0001), and the necessity for ICU admission (P < 0.0001). Nonetheless, the incidence of myocardial infarction did not significantly differ between the groups.

 The findings suggest that sitagliptin use for blood sugar control in T2DM patients may help reduce adverse outcomes and the risk of death due to COVID-19. Mortality and morbidity rates were found to be higher in patients treated with metformin compared to those in the other groups.

 The aim of the present study was to assess clinical characteristics, management, and in-hospital outcomes of COVID-19 among oil refinery workers in a single referral center.

 This cross-sectional study was conducted in a non-COVID single referral center from March to August 2020. At the Naft Grand Hospital, a COVID-19 specimen collection and molecular detection unit was established, and staff were trained how to collect suitable samples (sufficiently deep swabs), store, pack, and transport them. The diagnosis of COVID-19 infection (SARS-CoV-2) was confirmed by real-time reverse transcription polymerase chain reaction (RT-PCR).

 Overall, 500 patients with confirmed COVID-19 infection were included, among whom the most common comorbidities were hypertension (52.2%) and diabetes (45.6%). Moreover, 298 patients (59.6%) had one to three comorbidities; 148 patients (29.6%) had four to six comorbidities, and two patients (0.4%) suffered from seven and more comorbidities. Out of these, 23 patients (4.6%) had cancer, and 206 (41.2%) suffered from other diseases. Most of the patients (390, 78.8%) received Kaletra, and 387 (78.02%) were treated with Azithromycin. Overall, PCR results were positive in 377 (75.4%) patients; computed tomography scan (CT-scan) was positive in 413 (82.6%), and CRP test rendered positive results in 335 patients (67%).

 Most referred cases were survivors with mild to moderate symptoms, and a few of them were unfortunately non-survivors. This could be due to the appropriate responses to treatment and institutional isolation of people with mild COVID-19 symptoms. Thus, good and evidence-based clinical care combined with intense public health interventions will save the lives of thousands, if not millions, worldwide.

Nosocomial infections have increasingly resulted in death and the patients should bear high treatment costs. Members of the medical team could play an important role in prevention and control of nosocomial infections The purpose of this research was the evaluation of nosocomial infections in patients admitted to Naft grand hospital in Ahvaz, Iran, during 2013.Patients and This was a descriptive study, conducted prospectively during 12 months from March 2013 to March 2014 in Naft grand hospital in Ahvaz, Iran. All the patients who were hospitalized with no signs and symptoms of infection before the first 48 hours of hospitalization and presenting signs and symptoms of infection after 48 hours of hospitalization were included in this study. The patients’ age, gender, site of infection, ward of hospitalization and type of nosocomial infection were collected. The results were analyzed by Excel and SPSS 16.0. The results of the present study showed that the incidence of nosocomial infections was low (i.e., < 2%). The incidence rates of nosocomial infections were 36.78% in the intensive care unit (ICU), 46.55% in the internal medicine ward, 14.94% in the surgical medicine ward and 1.72% in the coronary care unit (CCU). Regarding the etiology of infection, Escherichia coli was found in 43.10%, coagulase-positive Staphylococci in 17.24%, coagulase-negative Staphylococci in 14.95% and Klebsiella in 10.34% of the cases. In our hospital, E. coli was the most frequent pathogen. In this study, nosocomial infections had a lower frequency in comparison with the national rates. According to researches, hospitals have been able to reduce nosocomial infections by establishing strategies and getting the risks under control.

Sulfur dioxide has been widely studied among the human- made pollutants. Air pollution is a major environmental risk to health. The less air pollution, the better the cardiovascular and respiratory health of the population will be, both long- and short-term. several studies have demonstrated relation between on short and long term effects exposure to air pollutants with human health. The exposure to sulfur dioxide is extremely risky for people health because these compounds enter the circulatory system directly through the airways. Sulfur dioxide can be absorbed into your body through your nose and lungs. The most important effects of sulfur dioxide air pollution include: increase rates hospital admissions, asthma attacks, cardiopulmonary disease, death and number of the years of life lost. Sulfur dioxide can be dangerous to the respiratory system and the functions of the lungs and can also lead to irritation of eyes. Ahvaz as the center of east khouzestan province in southwest of Iran is a one of the most populated and polluted cities. Ahvaz city, with a population of 1 million approximately, with an area of 8152 square kilometers, the capital city of Khuzestan Province is located between 48 degree to 49°29′ east of Greenwich meridian and between 31 degrees and 45 minutes to the north of the equator. Ahvaz is located in an arid area in south west of Iran with long and hot summertime. Temperature reaches to 50 degree of centigrade on June and July. Keep in mind, high density of industries (steel, oil and gas) makes Ahvaz as one of most important emitter. With the rapid economic growth in Ahvaz, the level of air pollution from both motor vehicles and industrial emissions has drastically increased. Furthermore, health effect of air pollution in terms of Sulfur dioxide, ozone and particulate matter in most of megacities particularly Ahvaz was reported. This research aims to estimate the health effects (total of death, cardiovascular and respiratory mortality) related to Sulfur dioxide pollutant in 2011. In this retrospective study, was used to assess the potential effects of Sulfur dioxide exposure on human health in Ahvaz city (located in south-western Iran) during year 2011.The concentration of Sulfur dioxide pollutant was measured in 2011 in four stations in Ahvaz. The most important part of analysis is data processing that encompasses modification of temperature and pressure, primary processing (the deletion, spreadsheet and synchronization), secondary processing (writing code and condition correction), formulation and filtering. Finally, Estimate of health effects related to Sulfur dioxide pollutant in the cur of Ahvaz. We calculated health effects related to Sulfur dioxide by AirQ2.2.3 based on the utilizing relative risk, attributable proportion and baseline incidence from WHO data. This model includes four screen inputs (Supplier, AQ data, Location, Parameter) and two output screens (Table and Graph). For estimated of health impact attributable to the exposure of air pollution on the target population using AirQ model, that estimate the this impacts to specific air pollutants on a resident population in a certain area and period. The primary and secondary standard of sulfur dioxide according to national ambient air quality standard (NAAQS) 24-hour is 150 µg/m3. Table 1 shows that annual mean of sulfur dioxide in Ahvaz was 157/5 µg/m3 in 2011 which is higher than WHO air quality guidelines and also much higher than NAAQS values. In view of sulfur dioxide concentrations, Mohitzist and Havashenasi were the highest and the lowest stations during this year. The yearly average, summer mean, winter mean and 98 percentile of sulfur dioxide concentrations in these stations has presented in table 1. Sum of total numbers of death attributed to Sulfur dioxide was 194 cases and number of cardiovascular of death in centerline relative risk was 156 cases that 67 percent of them happened when the Sulfur dioxide concentration was less than 90 μg/m3. Relative risk and estimated Attributable Proportion percentage for total numbers of death, cardiovascular of death, respiratory mortality and myocardial infarction were calculated in table 2. Baseline incidence (BI) for this health effect for Sulfur dioxide were 1013, 497, 66, 132 and per 105 so total numbers of death were calculate 194 (RR=1.0040 and AP=1. 7265%), the number of cardiovascular mortality were calculate 156 (RR=1.0080 and AP=3. 3216%), the number of Respiratory mortality were calculate 25 (RR=1.010 and AP=4. 0236%) and the number of myocardial infarction were calculate 33 (RR=1.0064 and AP=2. 8652%) at centerline of relative risk. Also, based on the results of this study, we found that in Ahvaz number of respiratory mortality attributed to Sulfur dioxide were 25 cases and number of myocardial infarction in centerline relative risk was 33 cases that 46 percent of them happened when the Sulfur dioxide concentration was less than 60 μg/m3 in Ahvaz city during 2011. In this study, we estimate total numbers of death, cardiovascular of death, respiratory mortality and myocardial infarction were associated with short and long term fluctuations in concentrations of Sulfur dioxide pollutant in people, using AirQ model in Ahvaz, Iran. In similar work Gudarzi et al In 2009 estimate the Sulfur dioxide hygienic effects in Tehran (capital of Iran). Based on their results, almost 7.82 and 3.6 percent of all cases of whole Respiratory deaths and Hospital Admissions Respiratory Disease are attributed to Sulfur dioxide. In another study Mohamadi et al In 2009 calculated health effects air pollutants in Ahvaz. Based on their results, approximately 4.03 percent of total Respiratory deaths and 1.8 percent Hospital Admissions Respiratory Diseaserelated to Sulfur dioxide. Zalaghi et al In 2010 Survey of health effects of air pollution Ahvaz, Bushehr and Kermanshah. Based on their results, approximately 4.4 percent in Ahvaz, 8.64 percent in Kermanshah and 3.33 percent of total Respiratory deaths attributed to Sulfur dioxide. According to the present research findings and the relieving effects of potential total numbers of death, cardiovascular of death, respiratory mortality and myocardial infarction of Sulfur dioxide exposure on human health in Ahvaz city (located in south-western Iran) during year 2011. Results show that approximately Ahvaz with 5 percent is one of the most polluted cities. The analysis of statistics and comparison of mean and maximum concentration of Sulfur dioxide in four stations in Ahvaz during 24 hrs with air pollution index show that the higher percentage of deaths perhaps could be the result of higher average Sulfur dioxide or because of sustained high concentration days in Ahvaz.