فهرست مطالب samaneh abbasi

Fibroblast Activation Protein (FAP)-targeted nanoparticles (NPs) are designed to accumulate in cancerous stroma. These NPs hold promise for imaging applications in cancer therapy.

This systematic review aimed to comprehensively explore the use of FAP-targeting NPs for cancer diagnosis through different imaging modalities.

This systematic review followed the framework proposed by O’Malley and Arksey. Peer-reviewed studies were searched in the Scopus, Science Direct, PubMed, and Google Scholar databases. Eligible studies were selected, and data were extracted to investigate the FAP-targeting NPs in imaging. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was also utilized to present the results.

Five studies met the specified inclusion criteria and were finally selected for analysis. The extracted data was classified into two categories: general and specific data. The general group indicated that most studies have been conducted in Mexico and have increased since 2022, and the specific group showed that colorectal cancer and Nude mice have received the most research attention. Furthermore, FAP-targeted NPs have demonstrated superior diagnostic imaging capabilities, even compared to specific methods for each cancer type. Also, they have been safe, with no toxicity. 

FAP-targeted NPs using different ligands, such as Fibroblast Activation Protein Inhibitor (FAPI), can accurately detect tumors and metastases, and outperform specific cancer peptides like PSMA in cancer diagnosis. They are also non-toxic and do not cause radiation damage to tissues. Therefore, FAP-targeted NPs have the potential to serve as a viable alternative to FAP-targeted radionuclides for cancer diagnosis.

Research conducted over the years has established that artificial light at night (ALAN), particularly short wavelengths in the blue region (~400–500 nm), can disrupt the circadian rhythm, cause sleep disturbances, and lead to metabolic dysregulation. With the increasing number of people spending considerable amounts of time at home or work staring at digital screens such as smartphones, tablets, and laptops, the negative impacts of blue light are becoming more apparent. While blue wavelengths during the day can enhance attention and reaction times, they are disruptive at night and are associated with a wide range of health problems such as poor sleep quality, mental health problems, and increased risk of some cancers. The growing global concern over the detrimental effects of ALAN on human health is supported by epidemiological and experimental studies, which suggest that exposure to ALAN is associated with disorders like type 2 diabetes, obesity, and increased risk of breast and prostate cancer. Moreover, several studies have reported a connection between ALAN, night-shift work, reduced cognitive performance, and a higher likelihood of human errors. The purpose of this paper is to review the biological impacts of blue light exposure on human cognitive functions and vision quality. Additionally, studies indicating a potential link between exposure to blue light from digital screens and increased risk of breast cancer are also reviewed. However, more research is needed to fully comprehend the relationship between blue light exposure and adverse health effects, such as the risk of breast cancer.

Gliomas, as Central Nervous System (CNS) tumors, are greatly common with 80% of malignancy. Treatment methods for gliomas, such as surgery, radiation therapy, and chemotherapy depend on the grade, size, location, and the patient’s age.
This study aimed to quantify glioma based on the radiomics analysis and classify its grade into High-grade Glioma (HGG) or Low-grade Glioma (LGG) by various machine-learning methods using contrast-enhanced brain Computerized Tomography (CT) scans.
This retrospective study involved acquiring and segmenting data, selecting and extracting features, classifying, analyzing, and evaluating classifiers. The study included a total of 62 patients (31 with LGG and 31 with HGG). The tumors were segmented by an experienced CT-scan technologist with 3D slicer software. A total of 14 shape features, 18 histogram-based features, and 75 texture-based features were computed. The Area Under the Curve (AUC) and Receiver Operating Characteristic Curve (ROC) were used to evaluate and compare classification models.
A total of 13 out of 107 features were selected to differentiate between LGGs and HGGs and to perform various classifier algorithms with different cross-validations. The best classifier algorithm was linear-discriminant with 93.5% accuracy, 96.77% sensitivity, 90.3% specificity, and 0.98% AUC in the differentiation of LGGs and HGGs. 
The proposed method can identify LGG and HGG with 93.5% accuracy, 96.77% sensitivity, 90.3% specificity, and 0.98% AUC, leading to the best treatment for glioma patients by using CT scans based on radiomics analysis.

In the absence of treatment for Severe Acute Respiratory Syndrome Coronavirus 2, there is an urgent need to find alternative methods to control the spread of coronavirus disease 2019 (COVID-19). This study was conducted to compare the effects of vitamin D3 and N-acetylcysteine (NAC) on clinical status indicators in patients with COVID-19 hospitalization in Abadan, Iran.

100 hospitalized patients with COVID-19 infection participated in this study. Patients were randomly allocated to four groups: 3 intervention groups and 1 control group. All patients received standard treatment. In addition, the intervention-1 group received NAC tablets and vitamin D3 placebo ampoules. The intervention-2 group received NAC tablets and vitamin D3 ampoules. The intervention-3 group received vitamin D3 ampoules and NAC placebo tablets. The control group received vitamin D3 placebo ampoules and NAC placebo tablets. Symptoms of the disease and clinical status indicators were compared in groups in the baseline and on days 7, 14, 21, and 28, respectively.

The trial comparison showed that the incidence of cough, dyspnea, and serum glutamic pyruvic transaminase in laboratory tests in the NAC-P1 group was lower than in the other three groups (p <0.005). Also, the results showed a significant difference in the length of hospitalization between the four groups. The length of hospitalization was decreased in the NAC-D3 group (p < 0.024).

Based on the results, vitamin D3 supplements and NAC can improve some outcomes in COVID-19 treatment; however, more randomized controlled trial studies are required in this field.

Health indicators such maternal and child mortality rates are social indicators that are used to measure the development of each country. This study aims to investigate the status of maternal and child health indicators and total fertility rate in the last 10 years in Iran compared to the sustainable development goals (SDG) of the World Health Organization (WHO).

This is a systematic review study. A search was first conducted to find studies related to the study objectives in Iran from 2012 to 2022 in online databases of SID, IranDoc, Web of Science, PubMed, Scopus and Google Scholar, using the keywords: Health, fertility, mothers, children. The results of the studies were compared with the SDG indicators of the WHO.

The initial search yielded 162 articles. After removing duplicates and screening the studies based on the inclusion criteria, finally 20 articles were selected for the review. The status of SDG indicators in Iran, except for neonatal mortality rate and low birth weight, was in accordance with the SDGs of the WHO until 2030.

In the last ten years, the status of most SDG indicators in Iran has been favorable. However, the attention should be paid to the factors affecting neonatal mortality rate and low birth weight to reduce their rates and improve the country’s health status.

Nanoparticles and nanocomposites in low concentrations can be a suitable alternative to antibiotics. In this study, for the first time, silver-zinc oxide nanocomposites were synthesized from the cellulose of Barhi date palm (Phoenix dactylifera L.) seeds.

In this study, the chemical compounds of Berhi date palm seed extract (such as phenols, flavonoids, and ascorbic acid) were first assessed, and silver-zinc oxide nanocomposites were synthesized. The properties of the synthesized nanocomposites were evaluated using different spectroscopy and microscopy techniques. The antibacterial activity of the extract and silver-zinc oxide nanocomposites was investigated against standard strains of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus. The cytotoxicity of the extract and nanocomposites against breast cancer cells MCF-7 and normal cells MCF-10A were finally evaluated.

In the extract, there were high concentrations of flavonoids and phenols. Based on scanning electron microscopy and transmission electron microscopy, the size of synthesized nanocomposites was 20±5 nm with a spherical shape. The diameter of the inhibition zones was 21.3±0.5 mm and 19.4±0.7 mm for Klebsiella pneumoniae and Escherichia coli, respectively. According to the MTT assay results, the nanocomposites were more cytotoxic to MCF-7 breast cancer cells than normal cells MCF-10A.

The synthesized zinc oxide-silver nanocomposites have antibacterial and anticancer properties with fewer side effects and significant efficacy, which can be used as a potential therapy in the future.

Chronic periodontitis is the most common type of periodontitis, which is associated with calculus and plaque accumulation. Several studies have indicated that uncured periodontitis can affect the dental pulp. However, this relationship is controversial. This study aimed to compare histopathological results obtained from the dental pulp in teeth with periodontal problems and healthy teeth.

In this study, 23 teeth with periodontal problems and 23 healthy teeth were extracted. After cutting off 2 mm from the root apex, the teeth were sectioned into apical, middle, and coronal thirds. Then, the specimens were evaluated in both groups based on histopathological features.

According to the evaluations, in the middle third, the amount of inflammation was only statistically significant in the group that consisted of teeth with periodontal problems (P=0.014). There was no significant difference in fibrosis and blood vessel diameter between the two groups. Necrosis in the middle (P=0.002) and coronal thirds (P=0.004) of teeth with periodontal problems was more than the healthy teeth. The lack of odontoblastic integrity in all the sections of teeth with periodontal problems was more than that in healthy teeth (P=0.0001).

Inflammation of the periodontium in chronic periodontitis can lead to histological changes in the pulp, including an increase in inflammation, necrosis, and loss of odontoblastic integrity.

”COVID-19” is a dangerous viral disease that has recently become a pandemic. In the meantime, the knowledge and attitude of medical students in caring for patients are very important.  Therefore, this study was conducted to investigate the knowledge and attitudes of Abadan medical students about the “ COVID-19 “ disease. This cross-sectional study was performed on medical students (n = 255) in 2020-2021 using the convenience sampling method. Data was collected using a personal information questionnaire and a researcher-made questionnaire of knowledge and attitude related to the disease. The total score of students ‘knowledge about “ COVID-19” disease was between 0 and 33, where 0 means minimum knowledge and 33 means between 16 and 80. After confirming the validity and reliability of the questionnaire, the online questionnaire was completed by individuals. The results showed that the mean and standard deviation of knowledge scores and students’ attitudes toward “COVID-19” disease were 13.42 ±2.69 and 22.27 ±3.9, respectively. The results showed that there was no significant relationship between attitude and demographic characteristics. There was a significant relationship between students ‘knowledge score and field of study (P= 0.001) but there was no significant relationship between students’ knowledge score and gender and marital status. Medical students have an acceptable knowledge and attitude toward “COVID-19”. On the other hand, our information about “COVID-19” disease is increasing every day. Therefore, the educational authorities of medical universities should design and implement programs to increase the awareness and attitude of students toward “COVID-19”.

The posterior denture teeth wear faster than the anterior teeth, which can result in occlusal interferences, loss of vertical dimension of occlusion, greater stress accumulation in the anterior region, and higher ridge resorption. This study aimed to compare the wear resistance of three types of artificial acrylic teeth before and after removing the glaze layer.

This in vitro study compared three types of artificial acrylic teeth, namely, Finex (F), SR Orthotyp DCL (S), and Vita Physiodents (V) in six groups (n = 10). Half of the artificial teeth of each brand underwent 0.5‑mm buccal reduction to remove the glaze layer (groups FC, SC, and VC). The teeth were thermocycled and placed in a chewing simulator. The teeth with and without the glaze layer were weighed before and after the wear test. The data were analyzed using ANCOVA (the level of significance was 0.05).

The weight reduction (indicative of wear) was 0.03 ± 0.02 and 0.12 ± 0.03 mg in Groups S and SC, 0.03 ± 0.02 and 0.25 ± 0.04 mg in Groups V and VC, and 0.11 ± 0.15 and 0.28 ± 0.1 mg in groups F and FC, respectively. Removing the glaze layer (P < 0.01), type and brand of acrylic tooth (P < 0.01), and the baseline weight of artificial teeth (P < 0.01) had significant effects on wear resistance of artificial teeth.

The wear of artificial teeth was greater after removing the glaze layer, and the magnitude of wear was also significantly different among the three brands. The group FC showed maximum wear while the groups S and V showed minimum wear.

Approximately 50% of dental amalgam is elemental mercury by weight. Accumulating body of evidence now shows that not only static magnetic fields (SMF) but both ionizing and non-ionizing electromagnetic radiations can increase the rate of mercury release from dental amalgam fillings. Iranian scientists firstly addressed this issue in 2008 but more than 10 years later, it became viral worldwide.

This review was aimed at evaluating available data on the magnitude of the effects of different physical stressors (excluding chewing and brushing) on the release of toxic mercury from dental amalgam fillings and microleakage.

The papers reviewed in this study were searched from PubMed, Google Scholar, and Scopus (up to 1 December 2019). The keywords were identified from our initial research matching them with those existing on the database of Medical Subject Headings (MeSH). The non-English papers and other types of articles were not included in this review.

Our review shows that exposure to static magnetic fields (SMF) such as those generated by MRI, electromagnetic fields (EMF) such as those produced by mobile phones; ionizing electromagnetic radiations such as X-rays and non- Ionizing electromagnetic radiation such as lasers and light cure devices can significantly increase the release of mercury from dental amalgam restorations and/or cause microleakage.

The results of this review show that a wide variety of physical stressors ranging from non-ionizing electromagnetic fields to ionizing radiations can significantly accelerate the release of mercury from amalgam and cause microleakage.

Due to the great importance of maintaining vaccination coverage in children, this study examined the delay in vaccination at birth, 2, 4, and 6 months, which has recently decreased due to the COVID-19 pandemic.

This cross-sectional study was performed on 213 children in 2 groups in Abadan, Iran in 2020. The children who were born from 21 March to 22 September in the years of 2019 and 2020, were divided into groups of 1 and 2. Then based on demographic data, the delay vaccination was compared between two groups, the data was gained from the Sina system and analyzed by chi-square test.

The coverage vaccination decreased during pandemic COVID-19. The percent of no vaccination at birth, 2, 4, and 6 months in 2020 was higher than in 2019, timely vaccination in 2020 was lesser than in 2019 ones. Our data showed that the continuing vaccination depends on the education of parents, age, and weight of the child, but there was no significant association between vaccination and the other demographic variables.

 Regarding high coverage vaccination in Iran, health officer, and health policy maker should attempt to preserve high immunization coverage during pandemic COVID-19, especially in areas with low literature and crowded families.

More than a year has passed since the beginning of the 2019 novel coronavirus diseases (COVID-19) pandemic which has created massive problems globally affecting all aspects of people's life. Due to the emergence of new strains of the SARS-CoV-2, pandemic risk still remains, despite the start of vaccination. Therefore, rapid diagnostic tests are essential to control infection, improve clinical care and stop the spread of the disease. Recently CRISPR-based diagnostic tools have facilitated rapid diagnostic. Here, we review the diagnostic applications of CRISPR-Cas system in COVID-19.

The present study aimed to survey the influence of two different bleaching techniques on changes of color, translucency, and whiteness of the four CAD/CAM materials.

The monolithic blocks of Vita Suprinity, Vita Enamic, IPS e.max CAD, and Katana Zirconia were sectioned to discs with thickness of 2 mm (n=30 / each group). Samples from each type of ceramic were assigned to three subgroups: 1) the 40% hydrogen peroxide for 20 minutes; 2) the 16% carbamide peroxide for three hours/day for 2 weeks; and 3) the control. Then CIELab coordinates of each sample were evaluated before and after the intervention by a spectrophotometer. Final color change (ΔE), Whiteness (ΔWI D), and Translucency Parameter (ΔTP) were calculated. Two-way ANOVA test was adopted to analyze the data (α=0.05).

Type of ceramic, bleaching subgroups, and interaction between them had a statistically significant influence on mean values of ΔE, ΔWID. The influence of bleaching subgroup on the mean value of ΔTP was also significant (P<0.001).

Carbamide peroxide 16% for three hours/day and for two weeks caused the most considerable changes in final color, whiteness, and translucency of the all tested CAD/CAM materials. Maximum color change and whiteness were detected in the Vita Enamic, which were clinically unacceptable.

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.

Luting cement provides the connection between crowns and tooth structure. The sensitivity, solubility, and decomposition stages of the cement after the hardening stage are still subjects of relative controversy. These characteristics could lead to a poor connection between the braces and the teeth, increased probability of decay, and decalcification. The present study aimed to evaluate the adsorption and solubility of 4 types of glass ionomer cement.

Four luting cements were examined. A total of 10 specimens were prepared for each material following the manufacturer’s instructions, and the sorption and solubility were measured in accordance with the ISO 4049’s. Specimens were immersed in artificial saliva for 30 days, and were evaluated for sorption and solubility by first weighting them before incubation (W1), then immersing them in artificial saliva, dehydrating them in an oven for 24 hours, and weighing them again (W2 and W3, respectively). The data were analyzed using SPSS software version 21. One-way analysis of variance (ANOVA) followed by Tukey post hoc test was used to examine the differences among groups (α = 0.05).

As for the both sorption and solubility, there was a significant interaction between the sorption and solubility of all materials (P < 0.001). The sorption values in artificial saliva were highest for glass ionomer cement Riva Luting followed by GC Fuji 1 and Cavex, whereas the least value was observed for Meron (P < 0.000). As for solubility, it was significantly higher in Cavex followed by GC Fuji1 and Meron, but it was significantly lower in Riva Luting.

It was determined that the weight changes of glass ionomer cements significantly varied among all the materials. Riva Luting followed by GC Fuji 1 had the highest water sorption, and the solubility was significantly higher in Cavex followed by GC Fuji1. Meron improved both water sorption and solubility properties among all glass ionomer cements

Although a certain amount of stress is essential, excessive stress can adversely influence the physiological and mental health. Hence, this study aims to assess common stressors and coping strategies among university students.

This qualitative study was conducted from October to November 2019 in Iran. Twelve students were recruited based on purposeful sampling to participate focus group discussions (FGD). Transcripts of three sessions of FGD were analyzed applying Graneheim and Lundman (2004) approach, and a thematic network was applied to illustrate the findings.

The finding emerged 78 codes, 14 subthemes, and 4 main themes. Stressors were classified in two main themes, including individual stressors and the social ones. Behavioral strategies and the cognitive ones were among two categories of coping strategies. According to the thematic network, a full stress student affecting the precious stressors and the social, cultural, and the economic context may manage his/her stress applying the coping strategies.

The findings revealed that university students experienced different kinds of stress, and usually, they do not apply right coping strategies. It is important to establish stress counseling programs for university students. Besides, it is proposing to provide 1st year university students with workshops about the cause of stress and effective coping strategies.

Acrylic resin teeth wear resistance has an important role in the denture longevity. This study aimed to clarify the effect of glaze coating on wear resistance of three types of artificial acrylic teeth.

In this in vitro study, the wear resistance rate of three of acrylic denture teeth (GENIUS, STON and CLASSIC) was compared with Ivoclar teeth (n=25/group). The wear resistance was measured by estimating the weight loss in pre and post removing glaze coating, following 5000 cycles in the chewing simulator device. Data analysis was made using paired t test, one-way ANOVA and Tukey’s post hoc test.

ANOVA test showed that there was no significant difference between the mean amount of wear of GENIUS, CLASSIC, STON and IVOCLAR teeth in the first stage (P <0.061), but this difference was significant (P <0.001) in the second stage. The result of Tukey post hoc test showed that wear rates of GENIUS were significantly lower than other groups (P<0.001). Comparison between the mean wear rates of each dental group at the first and second stages showed a significant difference between average teeth wear resistance of CLASSIC, STON and IVOCLAR in the first and second stages (P <0.001).

In conclusion, the teeth wear resistance of STON and CLASSIC were similar to IVOCLAR. Also, after removing the glaze coating, the teeth wear resistance decreased in all groups but was not statistically significant for group GENIUS.

Oncolytic Herpes simplex virus type 1 (HSV-1) has emerged as a promising strategy for cancer therapy. However, development of novel oncolytic mutants has remained a major challenge owing to low efficiency of conventional genome editing methods. Recently, CRISPR-Cas9 has revolutionized genome editing. In this study, we aimed to evaluate the capability of CRISPR-Cas9 to manipulate the UL39 gene to create oncolytic HSV-1. Herein, three sgRNAs were designed against the UL39 gene and transfected into HEK-293 cell line followed by infection with HSV-1 KOS. After three rounds of plaque purification, several HSV-1 mutants were identified by PCR analysis and sequencing. One of these mutations in which 55 nucleotides were deleted resulted in a frameshift mutation that in turn produced a truncated protein with only 167 amino acids from 1137 amino acids. Functional analysis in Vero and primary fibroblast cells revealed that viral replication was significantly lower and plaque size was smaller in the HSV-1 mutant compared with HSV-1 KOS. Moreover, the relative amount of viral genome present in the supernatants of infected cells (Vero and primary fibroblast cells) with HSV-1 mutant was significantly decreased compared with those of HSV-1 KOS. Our data revealed that targeting UL39 with CRISPR-Cas9 could develop oncolytic HSV-1.

Khajuye Kermani, one of the great poets of the 8th century AH, has composed Gol o Nowruz at the request of a beloved and has dedicated it to his noble patron. According to him, the story is originally in Hindi and has been compiled by Babylonian storytellers. Although it has many similarities to Nizami Ganjavi's Khosrow and Shirin, it is a unique work because of having some love sub-stories, a lot of figures of speech and epics, and mystical and mythological themes. Also, Indian and Babylonian mythological beliefs and traditions are present in Gol o Nowruz and the influence of their culture, beliefs and myths on Iranian mythology, religion and epics and traditions has been proven. With regard to this influence and based on the statements of Khajuye Kermani, in the present article the mythical background of Gol o Nowruz is studied by using descriptive-analytical method, and its relation to the mythical narrative of Indra (Indian god) and waters or the cows captured by the Demon, as well as its relation to the Mesopotamia blessed Goddess and his husband are examined.

Acute respiratory infection (ARI) is caused by human metapneumovirus (HMPV), respiratory syncytial virus type A and B (RSV-A, RSV-B), human parainfluenza viruses 1, 2, and 3 (HPIV-1, HPIV-2, and HPIV-3), influenza viruses A and B (IfV-A, IfV-B), and human coronaviruses (OC43/HKU1, NL63, 229E) worldwide.

This study was conducted to assess the causative agents of viral ARI among hospitalized adults by real-time PCR.

Clinical nasopharyngeal swabs of 112 patients including 55 (49.1%) males and 57 (50.89%) females with ARI were analyzed using multiplex real-time RT-PCR.

Out of 112 specimens, 61 (54.46%) were positive including 10 (8.9%) for influenza H3N2, one (0.89%) for influenza B, 28 (25%) for RSV-A, 18 (16.07%) for HMPV-A, two (1.78%) for HPIV-1, and three (2.67%) for HPIV-3. Two (1.78%) specimens were positive for two agents, RSV-A/HMPV-A and RSV-A/HPIV-3. The distribution of viral infections was 30 among males (26.78%) and 31 (27.67%) among females (P = 0.862). High frequency of RSV-A infection (25%) and the low frequency of influenza B virus infection (0.89%) were detected among patients. The remaining 51 (45.53%) samples were negative for RSV-B, HMPV-B, IfV-A, HPIV2-4A-4B, and HCoVs (OC43/HKU1, NL63, 229E).

The role of other viruses such as human adenoviruses rhinovirus/enterovirus (RV/EV), human bocavirus (HBoV), and human parechovirus (HpeV) was not investigated. Multiplex PCR can be used as a rapid test for the diagnosis of viruses causing acute respiratory infection, which results in decreased length of hospitalization.

This study aimed to compare the optical properties of Zolid FX, Katana UTML, and lithium disilicate laminate veneers.

In this in-vitro experimental study, the maxillary left lateral incisor of a phantom received a laminate veneer preparation. An impression was made, and a die was fabricated using dental stone. The die was scanned using a computer-aided design/computer-aided manufacturing scanner. Ten dies were fabricated from each of the A1, A2, and A3 shades of composite resin. Laminate veneers were fabricated using A1 shade of Katana UTML, Zolid FX, and IPS e.max CAD ceramics (n=10) and placed on composite abutments using bleach and white colors of trial insertion paste (TIP). The optical properties were measured at the incisal, middle, and cervical thirds using a spectrophotometer. Data were analyzed using three-way analysis of variance and Tukey’s test.

The effect of laminate material on the L*, a*, and b* parameters was significant in all areas (P<0.001), except for the L* parameter in the middle and cervical thirds. All color parameters were affected by TIP color in all three regions in most samples (P<0.05). The effect of composite abutment shade was also significant in most cases (P<0.05). The effect of laminate material, abutment shade, and TIP color on the b* parameter was significant (P<0.001). The L* parameter was almost the same in the two zirconia and lithium disilicate ceramic groups.

The composite abutment shade, TIP color, and laminate material should be carefully selected to achieve optimal aesthetics in laminate veneers.

Some studies have shown that loss of teeth and conventional complete dentures have a negative effect on oral health-related quality of life of patients; some other studies have reported high satisfaction with daily life in these patients. Since the results of studies in this regard are contradictory and on the other hand, in Iran only few studies have evaluated this issue, in this study, the quality of life of denture-treated patients was studied in Hamadan Dental School in 2016-2018. Materials &

The participants of this study were selected from patients referring to Hamadan Dental School in 2016-2018. Demographic and clinical data were recorded, and oral health-related quality of life was evaluated by the OHIP-14 standard questionnaire before denture delivery and one month after denture delivery and compared. Data were analyzed with SPSS 21, using descriptive statistics and statistical tests such as t-test, paired t-test, one-way ANOVA and Wilcoxon sign-test (α = 0.05).

The OHIP scores decreased significantly after the delivery of dentures in the all participants (p value = 0.008). This decrease was significant in women, but not significant in men.

In general, the use of complete dentures improved the oral health-related quality of life in the subjects. This improvement is related to aspects such as pronunciation, diet and embarrassment due to the general appearance.

In Iran, over the past 20 years, the prevalence of drug abuse has more than doubled the population growth rate. In order to cope with this problem, psychotherapy approaches have gradually expanded in recent years and an important issue in abandoning addiction is the reason for abandoning addiction. The purpose of this study was to evaluate the effectiveness of sensitization through eye movements and re-processing on cognitive regulation Excitement in addicted patients was to leave in Yasuj.

The study population consisted of all Turkish addicts who referred to addiction treatment centers in Yasuj in 1397. The sample consisted of 30 subjects selected randomly and randomly assigned to two experimental and control groups. Then, a desensitization method was performed on the test group for 5 sessions of 90 minutes and once a week, and no experimental treatment was performed on the control group. The research instrument consisted of Gravinsky's Exponential Crisis Ordering Questionnaire (2006). In order to analyze the data, multivariate covariance analysis (Mancova) and one-variable (Ankawa) and independent t-test and spss software were used.

Multivariate covariance analysis showed that there is a significant difference between the patients in the experimental and control group (p = 0.001) for the sensation of loneliness (42.14 f =), according to the post-test scores of the experimental and control groups in these two variables. The therapeutic method Desensitization through eye movement and re-processing caused cognitive emotion adjustment in addicted patients to leave the experimental group compared to the control group in the post-test phase.
Discussion and

Desensitization through eye movements and re-processing on cognitive emotion regulation in addicted patients were effective in leaving the city of Yasuj. Therefore, psychologists can be trained by teaching this short-term treatment and its implementation on addicted patients, an essential role in increasing Adoption of these people.

The purpose of this study was to determine the relationship between personality dimensions and perfectionism with job stress in sports coaches in Tehran.

The research method was descriptive correlational. The statistical population of this study was all sports coaches in Tehran in the academic year 1398-1989. The sample size of the present study was 278 persons selected by simple random sampling based on Krejcie-Morgan table. Data were collected using Eyseng's personality dimensions (introversion, extraversion), Philip L. Rice (1992), and Hill's Perfectionism (2004). Pearson's correlation coefficient and stepwise regression were used to analyze the data using spss20 software.

The results showed that the correlation coefficients between personality dimensions (introversion, extraversion) and perfectionism with job stress were statistically significant (p <0.05). Also, predictors of job stress in coaches based on personality dimensions (introversion, extraversion) and perfectionism were significant and the predictor variable of personality dimensions (introversion, extraversion) and perfectionism had predictive power of criterion variable (occupational stress).

Personality dimensions (introversion, extroversion) and perfectionism are associated with job stress in coaches except introversion.

The eternal mythological motifs with flexibility and deep extensive meanings, ever exist in the various narratives according to their contents and also to the intellectual and social characteristics of the different periods. They also maintain that beliefs which are the bases of the narratives forming. Volcano is one of these motifs which transfigures as a dragon or a daemon. Struggle of the main character with this daemon is interpreted as his bravery, his competency to achieve the goal and also as a benediction upon the others. This ancient motif which is related to the Aryan mythology, not only exist in the epic narratives, but also it is possible to see its displaced samples in some of the romantic poems. In this essay, the mythological motif of the volcano has been studied in these four romantic poems: Homay-o-Homayoun, Gol-o-Norooz, jamshid-o-khorshid, Mehr-o-Mah. Also, this motif in the romantic poems is compared with its role in the epic narratives. So, the dynamic current of the myths in the non-epic texts will be proved.