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عضویت

فهرست مطالب shahab masoumi

  • Manizheh Mostafa Gharehbaghi, Fakhralsadat Mortazavi, Hanieh Hosseinzadeh-Asl, Iman Bagheri Gahvechi, Razieh Parizad, Samira Jafarisis, Shahab Masoumi *
    Background
    Renal microlithiasis includes renal hyperechogenic deposits in the calyces, pelvis, or ureter with a diameter of less than 2-3 mm by ultrasound. Currently, there is no information about the outcome and possible complications of renal calcification in premature infants in Iran. The current study aimed to evaluate its outcome in preterm infants.
    Methods
    A total of 50 preterm infants with microlithiasis and nephrocalcinosis enrolled in study. The follow-up ultrasound was evaluated 2, 6, and 12 months after diagnosis. Following the diagnosis, infants were assessed for nephrocalcinosis progression. The group was termed unrecovered if the issue persisted during follow-up, and it was considered recovered if it disappeared on follow-up ultrasound. The neonatal data included gestation age, birth weight, length of hospital stay, age at diagnosis of microlithiasis, and used medications.
    Results
    A total of 50 premature infants with microlithiasis and nephrocalcinosis, including 14 females (28%) and 36 males (72%), were born with an average gestation week of 30.78 ± 2.78. The mean age of diagnosis was 2.60 ± 1.11 months. The average hospital stays at the neonatal intensive care unit) NICU (and neonatal ward were 27.38 ± 16.06 and 10.50 ± 9.57 days, respectively. At the end of the 12-month study period, renal calcification recovered in 40 (80%) patients. There was no significant difference between the two groups of patients with sustained and recovered microlithiasis in terms of gender, age of onset of renal calcification, gestational age, mean hospital stay in NICU and neonatal ward, use of antibiotics, potassium citrate, and hydrochlorothiazide. A p-value of less than 0.05 was considered statistically significant for all statistical analyses.
    Conclusion
    The obtained results of the study reveal that a high percentage of premature infants with nephrocalcinosis recovered at the end of the 12-month period, indicating this phenomenon is benign. Keywords: Aminophylline, Kidney function, Microlithiasis, Nephrocalcinosis, Premature infants
    Keywords: Aminophylline, Kidney function, Microlithiasis, Nephrocalcinosis, Premature infants}
  • Shahab Masoumi *, Ahmad Separham, Razieh Parizad, Samira Jafarisis, Marjan Assefi

    Congenital coronary artery anomalies are relatively rare, occurring in approximately 0.6%-1.3% of cases undergoing coronary angiography. Among these anomalies, a unique cardiac abnormality known as a dual left anterior descending artery (LAD) stands out. A dual LAD is characterized by the presence of 2 LADs in the anterior interventricular sulcus. This structural deviation consists of a shorter LAD that terminates high in the anterior interventricular sulcus and a longer LAD that extends to the distal sulcus, supplying blood to the cardiac apex. Percutaneous procedures on dual LADs are even less frequent. We describe a 53-year-old woman with typical burning chest pain, ST-elevation in leads I and aVL, and positive troponin I enzyme. Coronary angiography revealed a thrombotic lesion with 99% stenosis at the proximal part of the LAD. The main LAD originated properly from the left coronary cusp, and the remainder of its course was supplied by a second branch originating from the right coronary cusp. Computed tomography angiography and echocardiography were performed for the LAD course. The patient was discharged after an uneventful 1-week hospital stay.

    Our case is particularly noteworthy for several reasons. Firstly, this dual LAD anomaly is uncommon, and patients with dual LADs less frequently have a ramus artery. Secondly, there have been only a few documented cases of percutaneous transluminal coronary angioplasty performed on short LADs. The key takeaway from this scintillating case study is the significance of identifying the artery responsible for blood supply to the cardiac apex.

    Keywords: Congenital abnormalities, Anomalous left coronary artery, Percutaneous transluminal angioplasty}
  • Mehrnoush Toufan, Naser Khezerlou Aghdam, Shahab Masoumi, Mahshid Dehghan, Aisan Akhgari

    Myxomas are rare cardiac neoplasms and may present as single or multiple tumors. Only a few cases of single biatrial myxomas have been reported. We report a very rare case of this condition in a middle-aged woman, presenting with exertional dyspnea and cough. The patient had a resting tachycardia of 105 beats per minute, and cardiac auscultation discovered a mid-diastolic murmur across the mitral valve, followed by a tumor plop focused on the apex and elevated levels of C-reactive protein (1+) and creatine phosphokinase in lab data. The diagnosis was made via transesophageal and transthoracic echocardiographic examinations, showing the tumor extension through a patent foramen ovale (PFO). The operation was undertaken, the myxoma was excised, and the PFO was repaired. She was discharged with no further complications. Although myxomas are rare, considering this condition before surgery is significant. The involvement of both atria via a PFO is possible.

    Keywords: Myxoma, Cardiac neoplasm, Foramen ovale, patent}
  • Vahideh Toopchizadeh *, Mohammad Barzegar, Shahab Masoumi, Fatemeh Jahanjoo
    Objective
    To compare prevalence of 25-hydroxyvitamin D deficiency in cerebral palsied (CP) with healthy control children and to evaluate possible correlations between 25-hydroxyvitamin D and severity of CP and motor function.
    Materials and Methods
    In this case control study, serum levels of 25-hydroxyvitamin D were evaluated in 65 children with CP and compared with 65 healthy children. Blood samples were taken to measure levels of 25-hydroxyvitamin D, calcium, phosphorus and alkaline phosphatase. Regarding 25-hydroxyvitamin D levels, patients were classified as sufficient (≥30 ng/ml), insufficient (20-30 ng/ml) and deficient (
    Results
    Mean 25-hydroxyvitamin D levels were 28.03±24.2 ng/ml in patients and 30±1.94 ng/ml in control group. 25-hydroxyvitamin D deficiency was seen in 44.6% of CP and 18.5% of healthy children. There was no significant difference in 25-hydroxyvitamin D levels between boys and girls, CP types and use of antiepileptics in case group. There was significant negative correlation between age and 25-hydroxyvitamin D levels. The correlation between 25-hydroxyvitamin D and Gross Motor Function Classification System was not significant.
    Conclusion
    25-hydroxyvitamin D deficiency is common in children with CP in comparison with healthy children. There was significant negative correlation between age and 25-hydroxyvitamin D levels .Routine measurement of 25-hydroxyvitamin D levels and its proper treatment is recommended to prevent its deficiency and subsequent consequences.
    Keywords: Cerebral Palsy, Children, 25-hydroxyvitamin D, Motor function}
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