فهرست مطالب v.vidya lakshmi

Bioresorbable nano stents represent a revolutionary advancement in the field of interventional cardiology, offering a novel approach to address the challenges associated with traditional stent technologies. These innovative devices are designed to provide temporary structural support to blood vessels during the critical healing phase following interventions, such as angioplasty. The key feature of bioresorbable nano stents lies in their ability to gradually degrade over time, aligning with the natural healing processes of the body. Nanotechnology plays a pivotal role in the development of bioresorbable nano stents, allowing for precise control over material properties, degradation kinetics, and biocompatibility. The customization afforded by nanomaterials enables tailoring stent characteristics to match the specific needs of individual patients and diverse clinical scenarios. This level of customization contributes to enhanced safety, reduced risk of complications, and improved patient outcomes. The controlled degradation of bioresorbable nano stents eliminates the long-term presence of foreign materials in the body, potentially mitigating late complications associated with permanent stents, such as in-stent restenosis and thrombosis. This abstract explores the potential benefits of bioresorbable nano stents, including their role in minimizing inflammatory responses and adverse reactions. In addition, the integration of nanotechnology enables the incorporation of imaging agents, antimicrobial coatings, and other functionalities, further expanding the capabilities of these innovative medical devices. The dynamic nature of nanomedicine, coupled with interdisciplinary collaboration, continues to drive advancements in bioresorbable nano stents, positioning them as a transformative technology in the landscape of cardiovascular interventions.

Chemotherapy for cancer frequently uses organometallic compounds containing platinum, such as oxaliplatin, carboplatin, and cisplatin. They are effective against rapidly dividing cancer cells because they form DNA adducts that cause DNA damage and cell death. They work against rapidly dividing cancer cells because of their mechanism of action, which involves the formation of covalent DNA adducts that obstruct DNA replication and transcription. It is true that cisplatin, carboplatin, and oxaliplatin three platinum containing organometallic compounds, are frequently utilized in cancer chemotherapy. These substances belong to a group of medications called platinum-based chemotherapeutics, and they have been used to treat a number of cancer types. Covalent DNA adducts are formed by oxaliplatin, carboplatin, and cisplatin to produce their anticancer effects. These substances contain platinum atoms that attach to purine bases in DNA to create intrastrain and interstream cross-links. These cross-links damage DNA and cause cell death by interfering with transcription and DNA replication. Platinum-containing compounds are extremely cytotoxic, especially to rapidly dividing cancer cells, because they can cause damage to DNA. The discovery and application of organometallic compounds containing platinum mark a critical advancement in the cancer treatment, and these compounds are still essential parts of chemotherapy regimens. Ongoing research endeavors to ascertain novel compounds based on platinum or substitute metals that exhibit enhanced effectiveness and diminished adverse reactions. These substances are well-known for their capacity to cause DNA damage in quickly proliferating cells, which can result in cell cycle arrest and eventual cell death. Although these conventional platinum drugs have demonstrated efficacy in treating a range of cancers, side effects and resistance development are linked to them. The dynamic field of research aims to improve the overall effectiveness and tolerability of chemotherapy by searching for new anticancer agents. New compounds with improved properties will probably continue to surface as our knowledge of cancer biology and drug development methods grows, which will help cancer treatment approaches to evolve.

The consumption of microorganisms proposed to connect metal nanoparticles is in the glow of advertising of modern nanotechnology. Performs as a biodegradable and joyful loom, designed for the assembly of nanoparticles, appreciations to which it is necessary for squat, ecological compatibility, reduced production expenses, the scalability, and stabilization of nanoparticles are compared in bodily and chemical combination. Biologically connected metal nanoparticles are almost all well-organized miniaturized, usable resources constructed and designed to perform precise functions in the company of enormous prospects. Microbes include this amazing competence towards appearance, such delicate nanostructures. This studies the exercise information of organic combination of zinc oxide and lead nitrate nanoparticles as a result of microbes. Microorganisms engage in recreation directly or indirectly in more than a few biological behaviors because metals present in soil are in constant relation to biological components. In the current study, the reported microbiological combination of nanomaterials uses organic ingredients, primarily prokaryotes and eukaryotes, such as bacteria and fungi (Escherichia coli and Aspergillusniger). Bacterial and fungal cell buildup is questioned among two different chemical salts (ZnO and Pb (NO3)2) together with metal nanoparticles should be effectively synthesized.