فهرست مطالب vijay kumar

In this paper, we define strong deferred summability and deferred statistical summability in intuitionistic fuzzy \(n\)-normed linear spaces (briefly called IF-\(n\)-NLS) and study some of their properties. We also define deferred statistical Cauchy sequence deferred statistical completeness and characterize deferred statistical summability in such spaces. Finally, we will compare deferred statistical summability for different pairs of sequences $\alpha(\ell)$, $\gamma(\ell)$,$u(\ell)$ and $v(\ell)$ satisfying $\alpha(\ell) \leq u(\ell) < v(\ell) \leq \gamma(\ell)$.

Telomeres consist of repetitive G-rich nucleotides located at the end of each chromosome, acting as protein binding sites. The aim of this study was to examine the differences in telomere length in blood, saliva, and tissue samples at various stages of oral precancerous and cancerous lesions.

Samples of blood, tissue, and saliva were collected from patients with oral precancerous and cancerous lesions. DNA extraction was performed. Then, a TRAP assay was conducted to assess and compare the telomere length and telomerase expression.

The levels of telomerase activity (TA) in the DNA samples ranged from 0.19 to 6.91 (2.05+1.37) among oral squamous cell carcinoma (OSCC) patients and from 0.17 to 4.5 (0.28+4.25) among precancerous patients. A significant difference was observed in TA levels between OSCC and precancerous samples (t=3.9691, P= 0.0000).

Assessing the telomerase activity is crucial for studying the behavior of carcinoma in the clinical setting. The augmented telomerase expression and the length of telomere contribute to OSCC progression. Hence, this study adds a diagnostic tool that can serve as a biomarker for the early detection and prognosis of OSCC.

Literacy in oral health is essential for promoting and preventing oral health issues. Evaluating oral health literacy enables the identification of opportunities to implement interventions at both policy and practice levels, aiming to improve oral health outcomes for individuals and populations. This review aims to conduct a systematic review focused on the association between oral health literacy and oral conditions. 

The search strategy aimed to retrieve both published and unpublished literature. The databases searched include PubMed, Scopus, Google Scholar, Web of Science, CINAHL, ProQuest, EBSCO- APA PsycInfo, and Shodhganga. After the search, all retrieved citations were examined to determine whether they meet the inclusion requirements. When possible, quantitative data was combined and analysed through a meta-analysis. The methodological validity of the included studies was critically evaluated using the JBI critical evaluation tool. The effect size was provided as a risk ratio or odds ratio for dichotomous data, while standard mean differences was used to depict it for continuous data. Statistics were used to evaluate study heterogeneity. In cases where statistical pooling is not possible, the findings were reported descriptively.

This review incorporated data from 9,044 participants across 22 cross-sectional studies. The results indicated an association between inadequate oral health literacy and  individuals experiencing dental caries [OR: 0.36(95% CI 0.15,0.89) Thirteen studies, 4857 participants], Periodontal pocket [OR: 0.38 (95% CI 0.24, 0.62) five studies, 2651 participants], and tooth loss [OR: 0.57(95% CI 0.45,0.72) 2 studies, 1281 participants]. However, it's important to note that the studies included in this review were identified as having a high risk of methodological bias. 

Oral health Literacy is associated with poor oral health conditions; however, the quality of evidence is low.

This paper aims to provide a comprehensive examination of the Brain-Computer Interface and the more scientific discoveries that have resulted from it. The ultimate goal of this review is to provide extensive research in BCI systems while also focusing on artifact removal techniques or methods that have recently been used in BCI and important aspects of BCIs. In its pre-processing, artifact removal methodologies were critical. Furthermore, the review emphasizes the applicability, practical challenges, and outcomes associated with BCI advancements. This has the potential to accelerate future progress in this field. This critical evaluation examines the current state of BCI technology as well as recent advancements. It also identifies various BCI technology application areas. This detailed study shows that, while progress is being made, significant challenges remain for user advancement A comparison of EEG artifact removal methods in BCI was done, and their usefulness in real-world EEG-BCI applications was talked about. Some directions and suggestions for future research in this area were also made based on the results of the review and the existing artifact removal methods.

The world is worsely hit by the COVID‑19 pandemic resulting in increased morbidity and mortality. Increased mortality has been observed in older adults with multiple comorbidities. Six‑minute walk distance (6MWD) at admission can help us to guide the requirement of oxygen during hospital stay that can be used to determine which patient can be managed at home.

This study was a prospective observational study conducted on COVID‑19 patients admitted at AIIMS, New Delhi, from October to December 2020. Patients aged more than 60 years were included in the study and underwent 6‑min walk tests. Polypharmacy and multimorbidity were also assessed along with dyspnea which was measured on BORG scale. P < 0.05 was considered statistically significant. Statistical software STATA (version 14.2) was used for all the analyses.

The mean age of the study population was 68.76 (7.4). Oxygen saturation prior to the 6‑MWT was normal and has significantly higher than the post test (P ≤ 0.001). 6MWD was significantly correlated with pre values of oxygen saturation. 6MWD was observed more in patients who did not require oxygen during hospital stay. Self‑reported dyspnea, pulse rate, oxygen saturation, and systolic blood pressure were significantly associated with the patients who had an oxygen requirement during the hospital stay.

Self‑reported dyspnea after 6MWT was found to be associated with oxygen requirement during hospital stay. Patients who have covered more distance in 6‑min walk test have less oxygen requirement during hospital stay hence can be managed at home. This will reduce the health‑care burden and will help to tackle the outburst during the ongoing pandemic.

In this paper our main goal is to study the climatology and variability of the frequency of thunderstorm days over Bangladesh region throughout the year. It has been found that the mean thunderstorm days increase significantly from March to May, i.e. during the pre-monsoon season, although the graphical devices show that there does not seem to be much deviation from the occurrences of thunderstorms each year. The mean monthly and seasonal thunderstorm days were maximum in 1993, followed by that in 1997; whereas it was a minimum in the year 1980, with an extension in its frequency in the subsequent years 1981 and 1982. The coefficient of variation of both annual and seasonal thunderstorm days is minimum over the areas of maximum frequency of mean thunderstorm days and vice-versa. The time-domain analysis confirms that the occurrence happened to be maximum in the year 1991, although each and every state did not witness thunderstorms every year. Also some other time-domain models like autocorrelation and seasonal integrated moving average provide adequate evidence for exploring the number of thunderstorms which happen to confirm the trend of occurrence of thunderstorm over the years.

Parthenium hysterophorus (Asteraceae) is known as one of the most troublesome weeds, causing severe environmental, economic, human and animal health problems in India and around the world. During a series of surveys for natural enemies of P. hysterophorus, a leaf blight pathogen was isolated from the affected parts of the Parthenium following the standard isolation techniques using potato dextrose agar (PDA) media. Koch’s postulates were performed and found satisfactory for the isolate and proved to be pathogenic to this weed. On the basis of cultural, morphological and molecular characteristics, the pathogen was identified as Alternaria macrospora MKP1. The pathogen was studied for various histopathological parameters and the results showed that this pathogen has a good potential to control Parthenium weed.

Oxford medial unicompartmental knee replacement (UKR) is indicated in patients with anteromedial osteoarthritis (AMOA) of the knee. Microplasty (MP) instrumentation was introduced in 2012 as an improvement over phase 3 instrumentation. Advantages of this instrumentation include conservative tibial cut, decreased tibial re-cut rate and improved component alignment. We report the results of UKR with the new instrumentation in a consecutive series with a minimum follow-up of 2 years.
A prospective study of 115 cemented medial Oxford UKRs implanted in 89 patients was done. Postoperative alignment of the tibial and femoral components was analysed. Patient reported outcome measures were recorded using Oxford Knee Score (OKS) and the American Knee Society Score (KSS). Tegner Activity Scale (TAS) was used to record the activity level.
115 consecutive medial Oxford UKRs were studied. All patients were followed up annually in this prospective ethically approved study. The mean follow-up was 36 months and the minimum follow-up was 25 months. No patient died and none were lost to follow-up. At the final follow-up, the average OKS of the cohort was 39.5 (SD: 5.7). 91.2 % of the patients had good or excellent OKS with only 3.5 % reporting poor OKS. The overall limb alignment was 4.80 varus (0 – 140 varus). Tibia was recut in 5.2 % of cases. Median bearing size was 3 (range: 3 to 6). There was one case of bearing dislocation and one case of aseptic tibial loosening.
This is the first study to report results of MP instrumentation at a minimum follow-up of 2 years. Our study indicates that the new instrumentation results in reliable and accurate implantation of femoral and tibial components in majority of the cases, with a decrease in number of alignment outliers, and also a reduced rate of bearing dislocation.

Ion conducting gel polymer electrolytes based on poly acrylonitrle (PAN) complexed with different weight percent ratios of Sodium Fluoride (NaF) salt were prepared by using solution cast technique. Structural characterization was performed using X-ray diffraction (XRD) technique and Fourier transforms infrared (FTIR) spectroscope technique. From the X-rd results increase in amorphous phase with the increase of dopant salt concentration was observed. Fourier transform infrared (FTIR) spectroscopic analysis confirmed the complexation of the salt with the polymer matrix. Electrical conductivity was measured that the magnitude of ionic conductivity increased with the increase in the salt concentration as well as temperature. The surface morphology was observed by using Scanning Electron Microscope (SEM), the optical band gap measured from UV-Vis Spectroscopy. The sample containing 30 wt% of NaF exhibited the highest conductivity of 1.82x10-4 S cm-1 at 303K and 2.96x10-3 S cm-1 at 373K. The temperature dependence of ionic conductivity of these films followed Arrhenius relation. Transference number measurements were carried out to investigate the nature of the charge transport species in the polymer electrolyte systems. The transference number data showed that the charge transports in these systems are predominantly due to ions. Using these polymer electrolyte films, electrochemical cells were fabricated and their discharge characteristics were studied. Various cell parameters, such as open circuit voltage, short circuit current, power density and energy density were determined.

The issue of a possible malignant transformation in the lesions like epithelial dysplasia and oral lichen planus (OLP) is a matter of serious controversy. The purpose of this study was to suggest the malignant transformation rate in OLP and oral epithelial dysplasia (OED) by using immunohistochemical expression of the tumor markers Ki-67, p53, BCL-2, and BAX.This was a cross-sectional study carried out among 70 samples, including 10 samples from normal healthy mucosa categorized into Group 1, Group 2 (30 OLP), and Group 3 (30 OED) samples. Five sections (4 μm thick) were obtained and stained with monoclonal antibodies such as Ki-67, p53, BCL-2, and BAX and analyzed for number of positive cells and also for intensity of staining. Statistical analysis was done using Mann-Whitney U-test (P < 0.05). Significant results were found only for expressions of Ki-67, p53, BCL-2 markers in both study groups (P < 0.05). In these groups, the intensity of staining was mostly mild to moderate for all studied tumor markers. In this study, subjects with an average positive IHC expression of Ki-67, p53, BCL-2, and BAX markers in normal mucosa was about 22.5%, which was significantly lower when compared with OLP (54.9%) and OED (64.9%). The high propensity for malignant transformation in OED followed by OLP suggests that a wide range of inherent and extrinsic factors contribute to the disease progression and malignant transformation.

Nitrogen containing bisphosphonate (N-BP) therapy is used extensively to treat osteoporosis and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially within those patients who are receiving either long-term N-BP therapy alone and/or associated with invasive dental procedure. Bisphosphonates accumulate almost exclusively in maxillofacial skeleton owing to high bone turn over remodeling to maintain the mechanical competence. The pathogenesis and why it commonly appears in maxillofacial skeleton and the fixed treatment strategies remains unknown. The aim of this study was to improve the clinician understanding of N-BPs associated osteonecrosis of maxillofacial skeleton by reviewing the past 10 year literature.

For any lacunary sequence $theta = (k_{r})$, we define the concepts of $S_{theta}-$limit point and $S_{theta}-$cluster point of a sequence of fuzzy numbers $X = (X_{k})$. We introduce the new sets $Lambda^{F}_{S_{theta}}(X)$, $Gamma^{F}_{S_{theta}}(X)$ and prove some inclusion relaions between these and the sets $Lambda^{F}_{S}(X)$, $Gamma^{F}_{S}(X)$ introduced in ~cite{Ayt:Slpsfn} by Aytar [S. Aytar, Statistical limit points of sequences of fuzzy numbers, Inform. Sci. 165 (2004) 129-138]. Later, we find restriction on the lacunary sequence $theta = (k_{r})$ for which the sets $Lambda^{F}_{S_{theta}}(X)$ and $Gamma^{F}_{S_{theta}}(X)$ respectively coincides with the sets $Lambda^{F}_{S}(X)$ and $Gamma^{F}_{S}(X)$.

Uttarakhand region is less explored, but possess a great biodiversity. This diversity can be explored for isolation and characterization of new actinomycetes strains for seeking antimicrobial molecules. It can therefore be predicted that novel bioactive metabolite producing actinomycetes can be discovered to combat multidrug resistant bacterial pathogens. Variations in the viable count of actinomycetes were accessed in different altitudes. Actinomycetes were isolated, indentified and screened for their antibacterial activity. The highest viable counts of actinomycetes were recorded in valleys followed by mid hills and high hills. A total of 512 actinomycetes were isolated which were found to belong the 14 different genera of actinomycetes. Mainly the genus Streptomyces was dominant in all the soil samples. Out of 512 isolates recovered, 23.44% exhibited antibacterial activity against one or more tested bacterial pathogens. Of these 56.67% showed activity against Gram-positive bacteria, 26.67% against Gram-negative bacteria while 16.67% showed broad spectrum activity. Isolate DV1S and GR9a-5 showed highest antibacterial properties against several multi-drug resistant bacterial pathogens and were identified using polyphasic approach. DV1S and GR9a-5 were found to be most closely related with S. massasporeus NBRC 12796T and Nocardia nova JCM 6044T respectively. The results of this study strongly support the idea that the viable count of actinomycetes varied greatly with altitude. The actinomycetes species isolated from valleys, mid hills and high hills possess significant capacity to produce compounds which are active against several drug resistant bacterial pathogens.

Nonfunctional adrenocortical carcinoma is an extremely rare malignant tumor in children. Unlike the functional tumor which is detected early due to its hormonal presentation, nonfunctional tumor is detected at a later stage. Here we report a case of a 10 year old girl who presented with abdominal mass and symptoms of short duration. No hypertension and cushingoid features were seen. Serum alpha-fetoprotein, urine vanillyl mandelic acid and homovanillic acid levels were not elevated. CT scan showed multiple pulmonary nodules suggestive of metastatic deposits. With gross and light microscopic findings differential diagnoses of hepatoblastoma, paraganglioma, renal cell carcinoma, adrenal cortical and medullary tumours were made. An array of immunohistochemical markers was done and the final diagnosis given was nonfunctional adrenocortical carcinoma with foci of osseous metaplasia.

Brainstem hemorrhage was first described by Cheyne in 1812 in a pathological study of patients presenting with lethargy and coma. In 1877 Bode reviewed the findings of 67 patients reported in the literature (1). In the United States, the incidence of closed head injury is estimated to be approximately 200 cases per 100,000 persons per year. The financial burden of head injuries in the United States is estimated to be $75-100 billion annually (4). This cross-sectional study, the brainstem was studied by both gross and histopathological examinations. During a period between between July 1, 2010 and June 31, 2011, a total of 71 head injury cases were autopsied and brainstem hemorrhage was seen in 28 of them. Out of the 28 cases, most of the hemorrhages occurred in the midbrain (68%) and least in medulla oblongata (11%), while four cases had pontomedullary junction tearing and one of them presented presented cervicomedullary junction tearing. Hemorrhages are usually the only evidence of injury to the brain-stem in those dying immediately or within a few hours. Failure to realize this has led to underestimation of the frequency of brain-stem hemorrhage after injury, and, indeed, to the frequency of brain-stem lesions of all kinds.