فهرست مطالب yadolah edalatpanah

The use of medicinal herbs in the treatment of diseases has become increasingly widespread, in this regard the Verbena officinalis is considered as one of the herbs that affects pregnancy. The present study was conducted to investigate the Verbena officinalis herb on the level of sex hormones of NMRI female rats during pregnancy. This is an experimental study which divided 40 rats into 5 groups of 8 each and the groups included control, sham, and experimental with 5, 10, and 15 mM alcoholic extract of Verbena officinalis. The serum levels measurement of FSH and LH hormones was done using ELISA (Biotech) method. After blood sampling, the ovaries were stained with hematoxylin eosin for histological examination. Cell count and thickness measurement of different ovarian cells, primitive follicles, primary follicles, growing follicles, graph follicles, lymph nodes, blood vessels, atretic follicles, and abnormal follicles (1 or 2 oocytes in one follicle) were examined microscopically in 6 segments of tissue segments from different groups. The statistical analysis was performed using SPSS23 software.The findings of the present study showed that the consumption of alcoholic extract of Verbena officinalis significantly reduced the levels of LH, FSH, the number of abnormal follicles, the number of graph follicles, and the number of corpus luteum in the experimental group compared to the control group (p≤0.05), the number of primary follicles, the number of growing follicles, the number of ethereal follicles, and the number of blood vessels in the experimental group compared to the control group (p≤0.05). The weight, ovarian weight, ovarian diameter, secondary follicle diameter, and primary follicle diameter decreased in experimental groups compared to control group and sham group; however, this decrease was not significant and abnormal follicle diameter in experimental groups compared to control group and group. Sham increased but this increase was not significant (p> 0.05). The results of the present study show that consumption of Verbena officinalis medicinal plant can be effective in abortion

Diabetes is one of the common metabolic disorders whose complications have many health problems for society. This study has been carried out with the aim of investigating the effects of hydroalcoholic extract of cedar (Ziziphus spina-christi)on blood glucose, urea, and total cholesterol in the Wistar race of diabetic rats. Forty rats in the weighting range of 300 to 350 were selected as sample and were classified into four groups: control, control of cedar, diabetic, and diabetic of cedar and after bloodletting from rats, data were analyzed by SPSS23 software. Results showed that at the significance level of p < 0.05, consumption the hydroalcoholic extract of cedar leaf can be effective in reducing blood glucose, urea and total cholesterol. After four weeks with consumption of cedar, blood glucose in the diabetic group reduced from 214 mg.dl-1 to 174 mg.dl-1. After four weeks with consumption of cedar extract, blood urea in the diabetic group reduced from 9.4 mg.dl-1 to 5.3 mg.dl-1. After four weeks with consumption of cedar extract, the total cholesterol in the diabetic reduced from 66.3 mg.dl-1 to 60.5 mg/dl. The results of this research indicate the effects of the cedar leaf extract on blood glucose, urea, and total cholesterol.

Medicinal plants can be effective in treating diseases due to having various antifungal compounds. The aim of this study was to evaluate the antifungal effects of Prangos ferulace and Plantago majorL against fluconazole-resistant Candida albicans in extracorporeal conditions.

This study was experimental. Prangos ferulace and Plantago majorL plants were prepared from stores in Yasuj, Iran, in the spring and then scientifically approved by the Zardband Pharmaceutical Company in Yasuj. The extract was extracted after sending the plants to the Research Center for Medicinal Plants of Yasuj University of Medical Sciences. In order to prepare the aqueous extract of the plants, 3 g of plant powder was added to 30 ml of distilled water and placed on a shaker (Behdad, Tehran, Iran) for 24 h. The strain used in the present study was Candida albicans ATCC 10231, which was prepared by Shiraz University of Medical Sciences, Shiraz, Iran. In the present study, the alcoholic extracts of Prangos ferulace and Plantago major L were used at the concentrations of 7.5, 15, and 30 mg/ml. The non-growth halo diameter (in millimeters) was measured using the standard paper disc diffusion method. The minimum inhibitory concentrations (MICs) required to inhibit the growth of 90% and 50% of organisms were also evaluated. Finally, the number of living cells was counted, and the data were analyzed using ANOVA test in SPSS software (version 23).

The results showed that at a concentration of 30 mg/ml, the maximum diameters of the non-growth halo were 15.3 mm for Prangos ferulace and 12.4 mm for Plantago major L. Regarding the MIC value, the MIC50 and MIC90 were respectively obtained as 19 and 38 μg/ml for Prangos ferulace and 14 and 29 μg/ml for Plantago major L (p < 0.05). Considering the live cell count, the lowest number of live cells was formed at a dilution of 10. The mean value of this variable was obtained as 7.3 and 4.2 CFU/ml for Prangos ferulace and Plantago major, respectively.

Prangos ferulace and Plantago major L. prevented the activity of Candida albicans due to their effective medicinal compounds.

Due to the increasing number of premature births in recent years, high mortality rate of premature infants, and high risk of future disability of these children, it is necessary to obtain information on preterm labors and ways to diagnose premature neonates. This study aimed to compare the selected blood characteristics of women with term and preterm labors referring to the maternity ward of Imam Khomeini Hospital in Dehdasht, Iran.

This cross-sectional was conducted on 110 women referred to the maternity ward of Imam Khomeini Hospital in Dehdasht, Iran, during 2019. The participants were divided into two groups of the term (n=80) and preterm (n=30) labors. Simple random sampling was performed, and after obtaining the informed consent, blood iron, blood platelet, body mass index (BMI), white and red blood cell count, ferritin, and total iron-binding capacity (TIBC) were examined in this study. The data were analyzed in SPSS software through an independent t-test.

The results showed that the mean blood iron, blood platelet, BMI, white blood cells, ferritin, and TIBC were higher in women with term labor, compared to those with preterm delivery (p < 0.05). Moreover, there were no significant differences between the two groups regarding the mean red blood cell count (P> 0.05).

Considering the necessity and importance of improving the level of healthy fertility, significance of maternal and infant health index as national health indicators, prevalence of some blood factor deficiency and its complications, and importance of normal BMI in the course of pregnancy and low-risk delivery, it is critical to pay attention to these factors to reduce preterm labors.

Honey acts as a powerful and effective dietary compound against many diseases. This study aimed to investigate the effect of different kinds of honey native to grasslands of Kohgiluyeh and Boyer-Ahmad Province, Iran, on the activity of Candida albicans.

This laboratory study was performed in 2019. To evaluate the antimicrobial activity,  seven kinds of honey were obtained from Kohgiluyeh and Boyer-Ahmad Province, Iran. Furthermore, they were investigated with Fluconazole against Candida albicans using the measurement of the zone of inhibition diameter, minimum inhibitory concentration (MIC), and live count. Following that, Oak and Forty tropical plant (i.e., Chelgiah) honey were identified to contain the highest antimicrobial activity in the culture medium. Subsequently, 48 laboratory animals were divided into 4 groups (12 animals per group). The first 2 groups were candida-infected animals treated with two natural kinds of honey (Oak and Forty tropical plants). Moreover, group 3 was regarded as a drug control and treated with standard Fluconazole, and the fourth group was a positive control that was under no treatments after being infected with digestive candidiasis. Data were analyzed in SPSS software (version 21) using one-way ANOVA and paired t-test.

The results of measurement of the zone of inhibition diameter and MIC showed that at the concentrations of 40% and 50%, Oak and Forty tropical plant honey had the most significant effects on Candida albicans (P

Diabetes mellitus can occur due to insulin deficiency or environmental tissues resistance to insulin with the reduction of insulin secretion. The present study aimed to investigate the therapeutic effect of amniotic mesenchymal stem cell transplantation in the treatment of type 1 diabetes.  This study was of experimental type and the animals were divided into four groups including the control or healthy, the diabetic control group, the group receiving cells with the medium, and the group receiving only supernatant soup. Glucose and blood insulin levels and animal weight were studied by ANOVA and t-test during the study. With the first stage of stem cell transplantation, a significant reduction was found in the animal blood glucose of both groups receiving cell and medium (p = 0.004) and the group receiving supernatant soup (p = 0.014) than the control group. Such results were not observed after the second stage. The insulin levels had no statistically significant difference. The present study indicated that the repeated transplantation of Amniotic Mesenchymal stem cells can decrease the blood glucose but increase the blood insulin level and the injection of supernatant soup alone be solely effective as much as the cell transplantation.

Abstract Diabetes mellitus is a common metabolic disorder, with complications caused by many health problems in society. Reducing blood glucose levels in diabetic patients with medicinal herbs is of great clinical importance. This study was performed to investigate the effects of Cedar Butanlite Extract on insulin-induced hypoglycemia in Streptozotocin Wistar male diabetic rats. In this study, 40 Wistar rats with a weight range of 250-300 gr were selected and divided into 5 groups. Blood glucose levels were measured by glucose oxidase assay. Data were analyzed by SPSS-24 software and t-test. Charts were prepared using Excel software. The results showed that the mean glucose level of diabetic rats treated with insulin and alcoholic extract of cedar showed a significant decrease compared to insulin treatment and cedar treatment (P