yoones sadabadi

The anatomy of the great palatine canal is important for dentists and maxillofacial surgeons in terms of performing various surgical procedures such as local anesthesia, dental implant placement, and paranasal sinus surgery. In the axial view, the great palatal foramen (GPF) is usually seen in the alignment of the second molar and is hidden by the thick mucosa, which is important to determine its clinical position according to the anatomical signs. The present study aimed to investigate and evaluate the anatomical variations of the large palatine foramen and canal, the large and small palatine foramen, and the location of the large palatine foramen by CBCT technique.

In this retrospective cross-sectional study, 316 CBCT images related to the maxilla were analyzed to identify the large and small palatal foramen and the palatal canal and their positions. In this cross-sectional study, CBCT images obtained from patients were evaluated in terms of morphology and diameter of the large palatal foramen and large palatal canal. The anatomical shape of the large palatal canal in the sagittal plane and the position of the large palatal foramen in the axial plane relative to the second molar tooth in the upper jaw were investigated. The required information was collected in the checklist prepared for this purpose. With the help of two observers specializing in maxillofacial radiology, the CBCT images were examined and gave their opinion, and 20% of the data were repeated for the observer's error. In this study, the samples were divided into three age groups for statistical analysis. The relationship between age groups, GPF, and large palatal canal was investigated. After collecting the data and information, it was analyzed by SPSS V.23 software, and the data was described using number and percentage indicators and central and dispersion indicators. The significance level was considered to be P<0.05.

Results showed that large palatal holes are seen in 63.9% of the distal second molar and 36.1% flush with the second molar in CBCT images. In terms of foramen morphology, the most common shape was oval in 107 patients (33.9%). Also, according to the surveys, the most common morphology of the large palatal canal was cascade in 120 people (38%). Additionally, the results showed that there is a significant relationship between the morphology of the large palatal foramen and gender, so that the round and oval shapes are more common in men, and the round, split, and teardrop shapes are more common in women. The number of small palatal foramen was less than 3 in 88.8% of cases. According to statistical tests, there is a significant relationship between the diameter of the small palatal foramen with sex, age, and jaw direction (P=0.046).

Considering that the large palatal foramen is located in the distal second molar in most cases a significant relationship was found between the shape of the GPF and its position. Therefore,  to avoid surgical problems, it is necessary to evaluate the anatomical variations of the hole and the large palatal canal, especially before the maxillary wisdom tooth surgery.

The acidic component of liquid medicinal syrups used by pediatric patients may cause erosion and partial demineralization. This study aimed to evaluate the effect of cheese and casein phosphopeptide‑amorphous calcium phosphate (CPP‑ACP) on erosive lesions of primary teeth enamel following exposure to amoxicillin and ibuprofen syrups.

In this in vitro study, 60 noncarious deciduous molars were used. After measuring the surface microhardness of the samples, they were randomly separated into two groups and immersed in either amoxicillin or ibuprofen for 1 min three times per day. CPP‑ACP, cheese, and artificial saliva were then applied to each of the three subgroups (n = 10). After each immersion time, 10 min of therapy was given. Between treatment intervals, the samples were kept in artificial saliva. The microhardness was remeasured after 1 week. Data were analyzed using SPSS software through repeated‑measures ANOVA (α = 0.05).

All samples’ microhardness reduced considerably after immersion in liquid pharmaceuticals(amoxicillin [84.9 kgf/mm2 ] and ibuprofen [75.1 kgf/mm2 ]), but increased significantly following exposure to therapeutic solutions. There was no difference between the amoxicillin‑cheese and amoxicillin‑CPP‑ACP subgroups (P = 0.975). A statistically insignificant difference was found between the ibuprofen group and the ibuprofen‑CPP‑ACP subgroup (P = 0.499).

As a result, cheese and CPP‑ACP can be utilized to remineralize erosive lesions caused by amoxicillin or ibuprofen exposure.

The purpose of this in vitro study is to ascertain how NovaMin and Er,Cr:YSGG laser radiation affect the remineralization of primary tooth enamel lesions.

40 main teeth served as the study’s sample size. These teeth were allocated into five groups at random. The first group served as a negative control (artificial saliva); the second group served as a positive control (APF gel 1.23%); the third group NovaMin, the fourth group Er,Cr:YSGGlaser, the fifth group Er,Cr:YSGG laser and finally, the application of NovaMin. For the purpose of measuring microhardness, all samples were submitted to the dental materials laboratory three times.

The collected data were compared using the SPSS 28 program between the baseline measurement, after demineralization, and after remineralization. The data were analyzed using ANCOVA and Bonferroni tests. All groups demonstrated a considerable increase in microhardness as compared to the negative control group (P < 0.05). With the exception of the third and fourth groups, there was no discernible difference in the rise in microhardness between the other groups. The third and fourth groups were compared, and the results revealed that NovaMin had a greater impact than laser therapy alone (P = 0.023). Scanning electron microscopy (SEM) analysis backed up the findings.

In comparison to using the Er,Cr:YSGG laser alone, using NovaMin alone can speed up the remineralization of erosion lesions on the surface of primary teeth.