فهرست مطالب yueqin chen

 Early differential diagnosis of coronavirus disease 2019 (COVID-19) and Mycoplasma Pneumonia (MP) are hampered by non-specific symptoms, the lack of rapid responding laboratory measures and the presence of family aggregation. Chest computed tomography (CT) plays a significant role to detect the distribution, density and morphology of lesions caused by either COVID-19 or MP.

 To compare the symptoms, laboratory parameters, and chest CT results of adults with COVID-19 and MP and to assess the use of these findings in the differential diagnosis of these diseases.

 The initial clinical manifestations, laboratory results, and chest CT findings of 45 adult patients with COVID-19 (COVID-19 group) and 55 adult patients with MP (MP group) were reviewed retrospectively. All of the patients were diagnosed in the public hospitals in the epidemic area from 20 January to 28 February 2020.

 Muscle ache and fatigue were more frequently present in the COVID-19 group (P = 0.009 and 0.029, respectively). Increased procalcitonin levels were more common in the MP group (P = 0.001). The chest CT results indicated that bilateral lung involvement, ground glass opacities, “crazy-paving” patterns, and air bronchogram signs were more common in the COVID-19 group (P < 0.001 for all), respectively. However, single lobe involvement, pulmonary consolidations, lobular central nodules, generalized bronchial wall thickening with luminal stenosis, and bronchial mucus impaction were more common in the MP group (P < 0.001 for all). Receiver operating characteristic analysis of a model established using CT parameters indicated a good or excellent performance in distinguishing COVID-19 from MP.

 COVID-19 and MP have similar clinical manifestations and laboratory results in early stage. However, the chest CT findings are valuable in the differential diagnosis of these two diseases, particularly in patients from COVID-19 epidemic areas.

 Chest computed tomography (CT) is a recommended screening and assessment tool for patients with suspected coronavirus disease (COVID-19). However, CT units are currently not available in many temporary hospitals and centralized isolation places.

 To delineate the workflow of mobile CT unit and evaluate its role in screening for COVID-19 infection in temporary hospitals and centralized isolation locations.

 Two hundred and twenty-three patients under medical observation in temporary centralized isolation were enrolled in this study. All patients underwent reverse-transcription polymerase chain reaction (RT-PCR) testing and mobile CT chest examinations. Communication, storage, and browsing of CT data were performed with 4G and cloud technology. Image quality and radiation dose were evaluated and compared with a commercial conventional 64-row CT scanner. Additionally, the sensitivity of initial chest CT and the initial RT-PCR for COVID-19 were compared.

 CT examination of 223 patients was completed within 19 work hours. Communication, storage, and browsing of CT data via 4G and cloud technology were seamless. There were no significant differences in subjective image quality scores between groups (P > 0.05). COVID-19 pneumonia was eventually confirmed in 49 patients (21.97%). The sensitivity of initial chest CT was greater than that of the initial RT-PCR (85.71% and 67.35%, respectively) (P < 0.05).

 Screening suspected patients for COVID-19 by mobile CT in temporary hospitals and isolation points is a simple, efficient, and highly sensitive technique for early diagnosis and control of COVID-19.

Despite dual-source computed tomography (DSCT) technology has been performed well on adults or infants with heart disease, specific knowledge about children with congenital pulmonary valve stenosis (PS) remained to be established..
This original research aimed to establish a professional approach of DSCT performing technology on children and to assess the image quality performed by DSCT to establish a diagnostic evaluation for children with PS..
Patients and Ninety-eight children with congenital PS referred to affiliated hospital of Jining medical college were recruited from October 2013 to March 2015. Participants were divided into four groups according to different ages (0 - 1, 1 - 3, 3 - 7, 7 - 14), or three groups according to different heart rates ( 110). Image quality of pulmonary valves was assessed based on a four-point grading scale (1 - 4 points). Those cases achieving a score of ≥ 3 points were selected for further investigation, which played a critical role in our analysis. Correlation analysis was used to identify the effects of age and heart rate on image quality. Additionally, the results evaluated by DSCT were compared with those evaluated from the operation, further confirming the accuracy of DSCT..
Seventy-two cases (73.4%) achieved a score of ≥ 3 points based on pulmonary valve imaging, which were available for further diagnosis. There was a statistically significant difference (P Heart rate serves a pivotal role in imaging quality of DSCT. DSCT provides a functional evaluation of children with congenital PS and consequently contributes to a theoretical basis for corresponding treatment protocols..