فهرست مطالب zahra fazelinejad
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مقدمههدف از این مطالعه بررسی رابطه بین BMI و پارامترهای غلظت PSA و حجم پروستات در مردان بالای 40 سال در شهر اهواز می باشد.مواد و روش هااین مطالعه توصیفی-تحلیلی بر روی مردان بالای 40 سال به ظاهر سالم انجام شد. پارامترهایی از قبیل سن، BMI، حجم پروستات و سطح PSA در تمام افراد بررسی گردید. ارتباط بین سن، BMI، حجم پروستات و سطح PSA در مردان بالای 40 سال به عنوان پارامترهای تشخیص کانسر پروستات مورد ارزیابی قرار گرفت.نتایجدر نتیجه 180 بیمار با میانگین سن افراد مورد مطالعه 01/10 ± 61/58 سال بوده است. بین BMI و حجم پروستات (p=0.019)، BMI و سطح PSA (p=0.001)، حجم پروستات و سن بیماران (p<0.001)، سن و سطح PSA ارتباط معنی داری مشاهده گردید (r=0.821 و p<0.001). به این صورت که، افراد با BMI بالاتر دارای میانگین حجم پروستات و سطح PSA بیشتری در مقایسه با افراد با BMI پایین تر بودند، افزایش سن به طور معنی داری با افزایش حجم پروستات و سطح PSA همراه بود و به طور کل، ارتباط معنی داری بین حجم پروستات و سطح PSA مشاهده نگردید (p=0.37).نتیجه گیرینتایج این مطالعه بیمارستانی نشان می دهد که افزایش BMI و افزایش سن با غلظت PSA و حجم پروستات ارتباط مثبت دارند، اما ارتباطی بین PSA و حجم پروستات مشاهده نشد. BMI و سن ممکن است بهترین پارامتر برای تخمین غلظت PSA و حجم پروستات باشد.کلید واژگان: سرطان پروستات, سرم آنتی ژن اختصاصی پروستات, شاخص توده بدنی, سن, حجم پروستات}IntroductionThis study aims to investigate the relationship between BMI and PSA concentration parameters and prostate volume in men over 40 years old in Ahvaz City.Materials and methodsThis descriptive-analytical study was conducted on apparently healthy men over 40 years of age. parameters such as age, BMI, prostate volume, and PSA level were checked in all subjects. The relationship between age, BMI, prostate volume, and PSA level in men over 40 years of age was evaluated as prostate cancer diagnosis parameters.ResultsFinally, 180 men with the mean age of the subjects was 58.61 ± 10.01 years. A significant relationship was observed between BMI and prostate volume (p=0.019), BMI and PSA level (p=0.001), prostate volume and age of patients (p<0.001), and age and PSA level (r=0.821 and p<0.001). People with higher BMI had higher average prostate volume and PSA level compared to people with lower BMI, increasing age was significantly associated with increasing prostate volume and PSA level. There was no correlation between prostate volume and PSA level (p=0.37).ConclusionThe results of this hospital study show that increasing BMI and increasing age are positively related to PSA concentration and prostate volume, but no correlation was observed between PSA and prostate volume. BMI and age may be the best parameters to estimate PSA concentration and prostate volume.Keywords: Prostate Cancer, Prostate specific antigen, Body mass index, age, Prostate Volume}
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Association between Non-alcoholic Fatty Liver Disease and Renal Stone Formation Based on Sex and AgeGovaresh, Volume:27 Issue: 4, Winter 2023, PP 250 -258Background
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. According to previous studies, NAFLD can cause kidney dysfunction and the formation of urinary tract stones. In this study, the relationship between NAFLD and renal stone formation based on the sex and age of patients was investigated using non-contrast computed tomograms.
Material and MethodsThis study was performed in 2020 on 907 patients who were referred to Golestan Hospital and underwent computed tomography (CT) evaluation without contrast of the abdomen and pelvis. The statistical relationship between NAFLD and renal stone disease was assessed using the Chi-square test.
ResultsParticipants in this study included 582 men (64.2%) and 325 women (35.8%). The frequency of NAFLD patients with renal stones was significantly higher than NAFLD patients without renal stones (82.1% vs 17.9%, P <0.0001). The frequency of renal stones in severe NAFLD was significantly higher than in patients with mild NAFLD (100% vs 78.8%; P=0.008). The risk of developing renal stones in patients with NAFLD disease increases with age compared with patients without NAFLD (P<0.009). Renal stones in patients with NAFLD were not affected by sex (P=0.487).
ConclusionThese results show a significant association between NAFLD and renal stone formation in male and female populations. Also, this association is strengthened by the increase in the severity of NAFLD; therefore, NAFLD can be an independent risk factor for renal stone disease, and renal stone disease can be associated with metabolic syndrome or one of its components.
Keywords: Non-alcoholic fatty liver disease, renal stone disease, Non-contrast CT scan, metabolic syndrome} -
زمینه و هدف
الاستوگرافی موج برشی (Shear wave elastography) براساس سرعت انتشار shear wave به وسلیه امواج صوتی، میزان سفتی توده را تخمین می زند.
روش بررسیمطالعه حاضر از نوع آینده نگر بوده و بر روی بیمارانی که با توده پستان به مرکز درمانی بیمارستان گلستان اهواز از فروردین 1399 تا فروردین 1400 مراجعه کردند انجام شد. تنها بیماران که دارای 5-4 BI-RAD بوده اند بررسی شدند. cutoff SWE برای میانگین و ماکزیمم الاستیسیتی جهت تشخیص توده های خوش خیم از بدخیم مورد مقایسه قرار گرفتند.
یافته ها:
در این مطالعه 115 بیمار مورد ارزیابی قرار گرفتند..5/63% (73) از بیماران دارای توده خوش خیم و 5/36% (42) از نوع بدخیم بوده اند. رابطه معناداری بین سایز تومور با میانگین و ماکزیمم الاستیسیتی دیده شد. (001/0<p). نتایج نشان داد که دقت تشخیصی SWE در شناسایی توده های بدخیم نسبت به خوش خیم 100% بوده، به طوری که میانگین (kPa 03/8±61/16) و ماکزیمم (kPa 88/8±14/21) الاستیسیتی در توده های خوش خیم به طرز معناداری از میانگین (kPa 59/7±21/32) و ماکزیمم (84/8±62/91) الاستیسیتی توده های بدخیم کمتر بوده اند (001/0<p). همچنین تفاوت معناداری بین زیرگروه های 4 BI-RAD دیده شد، به طوری که در BI-RAD 4a، کمترین میانگین و ماکزیمم الاستیسیتی دیده شد. (001/0<p)
نتیجه گیری:
نتایج نشان داد که پارامترهای SWE دارای دقت تشخیصی کافی در تشخیص توده های بدخیم پستان می باشد. بنابراین، استفاده از پارامترهای کمی SWE همراه با سونوگرافی و طبقه بندی BI-RADS می توان از بیوپسی های غیرضروری جلوگیری کرد.
کلید واژگان: تراکم سینه, بیماری های پستان, تصویربرداری تشخیصی, تکنیک های تصویربرداری الاستیسیته, تصویربرداری سونوگرافی}BackgroundShear wave elastography (SWE) estimates the stiffness of a mass based on the velocity of shear wave propagation by sound waves. Due to higher cell density and angiogenesis, malignant masses have higher stiffness than benign ones.
MethodsThe present study was a prospective study and was performed on patients who were referred to Ahvaz Golestan Hospital with breast mass during March 2020 to March 2021. Only patients with 4-5 BI-RAD were evaluated. Patients were graded based on ACR BI-RAD. All patients were subjected to ultrasound and selection of BI-RAD 4-5 patients for evaluation with SWE and sampling for pathology testing. In this study, in order to increase the maximum accuracy and take samples from the main location of the lesion, sampling was done by ultrasound-guided biopsy method. Tumor information was recorded by a specialist doctor after ultrasound and SWE. This information included tumor type, tumor size and grade, presence of metastasis, involvement of lymph nodes, average and maximum elasticity. SWE cutoffs were compared for mean and maximum elasticity to distinguish benign from malignant masses.
ResultsIn this study, 115 patients were evaluated. 63.5% (73) of the patients had benign mass and 36.5% (42) had malignant ones. There was a significant relationship between tumor size and mean and maximum elasticity (P<0.001 The results showed that the diagnostic accuracy of SWE in identifying malignant masses compared to benign ones was 100%, so that the mean (16.61±8.03 kPa) and maximum (21.14±8.88 kPa) elasticity in benign masses were significantly lower than the mean (32.21±7.59 kPa) and maximum (91.62±8.84 kPa) elasticity of malignant masses (P<0.001). There was also a significant difference between the 4 BI-RAD subgroups, so that in BI-RAD 4a, the lowest mean and maximum elasticity were seen (P<0.001).
ConclusionThe results showed that SWE parameters have sufficient diagnostic accuracy in diagnosing malignant breast masses. Therefore, the use of quantitative SWE parameters in conjunction with ultrasound and BI-RADS classification can avoid unnecessary biopsies.
Keywords: breast density, breast diseases, diagnostic imaging, elasticity imaging techniques, ultrasonography imaging} -
Background
This research intended to investigate the characteristics of COVID‐19, accurately evaluate radiological findings, and compare it with laboratory evidence of coronavirus.
Materials and MethodsA retrospective study of 120 consecutive cases with a mean age of 55.9 ± 15.82 years and laboratory‑confirmed COVID‑19 pneumonia was performed. On admission, C‐reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels were tested. Computed tomography (CT) findings and scored pulmonary involvement were evaluated.
ResultsAn elevated level of CRP and mildly raised ESR was seen in all patients. ESR showed a meaningful difference between both genders (P < 0.05). Ninety‑four (78.3%) patients showed peripheral pulmonary lesions and 119 patients had ground‑glass opacity (99.2%), 110 (92.4%) had consolidation, and 9 patients (7.5%) had linear opacities. Of 120 cases, 25 (20%) had bronchial changes, 25 (20%) had air bronchogram, 11 (9.2%) had bronchial distortion, and 2 had mediastinal lymphadenopathy. The CT scores in males and females were 17.41 ± 4.86 and 14.65 ± 4.96, respectively with a significant difference between both genders (P = 0.001). CT score difference was significant between both genders (P = 0.01). The largest lung lesion diameter in both sexes (male: 46.0725.75 and female: 57.9131.14) showed a meaningful difference. CRP (r = 0.10; P < 0.05) and ESR (r = 0.15; P < 0.05) were correlated with the CT scores.
Conclusionthe results indicated that the infection involved lung parenchyma and interstitium. CRP and ESR levels were correlated with lung lesions and showed positive performance in predicting severity and disease monitoring.
Keywords: Chest computed tomography scan, COVID‐19, C‐reactive protein}
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