جستجوی مقالات مرتبط با کلیدواژه "استیل کولین استراز" در نشریات گروه "تربیت بدنی"

Caffeine affects immune response during exercise and it has shown that caffeine reduced concentration of acetyl cholinesterase and myeloperoxidase in mice trained. Thus, in this study the effect of caffeine ingestion on enzyme activities of acetyl cholinesterase and myeloperoxidase was examined after resistance exercise in athletes. 15 athletes in in a randomized, double-blind, placebo-controlled, cross-over study, received 6 mg.kg-1 of caffeine and placebo (maltodextrin) one hour before the resistance exercise (RE). After an hour blood samples were taken from the participants then they participated in resistance exercise and immediately and 15 minutes after resistance exercise, another’s blood samples were taken to analysis acetyl cholinesterase and myeloperoxidase concentration. Analysis of variance with repeated measures at α level 0.05.was used. ANOVA with repeated measures showed significant difference in concentration of acetyl cholinesterase at immediately and 15 minutes after resistance exercise between caffeine and placebo condition (p<0.05), but there was no significant difference between caffeine and placebo in relation to the concentration of myeloperoxidase (p>0.05). In terms of caffeine consumption, acetyl cholinesterase concentration was significantly lower at post compared to pre RE, but in terms of placebo consumption, acetyl cholinesterase concentration was significantly higher at post compared to pre RE (p<0.05). It seems that consumption of caffeine supplement before resistance exercise prevent increase in concentration of acetyl cholinesterase in male athletes, and possibly caffeine from this way lead to reduce inflammatory activities.

The purpose of this study was to investigate the effects of 8 weeks of resistance training (RT) on activity of total and A12 Type of acetyl cholinesterase in Soleus muscles of rats. 16 male wistar rats provided from Razi institute (age: 10 weeks and weight: 172.415±7.098 gr), were randomly divided to 2 groups (Control; n=8 and RT; n=8). Training group carried out 8 weeks (5 session/week) of resistance training on 1-meter height ladder (divided by 26 stairs) with loading 30% of their body weight (suspended from the tail) in the first week which was gradually increased to 200% in the last week. Training included 3 sets of 4 reps with 3 min rest between sets. 48 hrs after last session of training, Sol muscles of animals moved out under sterilized situation by cutting on posterio-lateral side of hind limb. For separating AchE subunits, we used from homogenization and electrophoresis (0/06 non-denaturaing Polyacrilamide). Acetyl cholinesterase activity was measured by Elisa kit. Independent t-test showed that there was no significant differences between training and control groups in both total (p=0.262) and A12 forms (p=0.246) of AchE in soleus muscle. The reason for insignificant differences in acetyl cholinesterase of soleus might be indicative of no complete involvement of this muscle in this type of training and therefore no responsiveness of acetyl cholinesterase activity of this muscle following resistance training. However, this should be studied in future with higher volume and intensity of training. Because the increases in AchE content by training is not excluded yet.

The aim of this study was to investigate the effect of 8 weeks of endurance and resistance training on the activity of G4 acetyl cholinesterase in FHL and soleus muscles of rats. 24 male Wistar rats (age: 10 weeks and weight: 171.94±8.961 gr) were randomly divided into 3 groups (control, endurance training (ET) and resistance training (RT)). ET and RT groups carried out 8 weeks (5 sessions per week) of training programs. Resistancetraining included climbing a 1-m ladder (26 stairs) carrying a weight.Results showed that the activity of this protein in fast twitch muscle of RT and ET groups increased significantly (P=0.045 and P=0.015 respectively) compared to control group, but there were no significant differences between RT and ET groups in the mean activity of this protein in the fast twitch muscle (P=0.838). Activity of this protein in slow muscle of RT group was significantly higher than control and ET group (P=0.003 and P=0.005 respectively) but there were no significant differences between control and ET groups in the mean activity of this protein (P=0.958). It seems that this resistance training protocol had a clear effect on the G4 AChE activity in both slow and fast twitch muscles, suggesting the importance of this type of training for adaptations of these muscles. Response to both types of training by fast twitch muscles could be due to more responsiveness of these muscles to training stimuli.