جستجوی مقالات مرتبط با کلیدواژه "hematopoietic stem cells cd34" در نشریات گروه "تربیت بدنی"

Cytokines and growth factors plays an important role in increasing the capacity of stem cell proliferation and migration, and recently, attention has also been paid to the role of Physical activity in this regard. The aim of this study was to determine the effect of two types of acute interval and continuous aerobic exercises on serum hematopoietic stem cell CD34 and chemokine SDF-1 in overweight women.

Thirty female overweight students volunteered to participate in the study and then were randomly divided into three equal groups (two experimental and one control group). Experimental groups performed an acute interval (2 minutes 50% and 1 minutes 80% VO2max) and a continuous (60% VO2max) aerobic exercise for 60 minutes on treadmill. The CD34 and SDF-1 indices were measured by ELISA method and the results were extracted using one-way covariance analysis, and LSD post hoc test on statistical significance as p

The acute interval and continuous aerobic exercise increased significantly the stem cells CD34 (p=0.005 & p=0.002, respectively) and the chemokine SDF-1 (p=0.0001) and there is no differences between the effect of two types of exercise on these variables (p>0.05).

The increase in these two indicators following interval and continuous aerobic exercises indicates that not only the implementation of these activities does not have a negative effect on the immune system of the participants, but also could be indication of the activation of the physiological regenerative mechanisms following exercise- induced inflammation.

The purpose of this study was to determine the effect of two different intensities of exercise on hematopoietic stem cells and relationship with some of cardiovascular risk factors in women.

Fourteen female students from a group volunteers (group 1: mean age 22 ±2 years, BMI 20.81±1.91 kg.m2, n = 7. group 2: mean age 21 ±2 years, BMI 20.38 ± 1.66 kg/m2, n = 7) were randomly selected via questionnaire and each group ran 30 minutes at their (60-75% of Vo2max) on treadmill. Blood samples were taken from all subjects for measurement of hematopoietic stem cells CD34+ and same Isotype control ratio LDL/HDL and Ch/HDL and triglyceride before and 10 minutes after the test. The related t-test (paired) were used for comparisons within a group. To compare variables between the groups were used multivariate analysis of variance test (MANOVA). For determining the relationship between variables Pearson correlation coefficient were used. Statistical significance was accepted as P<0.05.

Results of this study showed that both intensities of exercise increased significantly the number of CD34+ cells, this effect was higher in intensity of 75% VO2max, but was not statistically significant. No significant correlation between CD34+ and ratio LDL/HDL and Ch/HDL and triglyceride was observed.

according to the findings the present study can be expressed that physical activity with intensity 60% and 75% VO2max can increase re-enthotelialisation due to mobilization of CD34+ cells.