جستجوی مقالات مرتبط با کلیدواژه « اینترلوکین-10 » در نشریات گروه « تربیت بدنی »

The inflammatory factors can be considered as one of the important factors involved in metabolic disorders and diabetes. The identifying of the best type of exercise training has been considered as an important method for reducing inflammation. The purpose of this study was to compare the effects of six weeks aerobic, resistance and concurrent exercise trainings on plasma levels of IL-10/TNF-α ratio and insulin resistance index in diabetic male Wistar rats.

The research was performed as an experimental research method. Statistical population were consisted of male Wistar rats with a weight range of 130 to 150 gr. Forty male Wistar rats were randomly divided into five groups (n=8) including resistance training (intensity about 60% one repetition maximum), aerobic training (intensity of 50-60% VO2max), concurrent training, diabetic control and inactive healthy control groups. All groups performed their relevant exercises for six weeks/three times in each week. Forty eight hours after of last training session, blood samples were taken directly from the heart and blood data were collected. Inflammatory factors and insulin resistance were measured by ELISA and HOMA-IR methods respectively. The one-way analysis of variance and LSD post hoc statistical methods were applied at a significant level of p≤0.05.

Levels of IL-10/TNF-α ratio in diabetic control (p=0.001), aerobic training (p=0.02), resistance training (p=0.003) and concurrent training (p=0.003) groups significantly decreased compared to healthy control. On the other hand, in training groups compared to diabetic control, no significant change was observed (p>0.05). Moreover, insulin resistance index in aerobic, resistance and concurrent training groups (p=0.002, p=0.03 and p=0.01 respectively) significantly decreased compared to the diabetic control. No significant differences were observed between the training groups.

Performing of resistance, aerobic and concurrent exercises for six weeks improves type II diabetes; but it probably does not have enough potential to improve the body’s inflammatory conditions.

Obesity is one of the most important public health challenges of the present century, which increases the plasma levels of inflammatory cytokines and decreases anti-inflammatory and anti-atherogenic agents. High intensity interval training may be able to stop or reverse these destructive effects. Therefore, the aim of this study was to investigate the effect of 8 weeks of interval training on inflammatory factors in overweight adolescent boys. In a quasi-experimental research project, from overweight adolescent boys (13-18 years old, mean height 154.33 cm, mean body mass index 27.05 kg/m2), 30 subjects were voluntarily assigned to 3 groups (10 subjects each group): short-term interval training (nine 30-second bouts, 100 to 110% of maximum speed with 150 seconds of rest), long-term (four 150-second bouts, 90 to 95% of maximum speed with 240 seconds of rest) and control. 48 hours before the beginning and the end of the training protocol, weight, height, body mass index and fat percentage were measured by a body composition apparatus and blood samples were collected to determine the interleukin-6, interleukin-10 and C-reactive protein indices. The results showed that 8 weeks of high intensity interval training increased interleukin-10 and decreased C-reactive protein. But it had no significant effect on interleukin-6. It was also found that there were no differences between short-term and long-term HIIT in influencing the desired indicators. Based on these findings, it can be said that overweight or obese adolescents may be able to use HIIT to boost their anti-inflammatory system by increasing interleukin-6 and decreasing C-reactive protein. But more studies are needed to determine the effect of this training on interleukin-6.

The aim of this study was to investigate the effect of carbohydrate solution supplementation and pure water on interleukin 10, glucose and blood hematological indexes in male football players. 30 male football players from the Mes Club of Kerman (mean age of 17 ± 2.0) were selected and were randomly divided into 3 groups: carbohydrate intake (n=11), pure water (n=11) and control (n=8) after primary evaluations. Subjects then performed a 90-minute football match. The carbohydrate and pure water groups consumed 150 cc of their solutions (300 cc in total) in each half. Blood samples were collected before, immediately after and 24 hours after the match. Simax device and Eliza Reader were used to measure blood hematological indexes (WBC, RBC, PLT, MCV, HGM, HCT) and IL-10 respectively. For statistical analysis of data, analysis of covariance with repeated measures was used at the significance level of P

The purpose of this study was to investigate the effects of high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on inflammatory factors (TNF-α and IL-10) in obese male rats. Forty male rats were divided into two groups: high-fat diet (n=32) and standard diet (n=8), for 10 weeks. After inducing obesity, eight rats from the high-fat diet group (O) and eight from the standard dietary group (C) were sacrificed, and the other obese rats were randomly divided into three groups: obesity control (OC), moderate intensity continuous training (MICT) and high intensity interval training (HIIT). The HIIT protocol, including 10 bouts of 4-minute activity with equivalent intensity of 85-90% vo2max and 2 minute active rest periods, and the MICT protocol with equivalent intensity of 65-70% VO2max, with covered distance matched to that of the HIIT protocol, were performed for 12 weeks and 5 sessions per week. Serum samples were collected to measure serum levels of TNF-α and IL-10 by ELISA. In both HIIT and MICT groups, serum levels of TNF-α were significantly decreased and serum levels of IL-10 were significantly increased compared to OC group (P<0.05). But there was no significant difference between the HIIT and MICT groups in serum levels of TNF-α and IL-10. It seems that both HIIT and MICT training protocols improve chronic inflammation by decreasing TNF-α and increasing IL-10.

Increased anti-inflammatory cytokines and decreased inflammatory cytokines through exercise is one of the ways to reduce chronic inflammation. Current study aimed at investigating the effect of endurance training on inflammatory markers in male smokers. Two groups: experimental (mean age 25.30 ± 2.95 years, n=10) and control (mean age 26.11 ± 2.76 years, n=10) were selected randomly. Endurance training protocol including of 20 minutes of running with intensity of 55-65% of heart rate reserve was performed by the experimental group during six weeks. 48 hours after the last training session, measurements similar to those before training and blood samples were collected. The data were analyzed by dependent t test within a group and independent t test between the groups (α≤0.05). The results showed that six weeks of endurance training intervention significantly decreased CRP (P=0.012) and significantly increased IL-10 (P=0.01) in the experimental group. The results indicated the effect of exercise on inflammatory markers in male smokers. On the other hand, these findings show that smokers may reduce the side effects of smoking if they have endurance training. But this requires further research on the role of endurance training and its relationship to inflammation.

According recent evidence, regular exercise training can reduce the chronic inflammation. The
aim of this study was to investigate the effect of 8 weeks of endurance exercise training on serum levels of IL-10 and body composition of sedentary overweight women. Twenty tow middle aged overweight (BMI>25 kg/m2) and sedentary women were from Pardis city randomized divided into two groups including control (C) and exercise training (EX) groups. Endurance exercise training group participated in running exercise on a treadmill (three sessions per week) for 8 weeks, 20-30 min per session, at 50-70% their maximal reserve heart rate. Blood samples were collected in fasting state at 48 hours before starting training and 48 hours after last exercise session. IL-10 level were measured ELISA assay. Results were extracted by analysis of covariance (ANCOVA) method at significant level of p<0.05. Body fat percent (p=0.002), BMI (p=0.01 ) and WHR (p=0.04) of exercise group significantly decreased in compare to control group but there was no significant changes in IL-10 (p=0.52) levels and fat-free mass (p=0.11). Endurance exercise training can play important role in prevention of diseases-induced overweight by improvement of body composition; however it seems that more studies will be needed for obtaining the anti-inflammatory effects of such exercise

To perfume continuous vigorous physical activities above the lactate threshold (vco2 / vo2>1) at the Olympic competitions level or for the elite athletes probably lead to the overtraining syndrome is due to an imbalance condition between the overloading period for complex cardio metabolic system which can exercise and recovery situations of sports events to deteriorate the safety and an efficiency of the organism and the athletic performance. In this study the effect of 700IU vitamin E supplementation during an overtraining program on the plasma concentrations of interleukin 10(IL-10) was evaluated in the free style wrestlers.
This design was performed on the 27 free style wrestlers. Overtraining syndrome measurement was Fulfulde using a standard questionnaire overtraining. The subjects participated in the three groups: including an overtraining vitamin E (G1), a training placebo (G2) and an without overtraining vitamin E (G3). Plasma levels of IL-10 were measured before (base line condition) and after an intervention agent.
The findings indicated that a significant decreasing in plasma concentration of IL-10 wrestlers during an overtraining VE group and the group without overtraining VE, were observed after an intervention condition (p The scientific evident investigated that biological role of vitamin E supplementation for the immune system and its probably impact on the suppress adipocytokine (IL-10 ), oral administration of 700IU of the Vitamin E is markedly occurred in the reducing for the plasmatic level of IL-10 wrestlers during an overtraining conditions in the completion precession.