جستجوی مقالات مرتبط با کلیدواژه « تمرین ترکیبی » در نشریات گروه « زیست شناسی »

Diabetes is one of the main causes of death in developing countries, which can be improved by various factors such as physical activity and proper diet. The purpose of this study was to investigate the effect of broccoli powder consumption along with combined training on some selected hepatokines in men with type 2 diabetes. This research was semi-experimental and practical type and was pre-test and post-test. For this purpose, 44 diabetic male volunteers were randomly divided into 4 groups of 11 people including control (placebo recipient), supplement (supplement recipient), exercise + placebo groups, and exercise + supplement. The training protocol included 45 minutes of resistance training with an intensity of 60-70% of one maximum repetition, 30 minutes of aerobic exercises (running) with an intensity of 60-70% of the maximum heart rate. Broccoli (supplement) was also prepared in powder form and 10 grams per day was given to each volunteer for 12 weeks. Blood samples were taken 48 hours before the first training session and 48 hours after the last training session and were used to analyze the indicators. Intergroup analysis of data was done using a two-way analysis of variance and a correlated t-test was used for intra-group differences. A significant difference between the groups was observed in ANGPTL3 and ANGPTL4 (P<0.001). Also, the examination of changes within the group showed that in supplementary, exercise, and supplementary exercise groups, a significant decrease was observed in ANGPTL3 and ANGPTL4 (p < 0.05). The results of the present study showed that 12 weeks of combined exercise along with broccoli supplementation improves selected hepatokines and insulin resistance. This improvement was greater in the group that exercised and took supplements at the same time.

Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the level of adiponectin gene expression in the hand and leg muscles of Wistar rats.

The current study is an experimental research in which 40 healthy male Wistar rats were divided into four ten groups of control, resistance training, endurance and combined. Each group did their own exercises for 8 weeks. Finally, hand and foot muscles were examined to measure the adiponectin gene.

The results of the analyzes showed that the level of adiponectin gene expression was different among all groups (P < 0.001). The relative expression of adiponectin gene in all training groups increased significantly compared to the control group (P < 0.001).Also, comparing exercise groups together, combined exercises had the greatest effect and resistance exercise had the least effect. In intra-group comparison, adiponectin gene expression was higher in hand muscle than leg muscle during resistance training (P = 0.047), but gene expression was higher in leg muscle during endurance training (P = 0.029). These two muscles were not significantly different during combined training (P = 0.086).

According to the results of this study, all types of sports training can increase the expression of adiponectin gene, but combined, endurance and resistance training have the greatest effect, respectively.

Due to the complications caused by surgery, especially involuntary immobility, patients' ability to function is significantly reduced after surgery, so participation in exercise and rehabilitation programs is recommended to patients. The aim of this study was to investigate the effect of interval training and two types of combination on angiopoietin 1, 2 levels in patients in the postoperative rehabilitation period (CABG). A total of 30 cardiac patients operated on in Tehran Heart Center were selected by simple random sampling and randomly divided into three groups (10 patients in each group): interval training, interval training-resistance and continuous-resistance. Exercises were performed for 6 weeks and 3 sessions per week. Interval training were performed from the first to the sixth week with an intensity of 60 to 80% of the maximum heart rate. Continuous exercises were performed from 10 to 20 minutes of activity with an intensity of 60 to 70% of the maximum heart rate. Resistance training included four movements of the upper chest, biceps flexion, thigh extension, and inside the thigh. 2 sets of 10-12 repetitions with an intensity of 50-70% of the maximum repetition were performed from the first to the sixth week. Blood samples were taken 48 and 24 hours before and after the training protocols and the expression of angiopoietin 1, 2 genes was measured by real-time-PCR. The results within the group indicate that there is a significant difference between the pre-test and post-test of angiopoietin 1, 2 in all groups (p ≤ 0.05). Also, comparison of intergroup results in angiopoietin variable 1 and 2 showed that there was no significant difference between training groups in the post-test stage (p ≥ 0.05). All three training methods were able to improve the expression of the studied genes, to make favorable changes in reducing the consequences of heart tissue damage.

Diabetes is one of the leading causes of mortality in developing countries that can be improved by various factors such as physical activity and proper diet. The present study was aimed at examining the effect of broccoli powder supplementation with combined exercise training on FGF-21 and insulin resistance in type 2 diabetes men. This experimental design was conducted with pre-test and post-test and four groups. To this end, 44 volunteer diabetic men after homogenization based on individual characteristics were randomly assigned to four groups of 11 individuals including exercise-supplement group, exercise-placebo group (exercise), control-supplement group (supplement), and control-placebo (controls). Combined exercise program included 12 weeks, three sessions per week. Moreover, broccoli supplement was 10 grams per day for 12 weeks. The blood sample was taken 48 hours before and 48 hours after the last training session and used for analysis. Analysis of intergroup indicators revealed a significant difference between the groups in FGF-21 (p = 0.017) and insulin resistance (p = 0.01). Significant changes in the measured indices were also observed in the intragroup changes (p < 0.05). The results of this study showed that 12 weeks of combined exercise with broccoli supplement significantly reduced FGF-21, blood glucose, and insulin resistance in all three groups of exercise- supplement, exercise, and supplement. Therefore, incorporating broccoli into the diet can partially prevent the risky effects of type 2 diabetes.

Cardiovascular diseases are the leading causes of mortality and death in all areas of the world except Africa. This study aimed at the effect of eight-week combined training on Endostatin and VEGF gene expression in CABG patients.This is an applied and semi-experimental research with two groups (interventional and control), which was conducted as a pretest and posttest. 30 middle-aged CABG men were selected using purposive sampling based on inclusion criteria. Participants were randomly divided into two groups of control and combined training. Quantitative Real-time PCR was utilized  to measure Endostatin and VEGF gene expression levels. The eight-week combined exercise training was conducted in three sessions per a week. Dependent t-test and independent t-test were used to data analysis. A significant increase was observed after eight weeks of combined training on VEGF gene expression in CABG  patients. (p=0.001), but it was not Significant on Endostatin gene expression( p=0.38) . Eight weeks of combined  Cardiac Rehabilitation training as the protocol used in  this research increased the expression of the VEGF gene in CABG patients , but there were not any significant changes on Endostatin gene expression by this way. As a result, the increase in the VEGF gene is one of the results of adaptation to the combined exercise activity used in this study, and it appears that physical activity is an important and effective factor in the process of angiogenesis, and can play a key role in the prevention of cardiovascular diseases.

Rehabilitation training in cardiac patients after coronary artery bypass graft (CABG) improves several physiological capacities. The aim of this study was to investigate the effect of eight weeks of combined training on plasma levels and ghrelin gene expression in PBMNC among CABG patients. In this quasi-experimental study, 30 cardiac patients of Javad Al-Aemeh cardiac specialty hospital of Mashhad, who underwent CABG operation, were selected using convenience and purposeful sampling method and randomly divided into two equal groups (n=15): combined training and control. The combined training group performed selected aerobic and resistance training protocols for eight weeks, three sessions per week. Before and after training program, body composition assessments and blood sampling were performed to measure variables. Then, the obtained data were analyzed using independent and dependent t-tests at the significance level of 0.05. Data analysis showed that combined training significantly reduces body weight and BMI and significantly increases plasma ghrelin levels and relative expression of ghrelin gene in PBMNC (P≤0.05). Additionally, a significant difference was observed between plasma ghrelin levels and relative expression of ghrelin gene in PBMNC of training group compared to control group (P≤0.05). It seems that eight weeks of combined rehabilitation training increases plasma levels and ghrelin gene expression in PBMNC among CABG patients and can promote desirable physiological adaptations in cardiovascular health.

Inroduction & Objective Colorectal cancer is third cancer incident in all of the world and Iran which is enhancing, unfortunately. Physical activity is one of the best effective interventions. The aim of this research was to investigate of concurrent training programme on aerobic capacity and lower body power of colorectal cancer survivors.
20 colorectal cancer patients with average age 55.5±20 and average weight 70.9±9.35 participated at this survey. They randomly divided in two groups. Experimental group(EG) performed 14 week’s concurrent training programme which involved 3 days endurance training and 2days resistance training per week. Control group(CG) didn’t any training programme at this time. Lower body strength measured by 1RM and Aerobic capacity measured by VO2Max. To analyse the data T-test and Covariance were used.
On the base of results, significantly differences observed between EG and CG in VO2Max and lower body power variables (P
Conclusion The concurrent training programme probably is effective intervention for prevention of return of cancer which is able to improve physical capacities in colorectal cancer survivors.