جستجوی مقالات مرتبط با کلیدواژه « anti oxidant » در نشریات گروه « زیست شناسی »

The aim of this study is to synthesize and investigate the anti-oxidant, anti-inflammatory and anti-bacterial effects of polylactic acid (PLGA) nanoparticles containing the extract of Anbernesara smoke. For this purpose, Anbernesara smoke was extracted and encapsulated by PLGA nanoparticles using the W1/O/W2 method and characterized by DLS, zeta potential, FESEM and FTIR electron microscope techniques. The antioxidant activity of the synthesized nanoparticles using ABTS and FRAP tests, as well as measuring the expression levels of the antioxidant genes catalase (CAT) and superoxide dismutase (SOD) and the expression of interleukin 6 (IL-6) and interleukin 10 (IL- 10) was also analyzed to determine the anti-inflammatory potential of nanoparticles by Real time PCR test. The antibacterial activity of the synthesized nanoparticles was evaluated on two bacterial strains Escherichia coli and Bacillus subtilis. The results showed the formation of spherical nanoparticles with an average size of 51.2 nm, dispersion index of 0.22, surface’s charge of -35.37 mV and encapsulation efficiency of 74%. The antioxidant properties of synthesized PLGA nanoparticles were confirmed by reducing Fe+3, inhibiting the formation of free radicals and increasing the expression level of CAT and SOD genes. The expression levels of IL-6 and IL-10 genes were also increased under the influence of PLGA nanoparticles loaded with the organic extract of Anbernesara smoke, indicating the anti-inflammatory properties of the proposed nanoparticles. PLGA nanoparticles loaded with the organic extract of Anbernesara smoke had an antibacterial effect on B. subtilis, but not on E. coli. The PLGA nanoparticles loaded with the organic extract of Anbernesara smoke have anti-oxidant, anti-inflammatory properties and can be considered as a combination with antibacterial potential.
.

in this study was tried Different tomato varieties based on phytochemical and morphological traits as well as antioxidant properties of leaf In the form of two germination experiments in laboratory and pot plants in a greenhouse, completely randomized in three replications. Totally two experiments, different varieties of tomatoes were different (P<0.01) in terms of chlorophyll a, chlorophyll b, carotenoid, catalase, guaiacol, ascorbic peroxidase, polyphenol oxidase and phenylalanine, fresh weight and number of stems, germination percentage, dry weight, stem length, root length, except for the number of stems And plant height. In first experiment; The highest levels of chlorophyll a (189.99 mg/g fresh weight), chlorophyll b (6.145 mg/g fresh weight), and carotenoid (6.5015 mg/g fresh weight) was belong to Iran's Queen2274 cultivar. In second experiment; the highest amount of catalase (0.0196, 0.0192 and then 0.0181 mg/g fresh weight of extract) respectively was related to PS and Falat 111 from USA and then Queen2274 from Iran. The highest amount of Guiacol (0.0244 and 0.127 mg/g fresh weight of the extract) respectively was related to the French Clouse cultivar and the Italian Falat Y variety, respectively. Ascorbic peroxidase (0.0140 and 0.0136 mg/g fresh weight of extract), respectively, was related to Newton cultivar Holland and then French Clouse cultivar. Polyphenol oxidase (0.0112 and then 0.628 mg/g fresh weight of extract) was related to Iranian Queen2274 cultivar and USA PS cultivar. Maximum amount of phenylalanine (0.25 mg/g fresh weight of extract) was related to Iran's Queen2274 cultivars and USA PS cultivar. Based on the results of this research is suggested to obtain the best cultivar which has high levels of enzymatic and non-enzymatic antioxidants, the Queen2274, Clouse and PS varieties can be used as breeding program and produce superior cultivars.

Aim and Curcumin is the yellow pigment derived from rhizome of turmeric. Curcuminoids are natural phenols that used in natural medicine for thousands of years. Currently antioxidant and anti-inflammatory properties of this material are considered in clinical practice. However, a little study that has been done on the effect of curcumin on a reproductive system.
This study was an experimental study, 40 male NMRI mice weighing 20 to 30 grams were investigated. The rats were randomly assigned to four groups: control, treated with 10mg / kg / Day DEHP, DEHP treatment group with curcumin and curcumin group. After two weeks body weight of mice were measured. Right and left testis was weighed separately. The genital pore distance (AGD) was measured. The blood was drived from the heart, testosterone, and dehydroepiandrosterone performed by ELISA Mehod on mice serum. Testicular samples were cutting 5 microns and stained with hematoxilina-eosina method, ultimately were evaluated.
The study demonstrated protective effects of Curcumin on testis of mice. So that daily administration DEHP10mg / kg / day with 5 ml curcumin can improve the parameters of body weight (p = 0.000), testicular right and left (p = 0.000) and serum testosterone (p = 0.026) compared to mice treated with DEHP was alone. Also microscopic pathological waste, including demolition of Sertoli cells and Leydig cell necrosis in the group treated with DEHP was found in the group treated with curcumin DEHP were improved.
Curcumin protects testicular tissue from free radicals induced of phthalates by antioxidant properties. It also modulates the testoster hormone as a regulator of reproduction, weight and growth process.

The aim of this study is an investigation of most important ecological requirements, essential oil composition, total phenol, flavonoid and antioxidant activity of Phlomis herba-venti in HezarJerib area of Behshahr, Mazandaran province. Along with the review of floristic list of species in the study area, the most important of ecological requirements, their Ethno pharmacology and phenology were recorded and studied. The aerial parts of plant in blooming were collected in June 2015 from Hezarjerib area ( 1000- 2000 m) . Five soil samples were taken to evaluate the physical and chemical properties of soil. Essential oil was obtained by water distillation method (Clevenger apparatus) and were analyzed by GC and GC/MS. The ethanol extracts were obtained by percolation method. Total phenol (TP) and total flavonoids (TF) were measured by spectrophotometery and antioxidant activity was measured by scavenging free radicals of DPPH. Results were showed that the Phlomis herba-venti usually was grew wild in 2000 m region with average annual rainfall 383 mm, the average annual temperature 12.44 Co, organic matter percentage 5.06%, pH 7.53, EC 0.62 in and sandy loam soil . The plant vegetative growth in early May, flowers appeared in June and fruit disperse in late of September. Biological spectrum was showed that 47 genus and 55 species were grew wild in this region and the Phlomis herba-venti has been used as anti inflammation and anti infection in traditional medicine of this region. Germacrene-D (54.47%) and caryophyllene (15.81%) were the main essential oil component of this plant. Total phenol content (120.40 mg GAE g 01 DW) and total flavonoids content (3.2 mg QUE g 01 DW) were reported and the antioxidant activity were determined with IC50=3.9 ppm. So these results were confirmed the traditional uses of this plant in this area as an anti inflammation and anti infection.

Aims & Due to Micro algae properties including nutritional value, medicinal properties, high amount of protein, vitamins, minerals, natural pigments such as phycocyanin and Carotenoids, they can use in the food industry - hygienic, cosmetics, food additives for human, animals, poultry and Aqua feed. Carotenoids are an important group of natural pigments, which produce only by plants and micro algae; in addition they have also antioxidant properties which make them useful for medical applications. This study was conducted to identify the micro algal species by standard techniques such as morphological and biochemical characteristics
In this study, the samples were isolated and purified from Golestan coasts, Khazar Lake and cultivated in F/2 & BBM medium. The following method was used for measurements: Methanol extraction Lichtenthaler for total carotenoids and chlorophyll and DPPH for antioxidant activity.
The purpose of this study was to investigate the potential locally Micro algae from Golestan coasts as a Carotenoids Source. Morphological characters identification has confirmed, Selenastrum sp. Chlorella volgaris , Chlamydomona debaryana ,Chlorella sorkinia as isolated species. Their Chlorophyll a concentration were 6.7, 5.1, 12.5, 7.8 and concentration total Carotenoid 2.2, 1.4, 2.4, 1.6 mg/gr total respectively. IC50 of isolates methanol extract were 2.87, 4.03, 2.78, 3.75 mg and IC50 of isolates hexan extract were 6.49, 4.9, 3.75, 8.35mg.
There is a high diversity of microalgae in Iran with unknown applied potential. Thus in this study we have isolated four strains and their characters have investigated. Based on the results antioxidant activity of methanol extract is upper than anti oxidant activity of hexan extract. The highest anti oxidant activity was seen in Chlamydomona debaryana.