جستجوی مقالات مرتبط با کلیدواژه « lipid profiles » در نشریات گروه « زیست شناسی »

Fatty liver contains a range of clinical symptoms, including the accumulation of fat in the liver cells and it varies from a simple steatosis to nonalcoholic steatohepatitis and cirrhosis. Using natural therapies has always been a great concern for such health-related diseases. Herein, nerol, as a natural monoterpene, was applied to treat nonalcoholic fatty liver-induced NMRI (Naval Medical Research Institute) mice. The assessment included histological studies of the liver along with measurement of biochemical parameters, including insulin, glucose, HDL-C (high-density lipoprotein cholesterol), LDL-C (low-density lipoprotein cholesterol), Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), SOD (superoxide dismutase), and catalase. The results demonstrated that treatment with nerol (90 mg/kg) modified the fatty liver indices by significantly reducing the levels of triglyceride, cholesterol, LDL-C, glucose, and insulin (p <0.001) whereas this treatment notably increased the levels of liver antioxidant enzymes, and HDL-C (p <0.001). Nerol administration also improved the status of the liver tissue of the fatty liver condition. Therefore, nerol, in a dose-dependent mode, showed capability of improving nonalcoholic fatty liver and could offer a reliable remedy.

This study was concentrated on the algae effects and compare it with the atorvastatin drug on the lowering of cholesterol and blood sugar.

In this research 24 native breed dogs were used for 30 days, the dogs were divided into three groups of eight, a group of control, a group orally receiving 2 gr Spirulina, and receiving a group of 5 mg/kg of Atorvastatin, and then blood samples were analyzed.

We observed mainly reduction and increase in blood glucose in Spirulina and atorvastatin receiver groups respectively (P= 0.001). Evaluation of lipid factors in dogs were declined in total cholesterol, Low-Density Lipoprotein levels, and Triglyceride factors (P<0.001). This research illustrated that the use of Spirulina in dogs for a short time could improve lipid and liver factors.

Considering that the results of the present study are showed that using Spirulina can be concluded without worrying about allergic reactions and its side effects. It can also be used as a replacement for chemical drugs.